Detailed information of TA system TA074339

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 3809841..3810877
• Replicon: chromosome
• Accession: NZ_CP020350
• Organism: Pectobacterium brasiliense strain SX309

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: B5S52_RS17000
• Protein ID: WP_039510933.1
• Coordinates: 3809841..3810416 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: B5S52_RS17005
• Protein ID: WP_039510932.1
• Coordinates: 3810416..3810877 (-)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B5S52_RS16980	3807704..3808099	-	396	WP_039510939.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
B5S52_RS16985	3808086..3808502	-	417	WP_039510935.1	YgdB family protein	-
B5S52_RS16990	3808538..3809164	-	627	WP_072035937.1	prepilin peptidase-dependent protein	-
B5S52_RS16995	3809158..3809661	-	504	WP_039276109.1	prepilin peptidase-dependent protein	-
B5S52_RS17000	3809841..3810416	-	576	WP_039510933.1	PIN domain-containing protein	Toxin
B5S52_RS17005	3810416..3810877	-	462	WP_039510932.1	helix-turn-helix domain-containing protein	Antitoxin
B5S52_RS17010	3811100..3811894	-	795	WP_039283948.1	thymidylate synthase	-
B5S52_RS17015	3811931..3812797	-	867	WP_039313946.1	prolipoprotein diacylglyceryl transferase	-
B5S52_RS17020	3813024..3815270	-	2247	WP_039283946.1	phosphoenolpyruvate--protein phosphotransferase	-
B5S52_RS17025	3815283..3815816	-	534	WP_010282870.1	RNA pyrophosphohydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• Helix-turn-helix domain, group 17 (84-132)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21465.86 Da
• Isoelectric Point: 4.7230

>T74339 WP_039510933.1 NZ_CP020350:c3810416-3809841 [Pectobacterium brasiliense]
MNHSPYPVVLDACVIYPSLLRDLLMHLGLTGLYQPKWTALIQEEWQRNLLLNNADVTMDKLRNIEHLMNKALPDANVTGF
EQLIPALVLPDADDRHVLAAAIRANAEVIVTANLKDFPATSLSEFGVEAMHPDEFIADLFDLNSALVLKAVRTSRTAFRK
PPFDVDEYLDCLLRQGLPMTVKELDAYRALI

Nucleotide

• Length: 576 bp

>T74339 NZ_CP020350:c3810416-3809841 [Pectobacterium brasiliense]
ATGAATCACTCCCCCTATCCTGTGGTACTTGATGCGTGTGTCATTTATCCATCTTTGCTACGGGATTTGCTCATGCATCT
TGGTTTAACAGGGCTATATCAGCCAAAGTGGACGGCACTAATTCAGGAAGAGTGGCAGCGAAATTTGTTGCTAAATAATG
CAGACGTAACGATGGATAAGCTCAGGAACATTGAGCATTTGATGAATAAGGCATTACCTGATGCCAATGTGACTGGGTTC
GAACAACTTATCCCTGCTCTGGTTTTACCTGATGCGGATGATCGACATGTATTGGCCGCTGCGATACGCGCTAATGCAGA
AGTTATCGTCACGGCAAATCTGAAAGATTTTCCAGCCACGTCACTTTCCGAATTTGGAGTGGAAGCCATGCACCCAGACG
AATTCATTGCCGATTTATTTGATCTCAATTCTGCACTGGTGCTTAAAGCCGTTCGAACTTCGCGAACAGCCTTCAGAAAG
CCTCCATTTGATGTGGACGAGTATCTGGATTGTCTCCTGCGTCAGGGGTTACCTATGACGGTAAAAGAACTGGATGCGTA
TCGAGCACTGATTTAA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 17293.78 Da
• Isoelectric Point: 6.2253

>AT74339 WP_039510932.1 NZ_CP020350:c3810877-3810416 [Pectobacterium brasiliense]
MKNTPLNSLSLPAPKEMEAAIRGQRQLATYLSTKLETQEISIQDAHDIAHRIELPTSALTLLMSILGELAAGNAVQIVPV
QAELTTQEAANILNVSRPHMVKLLEEGHLPFHKTGRHRRVLFSDLMQYKEQRENESMQAMQELTDRSQEFGFY

Nucleotide

• Length: 462 bp

>AT74339 NZ_CP020350:c3810877-3810416 [Pectobacterium brasiliense]
ATGAAAAATACTCCTCTAAATAGTTTGAGCCTTCCGGCTCCAAAAGAAATGGAGGCCGCTATCCGTGGACAAAGGCAGCT
TGCAACCTACCTGTCTACGAAGCTGGAAACACAGGAAATTTCGATTCAGGATGCGCACGACATTGCCCATCGGATCGAGT
TGCCTACCTCAGCACTCACGCTTTTGATGAGTATCCTTGGCGAACTGGCGGCGGGTAATGCTGTCCAGATTGTCCCTGTG
CAGGCTGAGTTAACGACACAAGAAGCGGCAAATATTCTGAATGTTTCACGGCCACATATGGTGAAGCTTTTGGAAGAAGG
CCATCTTCCTTTCCATAAAACAGGTCGTCATCGCCGCGTGCTTTTTTCTGATTTGATGCAATACAAAGAACAGCGTGAAA
ATGAAAGTATGCAAGCCATGCAGGAGCTGACAGACCGAAGTCAGGAATTCGGGTTTTACTAA