74226

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 428531..428881 Replicon chromosome
Accession NZ_CP020334
Organism Xanthomonas oryzae pv. oryzae strain XM9

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag B4599_RS02150 Protein ID WP_011257368.1
Coordinates 428747..428881 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag B4599_RS02145 Protein ID WP_011407410.1
Coordinates 428531..428683 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4599_RS02115 424811..425494 - 684 WP_011257363.1 dTMP kinase -
B4599_RS02125 425974..426270 - 297 WP_012446308.1 hypothetical protein -
B4599_RS02130 426277..426516 - 240 WP_011257365.1 hypothetical protein -
B4599_RS02135 426513..427178 - 666 WP_069959695.1 hypothetical protein -
B4599_RS02140 427500..428423 + 924 WP_011407409.1 arginase -
B4599_RS02145 428531..428683 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
B4599_RS02150 428747..428881 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
B4599_RS02155 429122..429331 + 210 WP_011407411.1 CsbD family protein -
B4599_RS02160 429500..430789 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
B4599_RS02165 430842..431864 + 1023 WP_075240574.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T74226 WP_011257368.1 NZ_CP020334:428747-428881 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T74226 NZ_CP020334:428747-428881 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT74226 WP_011407410.1 NZ_CP020334:428531-428683 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT74226 NZ_CP020334:428531-428683 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References