Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3475683..3476212 Replicon chromosome
Accession NZ_CP020038
Organism Agarilytica rhodophyticola strain 017

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BVC89_RS14550 Protein ID WP_086931888.1
Coordinates 3475922..3476212 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag BVC89_RS14545 Protein ID WP_086931887.1
Coordinates 3475683..3475919 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVC89_RS14525 3471831..3473279 - 1449 WP_086931884.1 hypothetical protein -
BVC89_RS14530 3473619..3473876 + 258 WP_158657947.1 hypothetical protein -
BVC89_RS14535 3473984..3474331 + 348 WP_086934625.1 hypothetical protein -
BVC89_RS14540 3474328..3475608 + 1281 WP_086931886.1 hypothetical protein -
BVC89_RS14545 3475683..3475919 + 237 WP_086931887.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BVC89_RS14550 3475922..3476212 + 291 WP_086931888.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BVC89_RS14555 3476227..3476598 - 372 WP_086931889.1 helix-turn-helix domain-containing protein -
BVC89_RS14560 3476601..3477209 - 609 WP_086931890.1 tyrosine-type recombinase/integrase -
BVC89_RS14565 3477743..3477991 - 249 WP_158657948.1 hypothetical protein -
BVC89_RS14570 3478019..3480025 - 2007 WP_086931892.1 DEAD/DEAH box helicase family protein -
BVC89_RS14575 3479992..3480900 - 909 WP_086931893.1 DUF1837 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11324.14 Da        Isoelectric Point: 10.3790

>T73826 WP_086931888.1 NZ_CP020038:3475922-3476212 [Agarilytica rhodophyticola]
MPTYILSPQAQNSLKQISHYTRENFGEQQRKSYLKKLHTKMRAAAKEPHKGKDRSDIKAGYFSIKAEKHMIYYRIRGMHI
DIIDVLHQSMEPTLHI

Download         Length: 291 bp

>T73826 NZ_CP020038:3475922-3476212 [Agarilytica rhodophyticola]
ATGCCGACCTATATTCTCTCTCCCCAAGCGCAAAACAGCCTAAAACAAATCAGTCATTACACACGTGAAAATTTTGGTGA
ACAGCAAAGGAAATCATATCTTAAAAAGCTGCATACCAAGATGCGCGCTGCTGCAAAAGAGCCCCACAAAGGCAAAGACC
GAAGCGATATAAAGGCCGGCTATTTCAGTATCAAAGCTGAAAAGCACATGATTTATTACCGCATACGCGGCATGCATATT
GATATTATTGATGTGCTGCACCAGTCTATGGAACCCACGCTGCATATCTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8498.46 Da        Isoelectric Point: 4.4217

>AT73826 WP_086931887.1 NZ_CP020038:3475683-3475919 [Agarilytica rhodophyticola]
MARNTSVSLGDHFESFVDERVKAGRYASASDAVRAGLRLLEQEEAKLDLLRQTLATGEKQLDQGQGIDGEAFMTDLIG

Download         Length: 237 bp

>AT73826 NZ_CP020038:3475683-3475919 [Agarilytica rhodophyticola]
ATGGCTAGAAATACTAGCGTTTCACTTGGTGATCACTTTGAAAGTTTTGTTGATGAACGTGTCAAAGCTGGTCGCTATGC
GTCTGCAAGCGATGCGGTTCGCGCTGGCTTGAGGCTGCTTGAGCAAGAAGAAGCCAAGCTTGATTTACTGCGCCAAACAC
TGGCAACGGGCGAAAAGCAGCTTGATCAAGGGCAAGGCATAGACGGTGAAGCATTTATGACTGATTTGATTGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References