Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4356989..4357572 Replicon chromosome
Accession NZ_CP020350
Organism Pectobacterium brasiliense strain SX309

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B5S52_RS19515 Protein ID WP_039499278.1
Coordinates 4356989..4357294 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B5S52_RS19520 Protein ID WP_039499276.1
Coordinates 4357282..4357572 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5S52_RS19500 4353405..4354364 + 960 WP_039279295.1 ABC transporter permease -
B5S52_RS19505 4354357..4355223 + 867 WP_010285293.1 ABC transporter permease -
B5S52_RS19510 4355220..4356929 + 1710 WP_039499280.1 ABC transporter ATP-binding protein -
B5S52_RS19515 4356989..4357294 - 306 WP_039499278.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B5S52_RS19520 4357282..4357572 - 291 WP_039499276.1 ribbon-helix-helix protein, CopG family Antitoxin
B5S52_RS19525 4357634..4358488 - 855 WP_039499272.1 helix-turn-helix domain-containing protein -
B5S52_RS19530 4358513..4359352 - 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
B5S52_RS19535 4359689..4361179 + 1491 WP_039510161.1 rhamnulokinase -
B5S52_RS19540 4361176..4362438 + 1263 WP_010285282.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11576.44 Da        Isoelectric Point: 9.8325

>T74344 WP_039499278.1 NZ_CP020350:c4357294-4356989 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLAALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T74344 NZ_CP020350:c4357294-4356989 [Pectobacterium brasiliense]
ATGCCACAAGTGATTGTTTCAGAACGCGCAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGCGGCATTCGTCAGTTAGCAGCGCTGCCGAATATCGGGCGACCCGTTG
AACACCTCCCCCTTGAATATCAGGAGCTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGTCATGATGAA
CTGACTGACAGAGTGGTGATACTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11074.19 Da        Isoelectric Point: 4.9616

>AT74344 WP_039499276.1 NZ_CP020350:c4357572-4357282 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQHRKEALAAWEEYQSTGEHITADEMVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT74344 NZ_CP020350:c4357572-4357282 [Pectobacterium brasiliense]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGCTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGCACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAGCACCGGCGAACACATCACCGCCGATGAGATGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References