Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2408697..2408931 | Replicon | chromosome |
| Accession | NZ_CP020106 | ||
| Organism | Escherichia coli strain 13E0780 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2408827..2408930 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2408697..2408931 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EC780_RS12830 | 2405252..2405914 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| EC780_RS12835 | 2405938..2406594 | - | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein | - |
| EC780_RS12840 | 2406696..2406926 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EC780_RS12845 | 2407065..2407439 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| EC780_RS12850 | 2407443..2408315 | + | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| EC780_RS12855 | 2408328..2408669 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2408697..2408931 | - | 235 | - | - | Antitoxin |
| - | 2408827..2408930 | + | 104 | - | - | Toxin |
| EC780_RS12860 | 2409062..2410138 | - | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| EC780_RS12865 | 2410104..2410385 | - | 282 | WP_001311878.1 | excisionase | - |
| EC780_RS12870 | 2410492..2410680 | - | 189 | WP_024165285.1 | DUF1187 family protein | - |
| - | 2410496..2410674 | + | 179 | NuclAT_0 | - | - |
| - | 2410496..2410674 | + | 179 | NuclAT_0 | - | - |
| - | 2410496..2410674 | + | 179 | NuclAT_0 | - | - |
| - | 2410496..2410674 | + | 179 | NuclAT_0 | - | - |
| EC780_RS12875 | 2410673..2410867 | - | 195 | WP_001307771.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| EC780_RS12880 | 2410899..2411579 | - | 681 | WP_000186708.1 | YqaJ viral recombinase family protein | - |
| EC780_RS12885 | 2411576..2412361 | - | 786 | WP_001484907.1 | phage recombination protein Bet | - |
| EC780_RS12890 | 2412367..2412663 | - | 297 | WP_001484906.1 | host-nuclease inhibitor protein Gam | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2401916..2453522 | 51606 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T74109 NZ_CP020106:2408827-2408930 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 235 bp
>AT74109 NZ_CP020106:c2408931-2408697 [Escherichia coli]
TAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
