Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 137349..138007 Replicon plasmid pRSMBA
Accession NZ_CP020385
Organism Rhodovulum sp. MB263

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag B5V46_RS18765 Protein ID WP_080618212.1
Coordinates 137606..138007 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag B5V46_RS18760 Protein ID WP_080618211.1
Coordinates 137349..137606 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5V46_RS18745 133014..135419 + 2406 WP_080618208.1 response regulator -
B5V46_RS18750 135416..136099 + 684 WP_080618209.1 response regulator transcription factor -
B5V46_RS18755 136219..137241 + 1023 WP_080618210.1 LLM class flavin-dependent oxidoreductase -
B5V46_RS18760 137349..137606 + 258 WP_080618211.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
B5V46_RS18765 137606..138007 + 402 WP_080618212.1 type II toxin-antitoxin system VapC family toxin Toxin
B5V46_RS18770 138030..139223 - 1194 WP_080618213.1 replication initiation protein -
B5V46_RS18775 139818..141221 + 1404 WP_080618214.1 AAA family ATPase -
B5V46_RS18780 141223..142317 + 1095 WP_080618215.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..238713 238713


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-117)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-50)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14780.97 Da        Isoelectric Point: 5.6618

>T74558 WP_080618212.1 NZ_CP020385:137606-138007 [Rhodovulum sp. MB263]
MYLIDTNVISAVRRPERAPQVRAWLAARPEPELYLSVITLGEIERGIRQQETRDPGFARDLRVWLDRTMLVFADRLLPFG
AAEARIWGRLSAEIGHPGADLMIAATALHHGATVVTGNVPDFEPTGVPIENPF

Download         Length: 402 bp

>T74558 NZ_CP020385:137606-138007 [Rhodovulum sp. MB263]
ATGTATCTGATCGACACCAACGTGATTTCCGCGGTGCGCCGTCCCGAGCGCGCGCCGCAGGTCCGCGCCTGGCTGGCCGC
GCGGCCCGAGCCCGAGCTTTATCTCAGCGTCATCACCCTGGGCGAGATCGAACGCGGCATCCGCCAGCAAGAGACCCGCG
ATCCCGGTTTCGCCCGCGACCTGCGGGTCTGGCTCGACCGTACCATGCTGGTCTTCGCCGACCGGCTCTTGCCCTTCGGC
GCGGCCGAGGCGCGGATCTGGGGCCGGCTTTCGGCCGAGATCGGCCATCCCGGCGCCGACCTGATGATCGCGGCGACTGC
GCTTCACCACGGCGCGACGGTGGTCACCGGCAATGTCCCGGATTTCGAACCGACCGGCGTTCCGATCGAGAACCCGTTCT
GA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9415.80 Da        Isoelectric Point: 10.0754

>AT74558 WP_080618211.1 NZ_CP020385:137349-137606 [Rhodovulum sp. MB263]
MWTLQDAKNRFSAVVEAALAGVPQEVTRRGKPAVVVLSADDYRRLLKGAAAARESFAEHLLAFPAPGIEAREIERAEVRP
RDVRF

Download         Length: 258 bp

>AT74558 NZ_CP020385:137349-137606 [Rhodovulum sp. MB263]
ATGTGGACATTGCAGGATGCCAAGAACCGGTTCAGCGCGGTGGTCGAGGCAGCGCTGGCCGGGGTCCCCCAGGAGGTCAC
CCGCCGCGGCAAGCCCGCGGTCGTGGTGCTGTCGGCCGATGATTACCGGCGCCTGCTGAAAGGCGCCGCCGCCGCCCGCG
AAAGCTTTGCCGAGCATCTGCTGGCCTTCCCTGCCCCCGGGATCGAGGCCCGCGAGATCGAGCGCGCCGAGGTCCGCCCG
CGCGACGTCCGCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References