Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 844588..845175 Replicon chromosome
Accession NZ_CP020384
Organism Rhodovulum sp. MB263

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag B5V46_RS04045 Protein ID WP_080615408.1
Coordinates 844588..844878 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag B5V46_RS04050 Protein ID WP_080615410.1
Coordinates 844888..845175 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5V46_RS04020 839768..840448 + 681 WP_080615405.1 cell wall hydrolase -
B5V46_RS04025 840545..841495 + 951 WP_080617940.1 dihydroneopterin aldolase -
B5V46_RS04030 841535..842554 + 1020 WP_080615406.1 dihydropteroate synthase -
B5V46_RS04035 842547..843890 + 1344 WP_080615407.1 phosphoglucosamine mutase -
B5V46_RS04040 843945..844199 + 255 Protein_815 transposase family protein -
B5V46_RS04045 844588..844878 + 291 WP_080615408.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B5V46_RS04050 844888..845175 + 288 WP_080615410.1 putative addiction module antidote protein Antitoxin
B5V46_RS04055 845333..846481 - 1149 WP_080615412.1 hypothetical protein -
B5V46_RS04060 846667..846918 - 252 WP_080615413.1 hypothetical protein -
B5V46_RS04065 847032..847241 - 210 WP_196774329.1 hypothetical protein -
B5V46_RS04070 847328..847960 + 633 WP_080615417.1 helix-turn-helix transcriptional regulator -
B5V46_RS04075 848094..848690 + 597 WP_080615419.1 hypothetical protein -
B5V46_RS04080 848690..849760 + 1071 WP_080615420.1 XRE family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 820929..886675 65746


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10895.67 Da        Isoelectric Point: 10.0301

>T74554 WP_080615408.1 NZ_CP020384:844588-844878 [Rhodovulum sp. MB263]
MGYEIHQSAEFSKWLRKLKDRTAQARIAIRIARLEAGLMGDAKFFDGIGELRITYGPGYRVYFVQQGETIIILLCGGDKG
SQRRDIEKAKTMAKEI

Download         Length: 291 bp

>T74554 NZ_CP020384:844588-844878 [Rhodovulum sp. MB263]
ATGGGTTACGAAATTCACCAGTCCGCCGAGTTCTCGAAATGGCTTCGCAAGCTGAAAGACCGCACGGCGCAAGCCCGCAT
CGCGATCAGGATCGCCCGGCTTGAAGCTGGCCTCATGGGCGACGCCAAGTTCTTCGACGGCATTGGTGAACTTCGGATCA
CCTACGGCCCGGGATACCGCGTCTACTTCGTCCAGCAGGGCGAGACGATCATCATCCTGCTCTGCGGAGGCGACAAAGGC
TCCCAGCGCCGGGACATCGAAAAGGCCAAGACCATGGCCAAGGAAATTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10051.47 Da        Isoelectric Point: 5.6939

>AT74554 WP_080615410.1 NZ_CP020384:844888-845175 [Rhodovulum sp. MB263]
MPIETTRFDAAEYLDTPEAQAMLLSDAFETGDAAYIKHAIGIVARARGIKDTAEAAGITREALHRALGEKGNPRLSTILG
VTKALGLTLRVEAAS

Download         Length: 288 bp

>AT74554 NZ_CP020384:844888-845175 [Rhodovulum sp. MB263]
ATGCCTATCGAAACTACCCGCTTCGACGCAGCCGAATATCTCGACACGCCGGAAGCGCAAGCGATGCTGCTCTCCGACGC
CTTCGAGACGGGTGACGCCGCCTACATCAAGCACGCCATCGGGATCGTCGCCAGGGCGCGCGGGATCAAGGACACGGCCG
AGGCCGCCGGGATCACCCGGGAGGCGCTGCACCGCGCCTTGGGTGAGAAGGGAAACCCGAGGCTGTCTACTATCCTCGGC
GTGACGAAGGCGCTCGGGCTGACGTTGCGGGTTGAAGCCGCTTCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References