Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ataRT/DUF1778(antitoxin) |
| Location | 156539..157290 | Replicon | chromosome |
| Accession | NZ_CP020350 | ||
| Organism | Pectobacterium brasiliense strain SX309 | ||
Toxin (Protein)
| Gene name | ataT | Uniprot ID | - |
| Locus tag | B5S52_RS00700 | Protein ID | WP_155121800.1 |
| Coordinates | 156808..157290 (+) | Length | 161 a.a. |
Antitoxin (Protein)
| Gene name | ataR | Uniprot ID | A0A7V8QCC3 |
| Locus tag | B5S52_RS00695 | Protein ID | WP_039521400.1 |
| Coordinates | 156539..156817 (+) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B5S52_RS00655 | 152077..152835 | + | 759 | WP_080164249.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| B5S52_RS00660 | 152859..153188 | - | 330 | WP_080162899.1 | helix-turn-helix domain-containing protein | - |
| B5S52_RS00665 | 153139..153563 | - | 425 | Protein_130 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| B5S52_RS00670 | 154117..154767 | + | 651 | WP_080162901.1 | hypothetical protein | - |
| B5S52_RS00675 | 154702..155313 | - | 612 | WP_072038222.1 | transglycosylase domain-containing protein | - |
| B5S52_RS00680 | 155369..155560 | - | 192 | WP_039521257.1 | toxin-antitoxin system HicB family antitoxin | - |
| B5S52_RS00685 | 155691..155909 | + | 219 | Protein_134 | SymE family type I addiction module toxin | - |
| B5S52_RS00690 | 156013..156429 | + | 417 | WP_039521255.1 | hypothetical protein | - |
| B5S52_RS00695 | 156539..156817 | + | 279 | WP_039521400.1 | DUF1778 domain-containing protein | Antitoxin |
| B5S52_RS00700 | 156808..157290 | + | 483 | WP_155121800.1 | GNAT family N-acetyltransferase | Toxin |
| B5S52_RS00705 | 157423..158757 | + | 1335 | WP_039521253.1 | sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB | - |
| B5S52_RS00710 | 158830..159717 | + | 888 | WP_010281599.1 | sn-glycerol-3-phosphate ABC transporter permease UgpA | - |
| B5S52_RS00715 | 159743..160588 | + | 846 | WP_080162903.1 | sn-glycerol-3-phosphate ABC transporter permease UgpE | - |
| B5S52_RS00720 | 160614..161687 | + | 1074 | WP_010281596.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 161 a.a. Molecular weight: 17578.41 Da Isoelectric Point: 9.3652
>T74334 WP_155121800.1 NZ_CP020350:156808-157290 [Pectobacterium brasiliense]
MGITAPEPLSSRHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICAEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI
MGITAPEPLSSRHNLAEFCSQEPSLNEWLKKKALKNHSAGISRVYVICAEGTHQVIGYYCLSTGSVQRNTAPGAYRRNAP
ESLPVIVLGRLAIDQAYSGKGLGVALLKDAIFRTENIALQVGVRALVVHALDENVRNFYLKFAFDPSPVQPLMLLYPIKI
Download Length: 483 bp
>T74334 NZ_CP020350:156808-157290 [Pectobacterium brasiliense]
ATGGGAATAACTGCGCCAGAGCCATTATCTTCCAGACATAATCTTGCTGAATTTTGCAGCCAAGAACCGAGCTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATTTCTCGTGTATATGTGATTTGCGCTGAAGGCACACATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACAGCGCCTGGTGCATATAGACGTAATGCCCCC
GAATCACTACCAGTCATTGTCCTTGGGCGGCTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTGGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCGCTGGATGAGA
ACGTGCGCAATTTCTACCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCCCTGATGCTACTCTATCCAATTAAAATT
TAG
ATGGGAATAACTGCGCCAGAGCCATTATCTTCCAGACATAATCTTGCTGAATTTTGCAGCCAAGAACCGAGCTTGAATGA
ATGGCTAAAAAAGAAAGCGCTAAAAAATCATAGTGCAGGGATTTCTCGTGTATATGTGATTTGCGCTGAAGGCACACATC
AGGTGATTGGATATTATTGTTTATCAACAGGTAGCGTTCAGAGAAATACAGCGCCTGGTGCATATAGACGTAATGCCCCC
GAATCACTACCAGTCATTGTCCTTGGGCGGCTTGCCATTGATCAGGCGTATTCTGGTAAAGGTTTGGGTGTGGCTTTATT
AAAAGACGCGATATTTCGGACTGAGAATATTGCTTTGCAAGTGGGTGTGAGGGCATTAGTCGTTCACGCGCTGGATGAGA
ACGTGCGCAATTTCTACCTTAAATTCGCTTTTGATCCCTCGCCAGTGCAGCCCCTGATGCTACTCTATCCAATTAAAATT
TAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 10609.08 Da Isoelectric Point: 4.4356
>AT74334 WP_039521400.1 NZ_CP020350:156539-156817 [Pectobacterium brasiliense]
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLAELDAPITAERQAR
INDLMSRKSPWE
MKPETKEAPINIRAKASQRDLIDMAANLVSKSRTDFMLEAACREAQDILLDQRLFILDNEQFDEFLAELDAPITAERQAR
INDLMSRKSPWE
Download Length: 279 bp
>AT74334 NZ_CP020350:156539-156817 [Pectobacterium brasiliense]
ATGAAACCTGAAACTAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAACGGGATTTGATCGATATGGCTGCAAA
CCTTGTGTCAAAATCGCGTACCGATTTTATGCTTGAAGCAGCCTGCCGCGAGGCGCAGGACATTTTGTTGGATCAACGTT
TGTTTATTTTGGATAACGAACAGTTTGACGAATTTTTGGCCGAGTTGGATGCGCCTATCACCGCAGAGCGTCAGGCTCGC
ATTAACGATCTAATGAGCCGTAAATCGCCATGGGAATAA
ATGAAACCTGAAACTAAAGAAGCGCCAATCAATATTCGGGCCAAAGCCTCCCAACGGGATTTGATCGATATGGCTGCAAA
CCTTGTGTCAAAATCGCGTACCGATTTTATGCTTGAAGCAGCCTGCCGCGAGGCGCAGGACATTTTGTTGGATCAACGTT
TGTTTATTTTGGATAACGAACAGTTTGACGAATTTTTGGCCGAGTTGGATGCGCCTATCACCGCAGAGCGTCAGGCTCGC
ATTAACGATCTAATGAGCCGTAAATCGCCATGGGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|