Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2437595..2438166 Replicon chromosome
Accession NZ_CP019998
Organism Arthrospira platensis C1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag APLC1_RS11850 Protein ID WP_006624723.1
Coordinates 2437825..2438166 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID B5W521
Locus tag APLC1_RS11845 Protein ID WP_006624722.1
Coordinates 2437595..2437828 (+) Length 78 a.a.

Genomic Context

APLC1_RS11795APLC1_RS11800APLC1_RS11810APLC1_RS11815APLC1_RS11840APLC1_RS11845APLC1_RS11850APLC1_RS11865APLC1_RS11870APLC1_RS11875APLC1_RS11805APLC1_RS11820APLC1_RS11825APLC1_RS11830APLC1_RS11835APLC1_RS11855APLC1_RS11860
Location: 2433439..2434269 (831 bp)
Type: Others
Protein ID: WP_006624709.1
Location: 2434357..2434509 (153 bp)
Type: Others
Protein ID: WP_228116363.1
Location: 2434796..2435008 (213 bp)
Type: Others
Protein ID: WP_006624713.1
Location: 2434995..2435402 (408 bp)
Type: Others
Protein ID: WP_006624714.1
Location: 2437150..2437428 (279 bp)
Type: Others
Protein ID: WP_006624721.1
Location: 2437595..2437828 (234 bp)
Type: Antitoxin
Protein ID: WP_006624722.1
Location: 2437825..2438166 (342 bp)
Type: Toxin
Protein ID: WP_006624723.1
Location: 2438968..2439210 (243 bp)
Type: Others
Protein ID: WP_006624726.1
Location: 2439240..2439476 (237 bp)
Type: Others
Protein ID: WP_006624727.1
Location: 2439479..2439883 (405 bp)
Type: Others
Protein ID: WP_006624728.1
Location: 2434529..2434699 (171 bp)
Type: Others
Protein ID: WP_260378917.1
Location: 2435624..2435836 (213 bp)
Type: Others
Protein ID: WP_006624715.1
Location: 2436057..2436263 (207 bp)
Type: Others
Protein ID: WP_006624717.1
Location: 2436409..2436792 (384 bp)
Type: Others
Protein ID: WP_006624719.1
Location: 2436785..2437021 (237 bp)
Type: Others
Protein ID: WP_006624720.1
Location: 2438297..2438527 (231 bp)
Type: Others
Protein ID: WP_006624724.1
Location: 2438515..2438829 (315 bp)
Type: Others
Protein ID: WP_006624725.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
APLC1_RS11795 (APLC1_2543)2433439..2434269+831WP_006624709.1nitrate ABC transporter ATP-binding protein-
APLC1_RS11800 (APLC1_2544)2434357..2434509+153WP_228116363.1hypothetical protein-
APLC1_RS118052434529..2434699-171WP_260378917.1hypothetical protein-
APLC1_RS11810 (APLC1_2545)2434796..2435008+213WP_006624713.1type II toxin-antitoxin system VapB family antitoxin-
APLC1_RS11815 (APLC1_2546)2434995..2435402+408WP_006624714.1PIN domain nuclease-
APLC1_RS11820 (APLC1_2547)2435624..2435836-213WP_006624715.1hypothetical protein-
APLC1_RS11825 (APLC1_2549)2436057..2436263-207WP_006624717.1hypothetical protein-
APLC1_RS11830 (APLC1_2550)2436409..2436792-384WP_006624719.1type II toxin-antitoxin system VapC family toxin-
APLC1_RS11835 (APLC1_2551)2436785..2437021-237WP_006624720.1hypothetical protein-
APLC1_RS118402437150..2437428+279WP_006624721.1hypothetical protein-
APLC1_RS11845 (APLC1_2552)2437595..2437828+234WP_006624722.1DUF433 domain-containing proteinAntitoxin
APLC1_RS11850 (APLC1_2553)2437825..2438166+342WP_006624723.1DUF5615 family PIN-like proteinToxin
APLC1_RS11855 (APLC1_2554)2438297..2438527-231WP_006624724.1hypothetical protein-
APLC1_RS11860 (APLC1_2555)2438515..2438829-315WP_006624725.1hypothetical protein-
APLC1_RS118652438968..2439210+243WP_006624726.1hypothetical protein-
APLC1_RS11870 (APLC1_2556)2439240..2439476+237WP_006624727.1hypothetical protein-
APLC1_RS11875 (APLC1_2557)2439479..2439883+405WP_006624728.1PIN domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(11-66)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12622.57 Da        Isoelectric Point: 4.2821

>T73679 WP_006624723.1 NZ_CP019998:2437825-2438166 [Arthrospira platensis C1]
MKIWVDAQLPPTLASWLTETFGLEASALRDLGWRDAQDIEIFAAARSENVVIVTKDSDFIDLVCRLGSPPQILWLTCGNV
TNRNLRKLLMATLPNALEQLQQGEMIVEITNTP

Download         Length: 342 bp

>T73679 NZ_CP019998:2437825-2438166 [Arthrospira platensis C1]
ATGAAAATTTGGGTCGATGCTCAACTTCCGCCTACGTTGGCAAGTTGGCTGACAGAAACCTTTGGTTTAGAAGCGAGTGC
ATTGCGGGATTTAGGCTGGCGGGATGCTCAAGATATCGAGATTTTTGCAGCAGCACGGTCTGAAAATGTGGTGATTGTCA
CGAAAGACAGTGATTTTATTGATTTGGTCTGTCGTTTAGGATCGCCTCCTCAAATTTTATGGCTAACTTGTGGCAATGTC
ACGAACCGTAATTTGCGAAAATTGTTAATGGCAACTTTACCGAATGCGTTGGAGCAATTGCAGCAAGGAGAAATGATTGT
GGAAATTACGAATACGCCTTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8595.96 Da        Isoelectric Point: 4.4644

>AT73679 WP_006624722.1 NZ_CP019998:2437595-2437828 [Arthrospira platensis C1]
MTSTPELMSRITQNPGQCGGRPCIRGMRIRVTDILEMLAENVSISEVLEDFPDLELADIQACLLFAARRTDFPRLTA

Download         Length: 234 bp

>AT73679 NZ_CP019998:2437595-2437828 [Arthrospira platensis C1]
ATGACTTCAACTCCTGAATTAATGAGCCGAATTACGCAAAATCCCGGTCAATGTGGGGGTCGTCCCTGTATTCGCGGGAT
GCGAATTAGAGTCACCGATATTTTAGAAATGTTAGCGGAAAATGTGAGCATTTCTGAAGTTTTAGAAGATTTTCCCGATT
TAGAACTAGCAGATATTCAAGCCTGTCTGCTGTTTGCGGCAAGACGTACTGATTTTCCCAGACTCACCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7G7VPN8

References