Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1850974..1851245 Replicon chromosome
Accession NZ_CP020368
Organism Escherichia coli strain BLR(DE3)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1851012..1851115 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1850974..1851245 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5762_RS09795 1848131..1849570 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
B5762_RS09800 1849688..1849924 + 237 WP_001295499.1 DUF1480 family protein -
B5762_RS09805 1850029..1850220 + 192 WP_001296140.1 YebW family protein -
B5762_RS09810 1850221..1850877 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1850974..1851245 + 272 - - Antitoxin
- 1851012..1851115 - 104 - - Toxin
B5762_RS09815 1851272..1851613 - 342 WP_000976472.1 YebY family protein -
B5762_RS09820 1851626..1852498 - 873 WP_000879293.1 copper homeostasis membrane protein CopD -
B5762_RS09825 1852502..1852876 - 375 WP_000168747.1 CopC domain-containing protein YobA -
B5762_RS09830 1853015..1853245 + 231 WP_000916763.1 DNA polymerase III subunit theta -
B5762_RS09835 1853347..1854003 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
B5762_RS09840 1854027..1854689 + 663 WP_000944245.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T74424 NZ_CP020368:c1851115-1851012 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT74424 NZ_CP020368:1850974-1851245 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References