Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1057794..1057895 Replicon chromosome
Accession NZ_CP020061
Organism Klebsiella pneumoniae strain AR_0117

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1057794..1057888 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1057794..1057895 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM364_RS04985 1053606..1054265 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM364_RS04990 1054344..1054574 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM364_RS04995 1054687..1055061 + 375 WP_020802218.1 CopC domain-containing protein YobA -
AM364_RS05000 1055065..1055934 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AM364_RS05005 1055951..1056289 + 339 WP_016529031.1 YebY family protein -
AM364_RS05010 1056477..1057685 - 1209 WP_001339197.1 IS4-like element ISVsa5 family transposase -
- 1057794..1057888 + 95 - - Toxin
- 1057794..1057895 - 102 - - Antitoxin
AM364_RS29270 1058263..1058406 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM364_RS05025 1058511..1059479 - 969 WP_004151446.1 VirK/YbjX family protein -
AM364_RS05030 1059636..1060289 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
AM364_RS05035 1060286..1060477 - 192 WP_002911395.1 YebW family protein -
AM364_RS05040 1060575..1060814 - 240 WP_002911393.1 YebV family protein -
AM364_RS05045 1060930..1062363 - 1434 WP_020802214.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1056477..1057685 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 95 bp

>T73921 NZ_CP020061:1057794-1057888 [Klebsiella pneumoniae]
ACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACAGGAATCGT
ATTCGGTCTCTTTTT

Antitoxin


Download         Length: 102 bp

>AT73921 NZ_CP020061:c1057895-1057794 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References