Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1643967..1644460 Replicon chromosome
Accession NZ_CP020017
Organism Tetragenococcus halophilus strain KUD23

Toxin (Protein)


Gene name relE Uniprot ID A0A2H6C3W3
Locus tag B2J85_RS07895 Protein ID WP_014123900.1
Coordinates 1643967..1644233 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2H6CKH8
Locus tag B2J85_RS07900 Protein ID WP_014123899.1
Coordinates 1644230..1644460 (-) Length 77 a.a.

Genomic Context


B2J85_RS07875B2J85_RS07880B2J85_RS07885B2J85_RS07890B2J85_RS07905B2J85_RS07910B2J85_RS07915B2J85_RS07865B2J85_RS07870B2J85_RS07895B2J85_RS07900
Location: 1640831..1641538 (708 bp)
Type: Others
Protein ID: WP_014123906.1
Location: 1641522..1642442 (921 bp)
Type: Others
Protein ID: WP_014123905.1
Location: 1642769..1643416 (648 bp)
Type: Others
Protein ID: WP_014123904.1
Location: 1643572..1643754 (183 bp)
Type: Others
Protein ID: WP_014123901.1
Location: 1644627..1644863 (237 bp)
Type: Others
Protein ID: WP_014123898.1
Location: 1645074..1646180 (1107 bp)
Type: Others
Protein ID: WP_094243771.1
Location: 1646496..1647698 (1203 bp)
Type: Others
Protein ID: WP_157728020.1
Location: 1640091..1640375 (285 bp)
Type: Others
Protein ID: WP_014123908.1
Location: 1640365..1640610 (246 bp)
Type: Others
Protein ID: WP_014123907.1
Location: 1643967..1644233 (267 bp)
Type: Toxin
Protein ID: WP_014123900.1
Location: 1644230..1644460 (231 bp)
Type: Antitoxin
Protein ID: WP_014123899.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B2J85_RS078651640091..1640375-285WP_014123908.1type II toxin-antitoxin system YafQ family toxin-
B2J85_RS078701640365..1640610-246WP_014123907.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
B2J85_RS078751640831..1641538+708WP_014123906.1DUF969 domain-containing protein-
B2J85_RS078801641522..1642442+921WP_014123905.1DUF979 domain-containing protein-
B2J85_RS078851642769..1643416+648WP_014123904.1pyroglutamyl-peptidase I-
B2J85_RS078901643572..1643754+183WP_014123901.1putative holin-like toxin-
B2J85_RS078951643967..1644233-267WP_014123900.1type II toxin-antitoxin system RelE/ParE family toxinToxin
B2J85_RS079001644230..1644460-231WP_014123899.1hypothetical proteinAntitoxin
B2J85_RS079051644627..1644863+237WP_014123898.1hypothetical protein-
B2J85_RS079101645074..1646180+1107WP_094243771.1Ldh family oxidoreductase-
B2J85_RS079151646496..1647698+1203WP_157728020.1divalent metal cation transporter-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10597.17 Da        Isoelectric Point: 10.0661

>T73761 WP_014123900.1 NZ_CP020017:c1644233-1643967 [Tetragenococcus halophilus]
MSYRLVFTSEIQKQFRKMDKYQATLITRWLYQHIDGIDDPRKFGKELTTNRSGQWRYRIGKYRVIVEIEDSQLVVLAVQV
GHEKNVYN

Download         Length: 267 bp

>T73761 NZ_CP020017:c1644233-1643967 [Tetragenococcus halophilus]
ATGAGCTACCGCTTAGTCTTCACTTCTGAAATACAAAAACAATTTAGAAAAATGGATAAATATCAGGCGACTTTAATTAC
TCGTTGGCTGTATCAGCATATTGATGGAATTGACGACCCTCGCAAATTTGGCAAAGAACTAACTACAAATCGGTCTGGTC
AATGGCGTTATAGAATTGGCAAATATCGTGTTATCGTTGAAATAGAAGATAGCCAATTGGTTGTACTAGCTGTTCAAGTT
GGTCATGAAAAAAATGTTTATAATTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8878.94 Da        Isoelectric Point: 3.9487

>AT73761 WP_014123899.1 NZ_CP020017:c1644460-1644230 [Tetragenococcus halophilus]
MAMITVRVSDAEKEWLNYMADFYGISLSDLLKTYSMEQLEDEYDRQTAEIAYKHWLENGKQTVSMDEILSEFGGLE

Download         Length: 231 bp

>AT73761 NZ_CP020017:c1644460-1644230 [Tetragenococcus halophilus]
ATGGCTATGATTACAGTACGTGTAAGTGACGCGGAAAAAGAATGGTTGAATTATATGGCTGATTTCTACGGAATCTCTTT
GTCTGACCTTTTAAAAACCTATTCGATGGAACAATTAGAAGATGAATATGACCGCCAAACAGCTGAGATTGCATATAAAC
ATTGGCTCGAAAATGGTAAGCAAACAGTATCAATGGATGAAATTCTTTCTGAATTTGGAGGTTTAGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2H6C3W3


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2H6CKH8

References