Detailed information of TA system TA074073

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 2868504..2869023
• Replicon: chromosome
• Accession: NZ_CP020100
• Organism: Pseudomonas sp. S-6-2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BVH74_RS13385
• Protein ID: WP_080050548.1
• Coordinates: 2868504..2868767 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BVH74_RS13390
• Protein ID: WP_080050549.1
• Coordinates: 2868757..2869023 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BVH74_RS13360	2863836..2864474	+	639	WP_080050543.1	hypothetical protein	-
BVH74_RS13365	2864464..2865171	+	708	WP_080050544.1	class I SAM-dependent methyltransferase	-
BVH74_RS13370	2865250..2866524	-	1275	WP_080050545.1	MFS transporter	-
BVH74_RS13375	2866521..2867159	-	639	WP_080050546.1	NAD(P)H:quinone oxidoreductase	-
BVH74_RS13380	2867279..2868208	+	930	WP_080050547.1	LysR family transcriptional regulator	-
BVH74_RS13385	2868504..2868767	+	264	WP_080050548.1	BrnT family toxin	Toxin
BVH74_RS13390	2868757..2869023	+	267	WP_080050549.1	CopG family transcriptional regulator	Antitoxin
BVH74_RS13395	2869123..2871717	-	2595	WP_080051735.1	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	-
BVH74_RS13400	2872087..2872560	+	474	WP_080050550.1	DUF1289 domain-containing protein	-
BVH74_RS13405	2872610..2873470	-	861	WP_080050551.1	universal stress protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10275.68 Da
• Isoelectric Point: 7.2034

>T74073 WP_080050548.1 NZ_CP020100:2868504-2868767 [Pseudomonas sp. S-6-2]
MDEFEFDETKSQTNLDKHGIDFFTAQGLWKDPYLLEVRAKSEGEPRFLLIGKIGEKHWSAVVTYRDARIRLISVRRSRKK
EVELYEG

Nucleotide

• Length: 264 bp

>T74073 NZ_CP020100:2868504-2868767 [Pseudomonas sp. S-6-2]
ATGGATGAATTTGAGTTCGACGAAACCAAAAGTCAGACCAATCTGGATAAGCACGGTATTGATTTCTTTACTGCCCAAGG
GTTGTGGAAAGATCCGTATCTGCTGGAAGTCCGTGCAAAATCAGAGGGTGAGCCGAGGTTTTTGCTGATAGGCAAGATTG
GTGAAAAGCACTGGTCGGCTGTCGTCACATACAGGGATGCTCGTATTCGCCTTATTTCGGTAAGGCGTTCCCGCAAGAAG
GAGGTTGAGCTCTATGAAGGCTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10214.55 Da
• Isoelectric Point: 4.7411

>AT74073 WP_080050549.1 NZ_CP020100:2868757-2869023 [Pseudomonas sp. S-6-2]
MKAKDFDKKFEEDQEDVIDDLDLSSARRVNLEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESAKKPF
NGDAELPR

Nucleotide

• Length: 267 bp

>AT74073 NZ_CP020100:2868757-2869023 [Pseudomonas sp. S-6-2]
ATGAAGGCTAAAGACTTCGATAAAAAATTTGAGGAAGATCAGGAAGATGTAATTGATGACCTTGATCTTTCCTCTGCGCG
GCGTGTCAATCTGGAGCAAAAGCGAATTAACGTCGATTTCCCGGCTTGGGTCGTAGAGTCGTTGGATCGCGAGGCTGCGC
GTATTGGGGTTACCCGCCAATCTATCATCAAGGTGTGGTTGGTGGAGCGGCTGCAAGCAGAGTCTGCTAAAAAGCCGTTT
AACGGTGACGCTGAGCTTCCTCGCTAA