Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 1654161..1654755 Replicon chromosome
Accession NZ_CP020384
Organism Rhodovulum sp. MB263

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag B5V46_RS07835 Protein ID WP_080616079.1
Coordinates 1654161..1654346 (+) Length 62 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag B5V46_RS07840 Protein ID WP_080616080.1
Coordinates 1654363..1654755 (+) Length 131 a.a.

Genomic Context

B5V46_RS07790B5V46_RS19710B5V46_RS07800B5V46_RS07835B5V46_RS07840B5V46_RS07850B5V46_RS07855B5V46_RS07860B5V46_RS20210B5V46_RS07805B5V46_RS07810B5V46_RS07815B5V46_RS07820B5V46_RS07825B5V46_RS07830B5V46_RS07845B5V46_RS20205B5V46_RS20215
Location: 1649524..1650408 (885 bp)
Type: Others
Protein ID: WP_080617988.1
Location: 1650739..1650958 (220 bp)
Type: Others
Protein ID: Protein_1568
Location: 1651045..1651260 (216 bp)
Type: Others
Protein ID: Protein_1569
Location: 1654161..1654346 (186 bp)
Type: Toxin
Protein ID: WP_080616079.1
Location: 1654363..1654755 (393 bp)
Type: Antitoxin
Protein ID: WP_080616080.1
Location: 1655624..1655818 (195 bp)
Type: Others
Protein ID: WP_080616082.1
Location: 1655959..1656210 (252 bp)
Type: Others
Protein ID: WP_080616083.1
Location: 1656211..1657521 (1311 bp)
Type: Others
Protein ID: WP_080616084.1
Location: 1657925..1658176 (252 bp)
Type: Others
Protein ID: Protein_1583
Location: 1651594..1651923 (330 bp)
Type: Others
Protein ID: WP_080616073.1
Location: 1651932..1652429 (498 bp)
Type: Others
Protein ID: WP_080616074.1
Location: 1652434..1652646 (213 bp)
Type: Others
Protein ID: WP_080616075.1
Location: 1652746..1653057 (312 bp)
Type: Others
Protein ID: WP_080616076.1
Location: 1653062..1653520 (459 bp)
Type: Others
Protein ID: WP_080616077.1
Location: 1653520..1653972 (453 bp)
Type: Others
Protein ID: WP_080616078.1
Location: 1654764..1655360 (597 bp)
Type: Others
Protein ID: WP_080616081.1
Location: 1657683..1657925 (243 bp)
Type: Others
Protein ID: Protein_1582
Location: 1658180..1658458 (279 bp)
Type: Others
Protein ID: WP_080616085.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B5V46_RS077901649524..1650408+885WP_080617988.1follicular epithelium yolk protein subunit-
B5V46_RS197101650739..1650958+220Protein_1568transposase-
B5V46_RS078001651045..1651260+216Protein_1569IS110 family transposase-
B5V46_RS078051651594..1651923-330WP_080616073.1bacteriophage spanin2 family protein-
B5V46_RS078101651932..1652429-498WP_080616074.1lysozyme-
B5V46_RS078151652434..1652646-213WP_080616075.1hypothetical protein-
B5V46_RS078201652746..1653057-312WP_080616076.1hypothetical protein-
B5V46_RS078251653062..1653520-459WP_080616077.1hypothetical protein-
B5V46_RS078301653520..1653972-453WP_080616078.1hypothetical protein-
B5V46_RS078351654161..1654346+186WP_080616079.1type II toxin-antitoxin system HicA family toxinToxin
B5V46_RS078401654363..1654755+393WP_080616080.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
B5V46_RS078451654764..1655360-597WP_080616081.1hypothetical protein-
B5V46_RS078501655624..1655818+195WP_080616082.1hypothetical protein-
B5V46_RS078551655959..1656210+252WP_080616083.1helix-turn-helix transcriptional regulator-
B5V46_RS078601656211..1657521+1311WP_080616084.1type II toxin-antitoxin system HipA family toxin-
B5V46_RS202051657683..1657925-243Protein_1582hypothetical protein-
B5V46_RS202101657925..1658176+252Protein_1583zinc ribbon domain-containing protein-
B5V46_RS202151658180..1658458-279WP_080616085.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1639656..166595626300


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(7-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(4-124)


Sequences

Toxin        


Download         Length: 62 a.a.        Molecular weight: 7041.28 Da        Isoelectric Point: 11.0108

>T74555 WP_080616079.1 NZ_CP020384:1654161-1654346 [Rhodovulum sp. MB263]
MLETNSRKIVKRLEQDGFELVKVTGSHPKFRKGDRIVTIPHPKKDLPIGTVRNIYKQAGWL

Download         Length: 186 bp

>T74555 NZ_CP020384:1654161-1654346 [Rhodovulum sp. MB263]
ATGCTCGAGACCAACAGCCGCAAGATCGTCAAGCGTCTCGAGCAAGACGGCTTCGAGCTGGTGAAGGTCACCGGGTCGCA
CCCCAAGTTTCGCAAGGGCGACAGGATCGTGACGATCCCCCACCCGAAGAAGGACCTGCCCATCGGCACGGTCCGCAACA
TCTACAAACAGGCCGGCTGGCTGTAA

Antitoxin


Download         Length: 131 a.a.        Molecular weight: 13891.67 Da        Isoelectric Point: 4.4859

>AT74555 WP_080616080.1 NZ_CP020384:1654363-1654755 [Rhodovulum sp. MB263]
MRHYIGVVHQEDDSAFGIHFPDVPGCFSAADALDDLLSNASEALALHLEDEVLPEARSLDAVRADSDVARDLEAGAFLLA
VPFFRLSGRTAKANITMDAGLLAAIDQTAKARGLTRSAFLADLARREIIG

Download         Length: 393 bp

>AT74555 NZ_CP020384:1654363-1654755 [Rhodovulum sp. MB263]
ATGCGTCACTACATCGGCGTCGTGCACCAGGAAGACGACAGCGCCTTCGGCATCCATTTCCCCGACGTGCCCGGCTGCTT
CTCGGCCGCCGATGCGCTCGACGATCTTCTGTCCAATGCCAGCGAGGCGCTCGCGCTTCATCTCGAGGACGAGGTCCTGC
CCGAGGCGCGCAGCCTCGATGCCGTTCGCGCCGACAGCGACGTGGCCCGCGACCTCGAGGCGGGGGCCTTCCTTCTGGCG
GTGCCGTTCTTCCGCCTGAGCGGGCGGACCGCCAAGGCGAATATCACCATGGATGCGGGGCTGCTGGCAGCCATCGACCA
GACGGCGAAGGCGCGCGGGCTGACCCGCTCGGCCTTCCTGGCCGATCTGGCGCGGCGCGAGATCATCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References