Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1219045..1219279 | Replicon | chromosome |
| Accession | NZ_CP020339 | ||
| Organism | Shigella flexneri 4c strain 0702 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1219046..1219149 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1219045..1219279 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BS653_RS06835 | 1214478..1214945 | - | 468 | Protein_1258 | DNA-binding transcriptional regulator PgrR | - |
| BS653_RS06840 | 1215009..1215319 | + | 311 | Protein_1259 | transposase | - |
| BS653_RS06845 | 1215362..1216570 | - | 1209 | Protein_1260 | IS3 family transposase | - |
| BS653_RS06850 | 1216625..1217473 | + | 849 | Protein_1261 | IS3-like element IS600 family transposase | - |
| BS653_RS06855 | 1217590..1217871 | + | 282 | WP_005127484.1 | excisionase | - |
| BS653_RS27450 | 1217837..1218914 | + | 1078 | Protein_1263 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1219045..1219279 | + | 235 | - | - | Antitoxin |
| - | 1219046..1219149 | - | 104 | - | - | Toxin |
| BS653_RS06870 | 1219307..1219648 | - | 342 | WP_000976476.1 | YebY family protein | - |
| BS653_RS06875 | 1219661..1220533 | - | 873 | Protein_1265 | copper homeostasis membrane protein CopD | - |
| BS653_RS06880 | 1220537..1220911 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| BS653_RS06885 | 1221050..1221280 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| BS653_RS06890 | 1221382..1222038 | + | 657 | Protein_1268 | carbon-nitrogen hydrolase family protein | - |
| BS653_RS06895 | 1222062..1222724 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T74290 NZ_CP020339:c1219149-1219046 [Shigella flexneri 4c]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT74290 NZ_CP020339:1219045-1219279 [Shigella flexneri 4c]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
