Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4352951..4353096 Replicon chromosome
Accession NZ_CP020067
Organism Klebsiella pneumoniae strain AR_0068

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4352987..4353089 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4352951..4353096 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM447_RS21345 4348081..4350141 + 2061 WP_004151449.1 oligopeptidase B -
AM447_RS21350 4350145..4350804 - 660 WP_043906809.1 exodeoxyribonuclease X -
AM447_RS21355 4350883..4351113 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM447_RS21360 4351226..4351600 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM447_RS21365 4351604..4352473 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM447_RS21370 4352490..4352828 + 339 WP_002911404.1 YebY family protein -
- 4352951..4353096 - 146 - - Antitoxin
- 4352987..4353089 + 103 - - Toxin
AM447_RS30895 4353465..4353608 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM447_RS21380 4353713..4354681 - 969 WP_004151446.1 VirK/YbjX family protein -
AM447_RS21385 4354838..4355491 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AM447_RS21390 4355488..4355679 - 192 WP_002911395.1 YebW family protein -
AM447_RS21395 4355777..4356016 - 240 WP_002911393.1 YebV family protein -
AM447_RS21400 4356132..4357565 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4279897..4370492 90595


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T73948 NZ_CP020067:4352987-4353089 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT73948 NZ_CP020067:c4353096-4352951 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References