Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2337413..2337684 Replicon chromosome
Accession NZ_CP020092
Organism Escherichia coli strain 13E0725

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2337543..2337646 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2337413..2337684 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC725_RS12295 2333968..2334630 - 663 WP_000944256.1 exodeoxyribonuclease X -
EC725_RS12300 2334654..2335310 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
EC725_RS12305 2335412..2335642 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EC725_RS12310 2335781..2336155 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EC725_RS12315 2336159..2337031 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EC725_RS12320 2337044..2337385 + 342 WP_000976476.1 YebY family protein -
- 2337413..2337684 - 272 - - Antitoxin
- 2337543..2337646 + 104 - - Toxin
EC725_RS12325 2337781..2338437 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
EC725_RS12330 2338438..2338629 - 192 WP_001296140.1 YebW family protein -
EC725_RS12335 2338734..2338970 - 237 WP_001295499.1 DUF1480 family protein -
EC725_RS12340 2339088..2340527 - 1440 WP_001443441.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T74057 NZ_CP020092:2337543-2337646 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT74057 NZ_CP020092:c2337684-2337413 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References