Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yoeB-relB/YoeB-RelB |
Location | 1433268..1433778 | Replicon | chromosome |
Accession | NZ_CP020104 | ||
Organism | Spirosoma aerolatum strain KACC 17939 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | B5M13_RS05790 | Protein ID | WP_080054780.1 |
Coordinates | 1433524..1433778 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | B5M13_RS05785 | Protein ID | WP_080054779.1 |
Coordinates | 1433268..1433522 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B5M13_RS05775 | 1429754..1431154 | - | 1401 | WP_080054777.1 | leucine-rich repeat domain-containing protein | - |
B5M13_RS05780 | 1431359..1433206 | + | 1848 | WP_080054778.1 | ABC transporter ATP-binding protein/permease | - |
B5M13_RS05785 | 1433268..1433522 | + | 255 | WP_080054779.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
B5M13_RS05790 | 1433524..1433778 | + | 255 | WP_080054780.1 | Txe/YoeB family addiction module toxin | Toxin |
B5M13_RS05795 | 1433826..1434434 | + | 609 | WP_080054781.1 | hypothetical protein | - |
B5M13_RS05800 | 1434529..1435728 | + | 1200 | WP_080054782.1 | OmpA family protein | - |
B5M13_RS05805 | 1435730..1437121 | - | 1392 | WP_080054783.1 | Gfo/Idh/MocA family oxidoreductase | - |
B5M13_RS05810 | 1437219..1438001 | - | 783 | WP_080054784.1 | NIPSNAP family protein | - |
B5M13_RS05815 | 1438311..1438649 | + | 339 | WP_080054785.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10398.83 Da Isoelectric Point: 7.8787
>T74098 WP_080054780.1 NZ_CP020104:1433524-1433778 [Spirosoma aerolatum]
MNLSWDKEAWEDYVYWQQTDKTVLRRINELIKECLRTPFEGKGKPEPLKENLSGFWSRRITDEHRLVYRVESDRLHIIQC
RFHY
MNLSWDKEAWEDYVYWQQTDKTVLRRINELIKECLRTPFEGKGKPEPLKENLSGFWSRRITDEHRLVYRVESDRLHIIQC
RFHY
Download Length: 255 bp
>T74098 NZ_CP020104:1433524-1433778 [Spirosoma aerolatum]
ATGAATCTGTCGTGGGACAAAGAGGCCTGGGAGGATTATGTCTATTGGCAGCAAACGGACAAAACGGTATTGCGCCGAAT
CAATGAACTCATCAAAGAATGTCTACGGACGCCATTTGAAGGAAAAGGCAAGCCGGAACCACTGAAAGAAAACCTGAGTG
GATTCTGGTCGAGACGGATCACAGATGAGCACCGACTCGTTTACCGCGTTGAATCGGATCGTCTGCATATCATCCAATGT
CGATTCCATTACTAA
ATGAATCTGTCGTGGGACAAAGAGGCCTGGGAGGATTATGTCTATTGGCAGCAAACGGACAAAACGGTATTGCGCCGAAT
CAATGAACTCATCAAAGAATGTCTACGGACGCCATTTGAAGGAAAAGGCAAGCCGGAACCACTGAAAGAAAACCTGAGTG
GATTCTGGTCGAGACGGATCACAGATGAGCACCGACTCGTTTACCGCGTTGAATCGGATCGTCTGCATATCATCCAATGT
CGATTCCATTACTAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9788.01 Da Isoelectric Point: 6.4710
>AT74098 WP_080054779.1 NZ_CP020104:1433268-1433522 [Spirosoma aerolatum]
MQVVNYTEFRRSMKAKLDQVSDDGDTIIINRSENKNVVLISLREYNSLKETLHLLGSEKNRNRLLGAVERANRGEFEQHQ
LIDE
MQVVNYTEFRRSMKAKLDQVSDDGDTIIINRSENKNVVLISLREYNSLKETLHLLGSEKNRNRLLGAVERANRGEFEQHQ
LIDE
Download Length: 255 bp
>AT74098 NZ_CP020104:1433268-1433522 [Spirosoma aerolatum]
ATGCAAGTAGTTAATTATACAGAGTTTCGGCGTTCGATGAAAGCGAAGCTCGACCAGGTTAGTGACGATGGCGATACCAT
CATTATTAATCGTAGTGAGAATAAAAATGTGGTACTTATTTCCCTTCGGGAGTATAATTCGTTGAAAGAAACCTTGCATC
TGTTGGGTTCAGAGAAAAATAGAAATCGCCTTCTGGGTGCTGTTGAACGAGCGAATCGGGGTGAATTTGAACAACACCAA
CTGATTGACGAGTAG
ATGCAAGTAGTTAATTATACAGAGTTTCGGCGTTCGATGAAAGCGAAGCTCGACCAGGTTAGTGACGATGGCGATACCAT
CATTATTAATCGTAGTGAGAATAAAAATGTGGTACTTATTTCCCTTCGGGAGTATAATTCGTTGAAAGAAACCTTGCATC
TGTTGGGTTCAGAGAAAAATAGAAATCGCCTTCTGGGTGCTGTTGAACGAGCGAATCGGGGTGAATTTGAACAACACCAA
CTGATTGACGAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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