Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1715506..1716005 Replicon chromosome
Accession NZ_CP020017
Organism Tetragenococcus halophilus strain KUD23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B2J85_RS08220 Protein ID WP_094243812.1
Coordinates 1715506..1715775 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B2J85_RS08225 Protein ID WP_094243813.1
Coordinates 1715772..1716005 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B2J85_RS08190 1711303..1711662 + 360 WP_094244179.1 hotdog fold thioesterase -
B2J85_RS08195 1711929..1712183 - 255 WP_028790182.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
B2J85_RS08200 1712395..1713300 + 906 WP_094243809.1 ribokinase -
B2J85_RS08205 1713324..1713476 + 153 Protein_1607 D-ribose pyranase -
B2J85_RS08210 1713586..1714137 - 552 WP_094243810.1 GNAT family N-acetyltransferase -
B2J85_RS12780 1714255..1714359 + 105 WP_157728022.1 type I toxin-antitoxin system Fst family toxin -
B2J85_RS08215 1714881..1715372 - 492 WP_094243811.1 HAD hydrolase-like protein -
B2J85_RS08220 1715506..1715775 - 270 WP_094243812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B2J85_RS08225 1715772..1716005 - 234 WP_094243813.1 toxin-antitoxin system, antitoxin component Antitoxin
B2J85_RS08230 1716184..1717410 - 1227 WP_094243814.1 MFS transporter -
B2J85_RS12785 1717795..1717896 - 102 WP_157728051.1 IS3 family transposase -
B2J85_RS08235 1717994..1718194 - 201 WP_157728024.1 DDE-type integrase/transposase/recombinase -
B2J85_RS08240 1718225..1718476 - 252 WP_094243816.1 IS3 family transposase -
B2J85_RS08245 1718608..1718829 - 222 WP_094243817.1 transposase -
B2J85_RS08250 1719010..1720974 - 1965 WP_094243818.1 BglG family transcription antiterminator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10556.32 Da        Isoelectric Point: 10.7843

>T73762 WP_094243812.1 NZ_CP020017:c1715775-1715506 [Tetragenococcus halophilus]
MTFHVETTRRFDKQLKKLDNFTAKTILKWLDKNIEGVNNPRTFGKPLVGNHSGKWRYRIGDYRVITKIDDKKLIILALEV
GHRKDIYKN

Download         Length: 270 bp

>T73762 NZ_CP020017:c1715775-1715506 [Tetragenococcus halophilus]
ATGACTTTTCATGTGGAAACAACTCGTAGATTTGATAAGCAATTAAAAAAATTAGATAACTTTACTGCAAAGACTATACT
TAAGTGGCTTGATAAAAATATTGAAGGAGTTAATAACCCAAGAACTTTTGGTAAACCTTTAGTCGGAAATCATTCCGGAA
AATGGCGCTATCGAATCGGGGATTATCGTGTAATCACCAAAATAGACGATAAGAAATTGATTATTTTAGCTTTAGAAGTA
GGACATAGAAAAGATATTTATAAAAATTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8671.48 Da        Isoelectric Point: 3.8704

>AT73762 WP_094243813.1 NZ_CP020017:c1716005-1715772 [Tetragenococcus halophilus]
MATITVRVTDEEKNFLDNMAKFEGKSLSELLKTTTLSSLEDAYDAQIGDTAYEEYLRDPQSRPLSESLEEYGLGESE

Download         Length: 234 bp

>AT73762 NZ_CP020017:c1716005-1715772 [Tetragenococcus halophilus]
ATGGCTACTATTACTGTTCGTGTTACGGATGAAGAAAAAAATTTTTTAGATAATATGGCAAAGTTTGAGGGAAAAAGTTT
GTCTGAATTACTGAAAACCACGACGTTATCCTCTTTAGAAGACGCTTATGATGCACAAATTGGAGATACAGCCTATGAGG
AATACTTAAGGGATCCGCAATCTCGTCCTTTATCAGAATCACTAGAGGAGTATGGATTAGGAGAAAGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References