Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 455414..456113 Replicon chromosome
Accession NZ_CP019998
Organism Arthrospira platensis C1

Toxin (Protein)


Gene name tad Uniprot ID B5VZQ1
Locus tag APLC1_RS02285 Protein ID WP_006622773.1
Coordinates 455742..456113 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag APLC1_RS02280 Protein ID WP_006622772.1
Coordinates 455414..455737 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APLC1_RS02240 (APLC1_0471) 450819..451988 - 1170 WP_006622761.1 phosphotransferase -
APLC1_RS02245 (APLC1_0472) 452229..452468 - 240 WP_006668952.1 hypothetical protein -
APLC1_RS02250 (APLC1_0473) 452485..452709 - 225 WP_006622763.1 UPF0175 family protein -
APLC1_RS02255 (APLC1_0474) 453144..453533 + 390 WP_006622766.1 type II toxin-antitoxin system VapC family toxin -
APLC1_RS02260 (APLC1_0475) 453537..453752 + 216 WP_006622767.1 hypothetical protein -
APLC1_RS02265 (APLC1_0476) 453952..454221 + 270 WP_006622768.1 hypothetical protein -
APLC1_RS02270 (APLC1_0477) 454383..454673 - 291 WP_006622769.1 type II toxin-antitoxin system VapC family toxin -
APLC1_RS02275 (APLC1_0478) 454676..454894 - 219 WP_006622770.1 DUF2281 domain-containing protein -
APLC1_RS02280 (APLC1_0479) 455414..455737 - 324 WP_006622772.1 helix-turn-helix transcriptional regulator Antitoxin
APLC1_RS02285 (APLC1_0480) 455742..456113 - 372 WP_006622773.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APLC1_RS02290 (APLC1_0481) 456198..456434 + 237 WP_006622774.1 type II toxin-antitoxin system HicB family antitoxin -
APLC1_RS02295 456471..456557 + 87 WP_230428128.1 type II toxin-antitoxin system HicA family toxin -
APLC1_RS02300 (APLC1_0482) 456688..457875 + 1188 WP_187758232.1 ATP-binding protein -
APLC1_RS02305 (APLC1_0483) 457868..458575 + 708 WP_006668943.1 hypothetical protein -
APLC1_RS02310 (APLC1_0484) 458674..458925 - 252 WP_006622777.1 hypothetical protein -
APLC1_RS02315 459169..459297 + 129 WP_008056050.1 hypothetical protein -
APLC1_RS02320 (APLC1_0485) 459340..459495 + 156 WP_006622779.1 hypothetical protein -
APLC1_RS02325 (APLC1_0486) 459492..459650 + 159 WP_006622780.1 hypothetical protein -
APLC1_RS02330 (APLC1_0487) 459699..459854 + 156 WP_006622781.1 hypothetical protein -
APLC1_RS02335 (APLC1_0488) 460107..460328 - 222 WP_006622783.1 hypothetical protein -
APLC1_RS02340 460331..460531 - 201 WP_231296472.1 type II toxin-antitoxin system HigB family toxin -
APLC1_RS02345 460787..461023 - 237 WP_192808262.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13866.90 Da        Isoelectric Point: 7.3535

>T73673 WP_006622773.1 NZ_CP019998:c456113-455742 [Arthrospira platensis C1]
MSELLKPVEWVGSSLEDLKEFPEEVRQGVGYALYLAQCGEKHPSAKPLKGFKGAGVLEVVEDFDGDTYRAVYTLKLAGVV
YVLHAFQKKSKKGIATPKQDIELIEGRLKRAKEHYSEHYINQQ

Download         Length: 372 bp

>T73673 NZ_CP019998:c456113-455742 [Arthrospira platensis C1]
ATGAGTGAATTACTAAAACCAGTTGAGTGGGTTGGCAGTTCTCTTGAGGATTTAAAGGAGTTCCCCGAGGAGGTTCGGCA
AGGTGTTGGTTATGCGCTATATCTGGCTCAATGTGGTGAAAAGCACCCGTCTGCGAAACCACTCAAAGGCTTTAAGGGGG
CTGGGGTGCTTGAAGTTGTCGAAGATTTTGACGGAGACACTTATCGAGCCGTTTACACTTTAAAGTTAGCTGGGGTGGTC
TATGTCCTCCACGCTTTTCAGAAGAAGTCAAAAAAAGGGATTGCCACGCCTAAGCAGGATATTGAGCTAATCGAGGGAAG
GCTTAAACGTGCCAAAGAACATTACTCCGAACATTACATCAATCAGCAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11622.43 Da        Isoelectric Point: 8.7690

>AT73673 WP_006622772.1 NZ_CP019998:c455737-455414 [Arthrospira platensis C1]
MNHPIKVQAGSGNVFADLELENSDELLVKAELARRISGIIAAQNMTQTEAAEMLGIDQPKVAALVNGKLSGFSTTRLFRF
LNALGRDVEIVVKPKSFRQAETRVVGL

Download         Length: 324 bp

>AT73673 NZ_CP019998:c455737-455414 [Arthrospira platensis C1]
ATGAATCACCCGATTAAAGTACAAGCAGGAAGTGGCAATGTATTCGCCGATTTAGAGTTAGAAAATTCTGATGAATTACT
GGTCAAGGCAGAACTTGCCCGGAGAATTAGTGGTATTATCGCCGCCCAAAATATGACTCAAACTGAGGCGGCAGAAATGT
TGGGAATTGACCAGCCTAAAGTGGCGGCATTAGTGAATGGCAAGCTATCGGGTTTTTCCACGACTCGGTTGTTTCGTTTT
TTAAATGCGTTGGGTCGGGATGTAGAAATCGTAGTAAAACCCAAGTCTTTCAGACAAGCTGAAACACGAGTGGTGGGGTT
GTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References