Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-chpS/PRK09907-MazE
Location 8268..8851 Replicon plasmid pSTH1
Accession NZ_CP020374
Organism Shewanella khirikhana strain TH2012

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag STH12_RS21120 Protein ID WP_126169620.1
Coordinates 8522..8851 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag STH12_RS21115 Protein ID WP_126169619.1
Coordinates 8268..8522 (+) Length 85 a.a.

Genomic Context

STH12_RS21090STH12_RS21095STH12_RS21100STH12_RS21105STH12_RS21110STH12_RS21115STH12_RS21120STH12_RS21125STH12_RS21130STH12_RS21140STH12_RS21145STH12_RS21150STH12_RS21135STH12_RS21155STH12_RS21160
Location: 4394..5425 (1032 bp)
Type: Others
Protein ID: WP_126169615.1
Location: 5658..6023 (366 bp)
Type: Others
Protein ID: WP_126169667.1
Location: 6032..6544 (513 bp)
Type: Others
Protein ID: WP_126169616.1
Location: 6541..7506 (966 bp)
Type: Others
Protein ID: WP_126169617.1
Location: 7518..8195 (678 bp)
Type: Others
Protein ID: WP_126169618.1
Location: 8268..8522 (255 bp)
Type: Antitoxin
Protein ID: WP_126169619.1
Location: 8522..8851 (330 bp)
Type: Toxin
Protein ID: WP_126169620.1
Location: 8953..9948 (996 bp)
Type: Others
Protein ID: WP_126169621.1
Location: 10011..10679 (669 bp)
Type: Others
Protein ID: WP_126169622.1
Location: 11360..11851 (492 bp)
Type: Others
Protein ID: WP_126169669.1
Location: 11876..12127 (252 bp)
Type: Others
Protein ID: WP_126169623.1
Location: 12099..13007 (909 bp)
Type: Others
Protein ID: WP_126169624.1
Location: 10866..11231 (366 bp)
Type: Others
Protein ID: WP_126169668.1
Location: 13052..13435 (384 bp)
Type: Others
Protein ID: WP_126169625.1
Location: 13446..13745 (300 bp)
Type: Others
Protein ID: WP_126169626.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
STH12_RS210904394..5425+1032WP_126169615.1hypothetical protein-
STH12_RS210955658..6023+366WP_126169667.1type II secretion system protein-
STH12_RS211006032..6544+513WP_126169616.1hypothetical protein-
STH12_RS211056541..7506+966WP_126169617.1hypothetical protein-
STH12_RS211107518..8195+678WP_126169618.1hypothetical protein-
STH12_RS211158268..8522+255WP_126169619.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
STH12_RS211208522..8851+330WP_126169620.1type II toxin-antitoxin system PemK/MazF family toxinToxin
STH12_RS211258953..9948+996WP_126169621.1trypsin-like serine protease-
STH12_RS2113010011..10679+669WP_126169622.1hypothetical protein-
STH12_RS2113510866..11231-366WP_126169668.1hypothetical protein-
STH12_RS2114011360..11851+492WP_126169669.1conjugative transfer signal peptidase TraF-
STH12_RS2114511876..12127+252WP_126169623.1hypothetical protein-
STH12_RS2115012099..13007+909WP_126169624.1hypothetical protein-
STH12_RS2115513052..13435-384WP_126169625.1DNA-binding protein-
STH12_RS2116013446..13745-300WP_126169626.1type II toxin-antitoxin system HigB family toxin-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..5036950369


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-107)

Antitoxin

SpoVT-AbrB domain

(6-45)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11984.94 Da        Isoelectric Point: 9.6566

>T74460 WP_126169620.1 NZ_CP020374:8522-8851 [Shewanella khirikhana]
MSYTPKRGDIVWVDFDPSAGHEQAHHRPALVLSPEPFNKQIQLALVAPITSRVRGHGFEVAVDTDKTKGVVLCQQVKTID
YAARGIKFIEKAPVAVLNEVLAKVRVLVS

Download         Length: 330 bp

>T74460 NZ_CP020374:8522-8851 [Shewanella khirikhana]
ATGAGTTACACCCCAAAGCGAGGCGACATTGTTTGGGTCGATTTTGATCCATCAGCGGGGCACGAGCAGGCGCATCATCG
TCCCGCTCTGGTGCTGTCGCCCGAGCCGTTCAACAAGCAAATTCAACTTGCTCTAGTCGCTCCCATTACCTCCAGAGTAA
GGGGGCATGGTTTCGAGGTGGCTGTAGATACCGATAAGACCAAAGGTGTTGTTTTGTGTCAACAAGTCAAGACTATTGAC
TATGCGGCAAGGGGCATCAAGTTTATCGAAAAAGCCCCGGTTGCGGTGCTAAATGAAGTGCTTGCAAAAGTGCGAGTGTT
GGTCAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8921.16 Da        Isoelectric Point: 4.3021

>AT74460 WP_126169619.1 NZ_CP020374:8268-8522 [Shewanella khirikhana]
MQTSIKKWGNSAGAIIPAAVLKKAGFGMGDQVEIEVVQGRIVMSPATPTFTLDELLNASPKGAFELDSEDTQWLSSSPVG
KEEI

Download         Length: 255 bp

>AT74460 NZ_CP020374:8268-8522 [Shewanella khirikhana]
ATGCAAACCAGCATCAAAAAATGGGGTAACTCTGCCGGAGCAATTATTCCTGCTGCCGTGTTAAAGAAGGCCGGATTCGG
TATGGGGGATCAAGTTGAAATAGAGGTTGTCCAAGGGCGTATTGTGATGAGCCCTGCAACCCCTACCTTCACTCTTGATG
AATTGCTCAATGCCAGTCCGAAAGGGGCTTTTGAACTTGATTCAGAAGATACTCAATGGCTGAGTTCGTCACCTGTCGGC
AAGGAAGAAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References