74343

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4295378..4297076 Replicon chromosome
Accession NZ_CP020350
Organism Pectobacterium brasiliense strain SX309

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag B5S52_RS19260 Protein ID WP_040032619.1
Coordinates 4296147..4297076 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag B5S52_RS19255 Protein ID WP_040032620.1
Coordinates 4295378..4296160 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5S52_RS19235 4290401..4291354 + 954 WP_205939773.1 DUF4868 domain-containing protein -
B5S52_RS19240 4291493..4293214 - 1722 WP_080164063.1 DUF87 domain-containing protein -
B5S52_RS19245 4293225..4294238 - 1014 WP_080164065.1 SIR2 family protein -
B5S52_RS19250 4294857..4295066 - 210 WP_039510212.1 helix-turn-helix domain-containing protein -
B5S52_RS22695 4295063..4295200 - 138 WP_165572838.1 hypothetical protein -
B5S52_RS19255 4295378..4296160 + 783 WP_040032620.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
B5S52_RS19260 4296147..4297076 + 930 WP_040032619.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
B5S52_RS19265 4297458..4298360 - 903 WP_039313377.1 LysR family transcriptional regulator -
B5S52_RS19270 4298489..4298752 + 264 WP_010286385.1 DUF2798 domain-containing protein -
B5S52_RS19275 4298832..4299617 - 786 WP_174435735.1 phosphonate metabolism protein PhnP -
B5S52_RS19280 4299656..4300225 - 570 WP_039510205.1 ribose 1,5-bisphosphokinase -
B5S52_RS22530 4300228..4300368 - 141 Protein_3725 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35117.43 Da        Isoelectric Point: 5.6727

>T74343 WP_040032619.1 NZ_CP020350:4296147-4297076 [Pectobacterium brasiliense]
MDQRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGITAIQQENRADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPTKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T74343 NZ_CP020350:4296147-4297076 [Pectobacterium brasiliense]
ATGGATCAGCGTGATATTTATGCCCGACAAGTCAAGCTGTTAATGACCGCCTTGCCGTATGTGGCGAAAGAACCCTGTTT
CGCACTGAAAGGTGGCACAGCAATTAATTTATTTGTGCAGGATTTTCCTCGTCTATCGGTAGATATCGATCTGGTTTATC
AAACCTTCATAGATCGTGATACCGATCTAATCGCTATTGACGATGCATTGATGCGTATCACGGAATCGTTGAACGGCAGA
CAGGGGATCACAGCGATCCAGCAGGAGAATAGAGCCGATGAAAAACGCATCATCGTTAATACCGCTGATGCGCAGATAAA
GATTGAAGTCAGCCCGGTCTGGCGTGGGCTGCTGTTGCCCCCAGCAGAAATGCCGGTATGTGAGCAAGTGGAAATGGAAT
ACGGCTTCACCACCATGAGCGTTGTCTCTCTGGCAGATCTATACGGCGGTAAAATCTGCGCTGCGCTTGACCGCCAGCAT
CCACGCGATCTGTTTGATGTACTGAATATGCTGGAAAAACCGTGCCTGACGCGTGAGATTTTTGATGGTTTTCTTTGCTA
TCTGGCAGGACATCCTCGCCCTATTGCCGAACTGCTGGCACCGAATTGGGACACATCGCGGATCGCCACACTATACGCAC
AGGAATTTTCAGGCATGACACAGCAGGAAACCTCACTGGAATCGCTGTTATCAGTAGCGACTCTACTGCCGCAGGCGTTG
AAATCTCATTTTACCGCTCAGGACCGGCAATTCTTGCTCAGCTATAAGCAAAACAACCCTGACTGGTCGCTGTATCGCTA
TCCTGATATTCAACATCTTCCCGCCATTCGCTGGAAACAGCGTAATTTATCGGCTTTACATGCTAAAAATCCGACCAAAT
TTAGCGCGGCAGTAGGTAAGCTTGAGAAGGTTCTGGAACAACATTTTTAG

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29291.53 Da        Isoelectric Point: 9.0909

>AT74343 WP_040032620.1 NZ_CP020350:4295378-4296160 [Pectobacterium brasiliense]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLSAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLSASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGTGKRQIVPGGWLEP
DYQITVPREFKSEGIEDGSA

Download         Length: 783 bp

>AT74343 NZ_CP020350:4295378-4296160 [Pectobacterium brasiliense]
TTGACAAATTATCTAAACTGGCTGATGCAAAACACCCTGCCCGGTCAGGTGTTGCTACAGTCATGGCTTACCCGCAACGG
CATAGACCGTAAGCTCTCTTACGTCTATGTCCAAAACGGTTGGCTCAGGCGGATCGCTCACGGCGTTTACTGCCGGACGG
GTCGTGAACCAGACTGGGTGGATGCGGTTTACTGCCTGCAAACTCAATGGGAGAAACCTGTGCGGGTAGCAGGACTGACC
AGCCTTGCGCTACAGGGCTATTCCCATTATACCGAACTGGGTAAGCCTCAAATTTGGCTCACGCTCTCGGCTTATATAAA
GCTGCCGGGATGGTTCACCGCCTTTAAACCATCCGCCACCTTTGTCGTGCTCTATACATCAGGCCTGTCAGTTGATGTGA
TGCCATTCACGACAGAACTGAGAATCGGCGATCGGCGGCTGACTGGCAGCGTGCCAGAACTTGCCGCATATGAAATCGCC
AGCGGCGTTCCCGCACAAATATCGTTTGAGCATGCAGATGCATTGTTTCAGGGGCTGAACCTTCTCAGCCCGCGTAAATT
ACAGGCGCTACTCTCAGCCAGCCATTCGGTAAAAACCAACCGGGTGATGCTCTACCTTGCCCAGCGCAATGGACATCCTT
ATTTTCAATATCTCGATAAAAGTGGTATAGAAACAGGCACTGGAAAGCGGCAAATTGTCCCCGGCGGCTGGCTGGAACCG
GATTACCAGATCACGGTTCCCAGGGAGTTTAAATCGGAAGGAATCGAAGATGGATCAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References