Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 456310..456963 Replicon chromosome
Accession NZ_CP020015
Organism Acinetobacter lactucae strain OTEC-02

Toxin (Protein)


Gene name cptA Uniprot ID R8Z3I7
Locus tag OTEC02_RS02255 Protein ID WP_016143557.1
Coordinates 456574..456963 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag OTEC02_RS02250 Protein ID WP_002117064.1
Coordinates 456310..456567 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OTEC02_RS02230 451823..452830 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
OTEC02_RS02235 452849..453226 + 378 WP_002049717.1 50S ribosomal protein L17 -
OTEC02_RS02240 453408..454898 + 1491 WP_031949423.1 NAD(P)/FAD-dependent oxidoreductase -
OTEC02_RS02245 454949..456121 - 1173 WP_016143559.1 acyl-CoA dehydrogenase family protein -
OTEC02_RS02250 456310..456567 + 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
OTEC02_RS02255 456574..456963 + 390 WP_016143557.1 hypothetical protein Toxin
OTEC02_RS02260 457734..458822 + 1089 WP_014207738.1 hypothetical protein -
OTEC02_RS02265 458907..459482 + 576 WP_031949421.1 rhombosortase -
OTEC02_RS02270 459662..461857 + 2196 WP_016143554.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15620.65 Da        Isoelectric Point: 8.7137

>T73759 WP_016143557.1 NZ_CP020015:456574-456963 [Acinetobacter lactucae]
MIKELNFELKYSRVSVIFQLFIGLGLAILLYQLLMPIWWLCAVIFIFIGFIFFLKQTQISQIEYLDQKLWSVAYYSEKEI
YRAEIRKIIDYQMFVVIYFEGTSAKATTVWFDQLSIEQWKRLKVLEKLY

Download         Length: 390 bp

>T73759 NZ_CP020015:456574-456963 [Acinetobacter lactucae]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGGTAATATTTCAGCTTTTTATTGGTTTGGGTTTAGC
AATCTTGCTTTATCAATTATTAATGCCGATATGGTGGCTATGTGCTGTCATTTTTATATTTATTGGTTTTATTTTCTTTT
TAAAGCAAACACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTACTCGGAAAAAGAAATT
TACCGTGCGGAAATTAGAAAAATAATTGATTATCAGATGTTTGTAGTGATTTATTTTGAAGGGACATCTGCGAAAGCAAC
AACTGTTTGGTTCGATCAGCTTTCTATTGAGCAGTGGAAAAGATTAAAAGTTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT73759 WP_002117064.1 NZ_CP020015:456310-456567 [Acinetobacter lactucae]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT73759 NZ_CP020015:456310-456567 [Acinetobacter lactucae]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAACTATTATTTAAAAGCTGATCCGGCAGAAAAAGCATTATTTGCAGAGTTAGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAGCCTCCACGTACTGAGTTACGTGAATTTATTTATAAATTAAAA
CAGTATGTACATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB R8Z3I7

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References