Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4770233..4770504 Replicon chromosome
Accession NZ_CP020048
Organism Escherichia coli strain AR_0118

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4770363..4770466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4770233..4770504 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM365_RS24730 4766788..4767450 - 663 WP_000944256.1 exodeoxyribonuclease X -
AM365_RS24735 4767474..4768130 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
AM365_RS24740 4768232..4768462 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AM365_RS24745 4768601..4768975 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AM365_RS24750 4768979..4769851 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
AM365_RS24755 4769864..4770205 + 342 WP_000976492.1 YebY family protein -
- 4770233..4770504 - 272 - - Antitoxin
- 4770363..4770466 + 104 - - Toxin
AM365_RS24760 4770601..4771257 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
AM365_RS24765 4771258..4771449 - 192 WP_001296140.1 YebW family protein -
AM365_RS24770 4771554..4771790 - 237 WP_001295499.1 DUF1480 family protein -
AM365_RS24775 4771908..4773347 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T73848 NZ_CP020048:4770363-4770466 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT73848 NZ_CP020048:c4770504-4770233 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References