Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 844588..845175 Replicon chromosome
Accession NZ_CP020384
Organism Rhodovulum sp. MB263

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag B5V46_RS04045 Protein ID WP_080615408.1
Coordinates 844588..844878 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag B5V46_RS04050 Protein ID WP_080615410.1
Coordinates 844888..845175 (+) Length 96 a.a.

Genomic Context

B5V46_RS04020B5V46_RS04025B5V46_RS04030B5V46_RS04035B5V46_RS04040B5V46_RS04045B5V46_RS04050B5V46_RS04070B5V46_RS04075B5V46_RS04080B5V46_RS04055B5V46_RS04060B5V46_RS04065
Location: 839768..840448 (681 bp)
Type: Others
Protein ID: WP_080615405.1
Location: 840545..841495 (951 bp)
Type: Others
Protein ID: WP_080617940.1
Location: 841535..842554 (1020 bp)
Type: Others
Protein ID: WP_080615406.1
Location: 842547..843890 (1344 bp)
Type: Others
Protein ID: WP_080615407.1
Location: 843945..844199 (255 bp)
Type: Others
Protein ID: Protein_815
Location: 844588..844878 (291 bp)
Type: Toxin
Protein ID: WP_080615408.1
Location: 844888..845175 (288 bp)
Type: Antitoxin
Protein ID: WP_080615410.1
Location: 847328..847960 (633 bp)
Type: Others
Protein ID: WP_080615417.1
Location: 848094..848690 (597 bp)
Type: Others
Protein ID: WP_080615419.1
Location: 848690..849760 (1071 bp)
Type: Others
Protein ID: WP_080615420.1
Location: 845333..846481 (1149 bp)
Type: Others
Protein ID: WP_080615412.1
Location: 846667..846918 (252 bp)
Type: Others
Protein ID: WP_080615413.1
Location: 847032..847241 (210 bp)
Type: Others
Protein ID: WP_196774329.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B5V46_RS04020839768..840448+681WP_080615405.1cell wall hydrolase-
B5V46_RS04025840545..841495+951WP_080617940.1dihydroneopterin aldolase-
B5V46_RS04030841535..842554+1020WP_080615406.1dihydropteroate synthase-
B5V46_RS04035842547..843890+1344WP_080615407.1phosphoglucosamine mutase-
B5V46_RS04040843945..844199+255Protein_815transposase family protein-
B5V46_RS04045844588..844878+291WP_080615408.1type II toxin-antitoxin system RelE/ParE family toxinToxin
B5V46_RS04050844888..845175+288WP_080615410.1putative addiction module antidote proteinAntitoxin
B5V46_RS04055845333..846481-1149WP_080615412.1hypothetical protein-
B5V46_RS04060846667..846918-252WP_080615413.1hypothetical protein-
B5V46_RS04065847032..847241-210WP_196774329.1hypothetical protein-
B5V46_RS04070847328..847960+633WP_080615417.1helix-turn-helix transcriptional regulator-
B5V46_RS04075848094..848690+597WP_080615419.1hypothetical protein-
B5V46_RS04080848690..849760+1071WP_080615420.1XRE family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--820929..88667565746


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10895.67 Da        Isoelectric Point: 10.0301

>T74554 WP_080615408.1 NZ_CP020384:844588-844878 [Rhodovulum sp. MB263]
MGYEIHQSAEFSKWLRKLKDRTAQARIAIRIARLEAGLMGDAKFFDGIGELRITYGPGYRVYFVQQGETIIILLCGGDKG
SQRRDIEKAKTMAKEI

Download         Length: 291 bp

>T74554 NZ_CP020384:844588-844878 [Rhodovulum sp. MB263]
ATGGGTTACGAAATTCACCAGTCCGCCGAGTTCTCGAAATGGCTTCGCAAGCTGAAAGACCGCACGGCGCAAGCCCGCAT
CGCGATCAGGATCGCCCGGCTTGAAGCTGGCCTCATGGGCGACGCCAAGTTCTTCGACGGCATTGGTGAACTTCGGATCA
CCTACGGCCCGGGATACCGCGTCTACTTCGTCCAGCAGGGCGAGACGATCATCATCCTGCTCTGCGGAGGCGACAAAGGC
TCCCAGCGCCGGGACATCGAAAAGGCCAAGACCATGGCCAAGGAAATTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10051.47 Da        Isoelectric Point: 5.6939

>AT74554 WP_080615410.1 NZ_CP020384:844888-845175 [Rhodovulum sp. MB263]
MPIETTRFDAAEYLDTPEAQAMLLSDAFETGDAAYIKHAIGIVARARGIKDTAEAAGITREALHRALGEKGNPRLSTILG
VTKALGLTLRVEAAS

Download         Length: 288 bp

>AT74554 NZ_CP020384:844888-845175 [Rhodovulum sp. MB263]
ATGCCTATCGAAACTACCCGCTTCGACGCAGCCGAATATCTCGACACGCCGGAAGCGCAAGCGATGCTGCTCTCCGACGC
CTTCGAGACGGGTGACGCCGCCTACATCAAGCACGCCATCGGGATCGTCGCCAGGGCGCGCGGGATCAAGGACACGGCCG
AGGCCGCCGGGATCACCCGGGAGGCGCTGCACCGCGCCTTGGGTGAGAAGGGAAACCCGAGGCTGTCTACTATCCTCGGC
GTGACGAAGGCGCTCGGGCTGACGTTGCGGGTTGAAGCCGCTTCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References