Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2534626..2534860 Replicon chromosome
Accession NZ_CP020086
Organism Shigella flexneri 1a strain 0670

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2534756..2534859 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2534626..2534860 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4376_RS13510 2531181..2531843 - 663 WP_000944268.1 exodeoxyribonuclease X -
B4376_RS13515 2531867..2532523 - 657 Protein_2416 carbon-nitrogen hydrolase family protein -
B4376_RS13520 2532625..2532855 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B4376_RS13525 2532994..2533368 + 375 WP_000168747.1 CopC domain-containing protein YobA -
B4376_RS13530 2533372..2534244 + 873 Protein_2419 copper homeostasis membrane protein CopD -
B4376_RS13535 2534257..2534598 + 342 WP_000976476.1 YebY family protein -
- 2534626..2534860 - 235 - - Antitoxin
- 2534756..2534859 + 104 - - Toxin
B4376_RS28360 2534991..2536068 - 1078 Protein_2421 phage integrase Arm DNA-binding domain-containing protein -
B4376_RS13550 2536034..2536315 - 282 WP_005127484.1 excisionase -
B4376_RS13555 2536432..2537280 - 849 Protein_2423 IS3-like element IS600 family transposase -
B4376_RS13560 2537335..2538070 + 736 Protein_2424 IS3 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T74007 NZ_CP020086:2534756-2534859 [Shigella flexneri 1a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT74007 NZ_CP020086:c2534860-2534626 [Shigella flexneri 1a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References