Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 462566..463265 Replicon chromosome
Accession NZ_CP019998
Organism Arthrospira platensis C1

Toxin (Protein)


Gene name tad Uniprot ID A0A9J7AZD3
Locus tag APLC1_RS02365 Protein ID WP_006622793.1
Coordinates 462894..463265 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag APLC1_RS02360 Protein ID WP_006622792.1
Coordinates 462566..462889 (-) Length 108 a.a.

Genomic Context

APLC1_RS02305APLC1_RS02315APLC1_RS02320APLC1_RS02325APLC1_RS02330APLC1_RS02350APLC1_RS02355APLC1_RS02370APLC1_RS02380APLC1_RS02385APLC1_RS02395APLC1_RS02400APLC1_RS02310APLC1_RS02335APLC1_RS02340APLC1_RS02345APLC1_RS02360APLC1_RS02365APLC1_RS02375APLC1_RS02390
Location: 457868..458575 (708 bp)
Type: Others
Protein ID: WP_006668943.1
Location: 459169..459297 (129 bp)
Type: Others
Protein ID: WP_008056050.1
Location: 459340..459495 (156 bp)
Type: Others
Protein ID: WP_006622779.1
Location: 459492..459650 (159 bp)
Type: Others
Protein ID: WP_006622780.1
Location: 459699..459854 (156 bp)
Type: Others
Protein ID: WP_006622781.1
Location: 461763..462125 (363 bp)
Type: Others
Protein ID: WP_006622789.1
Location: 462085..462375 (291 bp)
Type: Others
Protein ID: WP_006622790.1
Location: 463350..463466 (117 bp)
Type: Others
Protein ID: Protein_470
Location: 465189..466061 (873 bp)
Type: Others
Protein ID: WP_006622797.1
Location: 466220..466750 (531 bp)
Type: Others
Protein ID: WP_006622798.1
Location: 467378..467545 (168 bp)
Type: Others
Protein ID: WP_006622800.1
Location: 467598..467864 (267 bp)
Type: Others
Protein ID: WP_006622801.1
Location: 458674..458925 (252 bp)
Type: Others
Protein ID: WP_006622777.1
Location: 460107..460328 (222 bp)
Type: Others
Protein ID: WP_006622783.1
Location: 460331..460531 (201 bp)
Type: Others
Protein ID: WP_231296472.1
Location: 460787..461023 (237 bp)
Type: Others
Protein ID: WP_192808262.1
Location: 462566..462889 (324 bp)
Type: Antitoxin
Protein ID: WP_006622792.1
Location: 462894..463265 (372 bp)
Type: Toxin
Protein ID: WP_006622793.1
Location: 463950..464804 (855 bp)
Type: Others
Protein ID: WP_051164802.1
Location: 466700..467353 (654 bp)
Type: Others
Protein ID: WP_006622799.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
APLC1_RS02305 (APLC1_0483)457868..458575+708WP_006668943.1hypothetical protein-
APLC1_RS02310 (APLC1_0484)458674..458925-252WP_006622777.1hypothetical protein-
APLC1_RS02315459169..459297+129WP_008056050.1hypothetical protein-
APLC1_RS02320 (APLC1_0485)459340..459495+156WP_006622779.1hypothetical protein-
APLC1_RS02325 (APLC1_0486)459492..459650+159WP_006622780.1hypothetical protein-
APLC1_RS02330 (APLC1_0487)459699..459854+156WP_006622781.1hypothetical protein-
APLC1_RS02335 (APLC1_0488)460107..460328-222WP_006622783.1hypothetical protein-
APLC1_RS02340460331..460531-201WP_231296472.1type II toxin-antitoxin system HigB family toxin-
APLC1_RS02345460787..461023-237WP_192808262.1hypothetical protein-
APLC1_RS02350 (APLC1_0490)461763..462125+363WP_006622789.1hypothetical protein-
APLC1_RS02355 (APLC1_0491)462085..462375+291WP_006622790.1hypothetical protein-
APLC1_RS02360 (APLC1_0492)462566..462889-324WP_006622792.1helix-turn-helix transcriptional regulatorAntitoxin
APLC1_RS02365 (APLC1_0493)462894..463265-372WP_006622793.1type II toxin-antitoxin system RelE/ParE family toxinToxin
APLC1_RS02370 (APLC1_0494)463350..463466+117Protein_470type II toxin-antitoxin system HicB family antitoxin-
APLC1_RS02375 (APLC1_0495)463950..464804-855WP_051164802.1hypothetical protein-
APLC1_RS02380 (APLC1_0496)465189..466061+873WP_006622797.1polysaccharide pyruvyl transferase family protein-
APLC1_RS02385 (APLC1_0498)466220..466750+531WP_006622798.1DUF1998 domain-containing protein-
APLC1_RS02390 (APLC1_0499)466700..467353-654WP_006622799.1cation diffusion facilitator family transporter-
APLC1_RS02395467378..467545+168WP_006622800.1hypothetical protein-
APLC1_RS02400 (APLC1_0500)467598..467864+267WP_006622801.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13866.86 Da        Isoelectric Point: 6.8723

>T73674 WP_006622793.1 NZ_CP019998:c463265-462894 [Arthrospira platensis C1]
MSELLKPVEWVGSSLEDLKEFPEEVRQGVGYALYLAQCGEKHPSAKPLKGFKGAGVLEVVEDFDGDTYRAVYTLKLAGVV
YVLHAFQKKSQKGIATPKQDIELIEGRLKRAKEHYSEHYINQQ

Download         Length: 372 bp

>T73674 NZ_CP019998:c463265-462894 [Arthrospira platensis C1]
ATGAGTGAATTACTAAAACCAGTTGAGTGGGTTGGCAGTTCTCTTGAGGATTTAAAAGAGTTCCCGGAGGAGGTTCGGCA
AGGTGTTGGTTATGCGCTATATCTGGCTCAATGTGGTGAAAAGCACCCGTCTGCGAAACCACTCAAAGGCTTTAAGGGGG
CTGGGGTGCTTGAAGTTGTCGAAGATTTTGACGGAGACACTTATCGAGCCGTTTACACTTTAAAGTTAGCTGGGGTGGTC
TATGTCCTGCACGCTTTTCAGAAGAAGTCACAAAAAGGGATTGCCACGCCTAAGCAGGATATTGAGCTAATCGAGGGAAG
GCTTAAACGTGCCAAAGAACATTACTCCGAACATTACATCAATCAGCAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11651.47 Da        Isoelectric Point: 10.0883

>AT73674 WP_006622792.1 NZ_CP019998:c462889-462566 [Arthrospira platensis C1]
MNHPIKVQAGSGNVFADLELENSDELLVKAELARRISGIIAAQNMTQTEAAQMLGIDQPKVSALVNGKLSGFSTTRLFRF
LNALGRDVEIVVKPKSFRQAETRVVAL

Download         Length: 324 bp

>AT73674 NZ_CP019998:c462889-462566 [Arthrospira platensis C1]
ATGAATCACCCGATTAAAGTACAAGCAGGAAGTGGCAATGTATTCGCCGATTTAGAGTTAGAAAATTCTGATGAATTACT
GGTCAAGGCAGAACTTGCCCGGAGAATTAGTGGTATTATCGCCGCCCAAAATATGACTCAAACTGAGGCGGCACAAATGT
TAGGCATTGACCAGCCTAAAGTGTCAGCATTAGTGAATGGCAAGCTATCGGGTTTTTCCACTACTCGGTTGTTTCGTTTT
TTAAATGCGTTGGGTCGAGATGTGGAAATCGTAGTAAAACCCAAGTCTTTTAGACAAGCTGAAACACGAGTGGTGGCGTT
GTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References