Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 462566..463265 Replicon chromosome
Accession NZ_CP019998
Organism Arthrospira platensis C1

Toxin (Protein)


Gene name tad Uniprot ID A0A9J7AZD3
Locus tag APLC1_RS02365 Protein ID WP_006622793.1
Coordinates 462894..463265 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag APLC1_RS02360 Protein ID WP_006622792.1
Coordinates 462566..462889 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APLC1_RS02305 (APLC1_0483) 457868..458575 + 708 WP_006668943.1 hypothetical protein -
APLC1_RS02310 (APLC1_0484) 458674..458925 - 252 WP_006622777.1 hypothetical protein -
APLC1_RS02315 459169..459297 + 129 WP_008056050.1 hypothetical protein -
APLC1_RS02320 (APLC1_0485) 459340..459495 + 156 WP_006622779.1 hypothetical protein -
APLC1_RS02325 (APLC1_0486) 459492..459650 + 159 WP_006622780.1 hypothetical protein -
APLC1_RS02330 (APLC1_0487) 459699..459854 + 156 WP_006622781.1 hypothetical protein -
APLC1_RS02335 (APLC1_0488) 460107..460328 - 222 WP_006622783.1 hypothetical protein -
APLC1_RS02340 460331..460531 - 201 WP_231296472.1 type II toxin-antitoxin system HigB family toxin -
APLC1_RS02345 460787..461023 - 237 WP_192808262.1 hypothetical protein -
APLC1_RS02350 (APLC1_0490) 461763..462125 + 363 WP_006622789.1 hypothetical protein -
APLC1_RS02355 (APLC1_0491) 462085..462375 + 291 WP_006622790.1 hypothetical protein -
APLC1_RS02360 (APLC1_0492) 462566..462889 - 324 WP_006622792.1 helix-turn-helix transcriptional regulator Antitoxin
APLC1_RS02365 (APLC1_0493) 462894..463265 - 372 WP_006622793.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APLC1_RS02370 (APLC1_0494) 463350..463466 + 117 Protein_470 type II toxin-antitoxin system HicB family antitoxin -
APLC1_RS02375 (APLC1_0495) 463950..464804 - 855 WP_051164802.1 hypothetical protein -
APLC1_RS02380 (APLC1_0496) 465189..466061 + 873 WP_006622797.1 polysaccharide pyruvyl transferase family protein -
APLC1_RS02385 (APLC1_0498) 466220..466750 + 531 WP_006622798.1 DUF1998 domain-containing protein -
APLC1_RS02390 (APLC1_0499) 466700..467353 - 654 WP_006622799.1 cation diffusion facilitator family transporter -
APLC1_RS02395 467378..467545 + 168 WP_006622800.1 hypothetical protein -
APLC1_RS02400 (APLC1_0500) 467598..467864 + 267 WP_006622801.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13866.86 Da        Isoelectric Point: 6.8723

>T73674 WP_006622793.1 NZ_CP019998:c463265-462894 [Arthrospira platensis C1]
MSELLKPVEWVGSSLEDLKEFPEEVRQGVGYALYLAQCGEKHPSAKPLKGFKGAGVLEVVEDFDGDTYRAVYTLKLAGVV
YVLHAFQKKSQKGIATPKQDIELIEGRLKRAKEHYSEHYINQQ

Download         Length: 372 bp

>T73674 NZ_CP019998:c463265-462894 [Arthrospira platensis C1]
ATGAGTGAATTACTAAAACCAGTTGAGTGGGTTGGCAGTTCTCTTGAGGATTTAAAAGAGTTCCCGGAGGAGGTTCGGCA
AGGTGTTGGTTATGCGCTATATCTGGCTCAATGTGGTGAAAAGCACCCGTCTGCGAAACCACTCAAAGGCTTTAAGGGGG
CTGGGGTGCTTGAAGTTGTCGAAGATTTTGACGGAGACACTTATCGAGCCGTTTACACTTTAAAGTTAGCTGGGGTGGTC
TATGTCCTGCACGCTTTTCAGAAGAAGTCACAAAAAGGGATTGCCACGCCTAAGCAGGATATTGAGCTAATCGAGGGAAG
GCTTAAACGTGCCAAAGAACATTACTCCGAACATTACATCAATCAGCAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11651.47 Da        Isoelectric Point: 10.0883

>AT73674 WP_006622792.1 NZ_CP019998:c462889-462566 [Arthrospira platensis C1]
MNHPIKVQAGSGNVFADLELENSDELLVKAELARRISGIIAAQNMTQTEAAQMLGIDQPKVSALVNGKLSGFSTTRLFRF
LNALGRDVEIVVKPKSFRQAETRVVAL

Download         Length: 324 bp

>AT73674 NZ_CP019998:c462889-462566 [Arthrospira platensis C1]
ATGAATCACCCGATTAAAGTACAAGCAGGAAGTGGCAATGTATTCGCCGATTTAGAGTTAGAAAATTCTGATGAATTACT
GGTCAAGGCAGAACTTGCCCGGAGAATTAGTGGTATTATCGCCGCCCAAAATATGACTCAAACTGAGGCGGCACAAATGT
TAGGCATTGACCAGCCTAAAGTGTCAGCATTAGTGAATGGCAAGCTATCGGGTTTTTCCACTACTCGGTTGTTTCGTTTT
TTAAATGCGTTGGGTCGAGATGTGGAAATCGTAGTAAAACCCAAGTCTTTTAGACAAGCTGAAACACGAGTGGTGGCGTT
GTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References