Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 1433268..1433778 Replicon chromosome
Accession NZ_CP020104
Organism Spirosoma aerolatum strain KACC 17939

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag B5M13_RS05790 Protein ID WP_080054780.1
Coordinates 1433524..1433778 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B5M13_RS05785 Protein ID WP_080054779.1
Coordinates 1433268..1433522 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5M13_RS05775 1429754..1431154 - 1401 WP_080054777.1 leucine-rich repeat domain-containing protein -
B5M13_RS05780 1431359..1433206 + 1848 WP_080054778.1 ABC transporter ATP-binding protein/permease -
B5M13_RS05785 1433268..1433522 + 255 WP_080054779.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
B5M13_RS05790 1433524..1433778 + 255 WP_080054780.1 Txe/YoeB family addiction module toxin Toxin
B5M13_RS05795 1433826..1434434 + 609 WP_080054781.1 hypothetical protein -
B5M13_RS05800 1434529..1435728 + 1200 WP_080054782.1 OmpA family protein -
B5M13_RS05805 1435730..1437121 - 1392 WP_080054783.1 Gfo/Idh/MocA family oxidoreductase -
B5M13_RS05810 1437219..1438001 - 783 WP_080054784.1 NIPSNAP family protein -
B5M13_RS05815 1438311..1438649 + 339 WP_080054785.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10398.83 Da        Isoelectric Point: 7.8787

>T74098 WP_080054780.1 NZ_CP020104:1433524-1433778 [Spirosoma aerolatum]
MNLSWDKEAWEDYVYWQQTDKTVLRRINELIKECLRTPFEGKGKPEPLKENLSGFWSRRITDEHRLVYRVESDRLHIIQC
RFHY

Download         Length: 255 bp

>T74098 NZ_CP020104:1433524-1433778 [Spirosoma aerolatum]
ATGAATCTGTCGTGGGACAAAGAGGCCTGGGAGGATTATGTCTATTGGCAGCAAACGGACAAAACGGTATTGCGCCGAAT
CAATGAACTCATCAAAGAATGTCTACGGACGCCATTTGAAGGAAAAGGCAAGCCGGAACCACTGAAAGAAAACCTGAGTG
GATTCTGGTCGAGACGGATCACAGATGAGCACCGACTCGTTTACCGCGTTGAATCGGATCGTCTGCATATCATCCAATGT
CGATTCCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9788.01 Da        Isoelectric Point: 6.4710

>AT74098 WP_080054779.1 NZ_CP020104:1433268-1433522 [Spirosoma aerolatum]
MQVVNYTEFRRSMKAKLDQVSDDGDTIIINRSENKNVVLISLREYNSLKETLHLLGSEKNRNRLLGAVERANRGEFEQHQ
LIDE

Download         Length: 255 bp

>AT74098 NZ_CP020104:1433268-1433522 [Spirosoma aerolatum]
ATGCAAGTAGTTAATTATACAGAGTTTCGGCGTTCGATGAAAGCGAAGCTCGACCAGGTTAGTGACGATGGCGATACCAT
CATTATTAATCGTAGTGAGAATAAAAATGTGGTACTTATTTCCCTTCGGGAGTATAATTCGTTGAAAGAAACCTTGCATC
TGTTGGGTTCAGAGAAAAATAGAAATCGCCTTCTGGGTGCTGTTGAACGAGCGAATCGGGGTGAATTTGAACAACACCAA
CTGATTGACGAGTAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References