Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3054914..3055626 Replicon chromosome
Accession NZ_CP020370
Organism Candidatus Thiodictyon syntrophicum strain Cad16T

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag THSYN_RS12930 Protein ID WP_100919515.1
Coordinates 3055138..3055626 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag THSYN_RS12925 Protein ID WP_100919514.1
Coordinates 3054914..3055138 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
THSYN_RS12905 3050405..3051271 + 867 WP_100919510.1 ATPase -
THSYN_RS12910 3051480..3052562 + 1083 WP_100919511.1 homoserine O-succinyltransferase -
THSYN_RS12915 3052699..3053256 + 558 WP_172965272.1 sugar O-acetyltransferase -
THSYN_RS12920 3053259..3054689 - 1431 WP_100919513.1 FAD-dependent oxidoreductase -
THSYN_RS12925 3054914..3055138 + 225 WP_100919514.1 DUF2384 domain-containing protein Antitoxin
THSYN_RS12930 3055138..3055626 + 489 WP_100919515.1 RES family NAD+ phosphorylase Toxin
THSYN_RS12935 3055764..3057344 + 1581 WP_100919516.1 peptide chain release factor 3 -
THSYN_RS12940 3057988..3058203 + 216 WP_100922406.1 ferrous iron transport protein A -
THSYN_RS12945 3058200..3060560 + 2361 WP_100919517.1 Fe(2+) transporter permease subunit FeoB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(21-71)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 16761.07 Da        Isoelectric Point: 5.7087

>T74442 WP_100919515.1 NZ_CP020370:3055138-3055626 [Candidatus Thiodictyon syntrophicum]
MRVYRLVKERYAASALDGSGARTFGGRWNSPGTAVIYASESVALAALGLLVHLGRGEVLDSYRLFTLTLPDQAILTLDDA
ALPADWRADPAPRGIADIGDGWVASGRSAALLLPSAIIPRERNCLLNPAHPQFAAIAAAVADEPFGLDPRLAGGAASASG
VG

Download         Length: 489 bp

>T74442 NZ_CP020370:3055138-3055626 [Candidatus Thiodictyon syntrophicum]
ATGCGGGTCTATCGCCTGGTTAAGGAGCGCTATGCCGCGTCCGCCCTGGACGGCAGCGGCGCCCGGACCTTCGGTGGGCG
CTGGAACAGCCCCGGCACGGCCGTGATCTACGCCTCCGAGAGTGTTGCGCTTGCTGCCCTGGGGTTGCTGGTCCATCTGG
GCCGCGGCGAGGTCTTGGACAGCTATCGCCTCTTCACGCTGACCCTGCCGGATCAGGCCATCCTGACCTTGGATGACGCC
GCCCTGCCGGCCGACTGGCGCGCCGATCCCGCGCCGCGCGGCATCGCCGACATTGGCGACGGCTGGGTCGCGTCCGGCCG
CTCGGCCGCGTTGCTGTTGCCGAGCGCCATCATCCCGCGAGAGCGCAATTGCCTGCTGAACCCAGCCCATCCGCAGTTTG
CGGCCATCGCGGCCGCTGTCGCCGACGAGCCCTTCGGCCTCGATCCGCGCCTGGCCGGTGGGGCGGCGTCCGCGAGTGGT
GTCGGTTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8120.24 Da        Isoelectric Point: 8.5180

>AT74442 WP_100919514.1 NZ_CP020370:3054914-3055138 [Candidatus Thiodictyon syntrophicum]
MRLSAAESDRVYRIAAAFEDAVRLFEGDQAAARAWLKAPAKALGGQPPLEYLRTETGAAEVRRLIGRLEQGVYT

Download         Length: 225 bp

>AT74442 NZ_CP020370:3054914-3055138 [Candidatus Thiodictyon syntrophicum]
ATGCGGCTGTCCGCGGCCGAGAGCGATCGGGTCTATCGCATTGCCGCCGCCTTTGAAGATGCCGTGCGGCTGTTCGAGGG
CGACCAAGCCGCGGCCCGTGCCTGGCTCAAGGCGCCGGCCAAGGCCCTGGGGGGACAGCCGCCGCTTGAGTACCTGCGTA
CCGAAACCGGAGCGGCCGAGGTGCGCCGTCTGATCGGCCGACTGGAGCAGGGTGTCTACACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References