Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 468976..469550 Replicon chromosome
Accession NZ_CP020083
Organism Blastomonas fulva strain T2

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag B5J99_RS02260 Protein ID WP_117351337.1
Coordinates 469218..469550 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag B5J99_RS02255 Protein ID WP_211337904.1
Coordinates 468976..469218 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5J99_RS02235 464399..465307 - 909 WP_162892415.1 TonB-dependent receptor -
B5J99_RS02240 465243..466883 - 1641 WP_162892416.1 TonB-dependent receptor -
B5J99_RS02245 467274..468323 + 1050 WP_117351334.1 CoA transferase -
B5J99_RS02250 468286..468765 - 480 WP_162892417.1 hypothetical protein -
B5J99_RS02255 468976..469218 + 243 WP_211337904.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
B5J99_RS02260 469218..469550 + 333 WP_117351337.1 endoribonuclease MazF Toxin
B5J99_RS02265 469557..470480 - 924 WP_117351338.1 glutaminase -
B5J99_RS02270 470580..471551 + 972 WP_117351339.1 bile acid:sodium symporter -
B5J99_RS02275 471598..472560 + 963 WP_117351340.1 radical SAM protein -
B5J99_RS02280 472637..473971 + 1335 WP_211337865.1 AarF/ABC1/UbiB kinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Antitoxin PemI-like

(1-80)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11809.71 Da        Isoelectric Point: 9.9023

>T73987 WP_117351337.1 NZ_CP020083:469218-469550 [Blastomonas fulva]
VAAYVPDAGDIVWLQFDPQAGHEQAGHRPALVLSPASYNEKRGMMICCPMTSRSKGYAFEVAVGDATGSVVLADQIKSVD
WRARKATRKGKAPVATLLDVRAKLKALLSL

Download         Length: 333 bp

>T73987 NZ_CP020083:469218-469550 [Blastomonas fulva]
GTGGCTGCCTATGTCCCGGACGCCGGTGACATCGTCTGGCTTCAGTTCGATCCGCAAGCAGGACATGAACAGGCGGGACA
CCGACCAGCTCTGGTCCTTTCGCCCGCGAGCTACAATGAAAAGCGCGGAATGATGATCTGCTGCCCGATGACATCGCGCA
GCAAGGGCTATGCTTTTGAAGTGGCTGTCGGCGATGCCACTGGCAGCGTGGTTCTGGCGGACCAGATCAAGAGTGTCGAC
TGGCGGGCACGCAAGGCCACCCGCAAGGGGAAAGCACCGGTCGCGACCCTTCTGGACGTCCGCGCCAAGCTGAAGGCGCT
GCTCAGCCTTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8861.05 Da        Isoelectric Point: 3.9823

>AT73987 WP_211337904.1 NZ_CP020083:468976-469218 [Blastomonas fulva]
MRSQVKKWGNSASVRIPARVLAAASMQIDQEVEMREEGGRIIIEPVTVPTYDLDDLLAAMAPETFPDDIDFGSPVGEEIW

Download         Length: 243 bp

>AT73987 NZ_CP020083:468976-469218 [Blastomonas fulva]
ATGCGGAGCCAAGTCAAAAAATGGGGAAACAGCGCGTCTGTTAGAATACCCGCACGGGTGCTTGCAGCGGCTTCCATGCA
GATCGATCAGGAGGTCGAAATGCGTGAGGAGGGCGGGCGGATCATCATCGAGCCGGTGACGGTCCCCACTTACGATCTGG
ATGATCTGCTTGCCGCCATGGCACCAGAGACCTTTCCCGACGATATCGATTTCGGATCACCGGTCGGCGAGGAAATCTGG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References