Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4246269..4246903 Replicon chromosome
Accession NZ_CP019967
Organism Rhodopseudomonas palustris strain YSC3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPYSC3_RS19650 Protein ID WP_107356566.1
Coordinates 4246269..4246670 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPYSC3_RS19655 Protein ID WP_107356567.1
Coordinates 4246667..4246903 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPYSC3_RS19615 4241385..4241708 + 324 WP_107345553.1 DUF1476 domain-containing protein -
RPYSC3_RS19620 4242381..4243199 - 819 WP_107356562.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
RPYSC3_RS19625 4243654..4243893 + 240 WP_107356563.1 hypothetical protein -
RPYSC3_RS19630 4243890..4244615 + 726 WP_107356564.1 Fic family protein -
RPYSC3_RS19635 4244669..4245154 - 486 WP_107357586.1 transcription elongation factor GreA -
RPYSC3_RS19640 4245215..4245718 - 504 WP_107357587.1 mismatch-specific DNA-glycosylase -
RPYSC3_RS19645 4245752..4246153 - 402 WP_107356565.1 DUF2147 domain-containing protein -
RPYSC3_RS19650 4246269..4246670 - 402 WP_107356566.1 type II toxin-antitoxin system VapC family toxin Toxin
RPYSC3_RS19655 4246667..4246903 - 237 WP_107356567.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RPYSC3_RS19660 4246966..4248162 - 1197 WP_107356568.1 TrmJ/YjtD family RNA methyltransferase -
RPYSC3_RS19665 4248553..4249776 + 1224 WP_107345565.1 NADP-dependent isocitrate dehydrogenase -
RPYSC3_RS19670 4249857..4251770 - 1914 WP_107356569.1 caspase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4236030..4258657 22627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(10-57)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 13920.83 Da        Isoelectric Point: 4.5201

>T73633 WP_107356566.1 NZ_CP019967:c4246670-4246269 [Rhodopseudomonas palustris]
VTRYMLDTSILSDLIRNPHGAAVRRIAEVGEGNVCTSIIVAAELRYGCATSGSVKLTKAAADLLEEIDVLPFEPPADEVY
GAIRSSLEAAGTPIGSNDLLIAAHAKSLGATIVTANTQEFGRVQGLAVENWLA

Download         Length: 402 bp

>T73633 NZ_CP019967:c4246670-4246269 [Rhodopseudomonas palustris]
GTGACGCGCTATATGCTCGATACCAGCATTCTCTCCGATCTGATCCGCAATCCGCACGGCGCTGCCGTTCGCCGCATCGC
TGAGGTCGGGGAGGGCAACGTCTGCACGAGTATCATCGTCGCCGCCGAACTCCGCTACGGCTGTGCCACGAGCGGGTCGG
TCAAATTGACCAAGGCCGCCGCCGATCTGCTCGAGGAAATCGACGTCCTGCCGTTCGAGCCGCCCGCCGACGAAGTCTAT
GGGGCGATCCGCTCATCGCTTGAAGCAGCAGGCACGCCGATCGGCAGCAACGACCTCCTGATCGCAGCTCACGCCAAGTC
GCTCGGTGCGACCATCGTCACCGCGAACACGCAGGAGTTTGGTCGCGTGCAGGGTTTGGCTGTCGAGAACTGGCTGGCGT
GA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8953.43 Da        Isoelectric Point: 7.2055

>AT73633 WP_107356567.1 NZ_CP019967:c4246903-4246667 [Rhodopseudomonas palustris]
MTDRRHVRLFRNGRNQAVRIPVEFEMPGNEAIMHREGDRLVIEPVRKRGLIALLQSMTPLDEPFPVIDDPAPAPEKVL

Download         Length: 237 bp

>AT73633 NZ_CP019967:c4246903-4246667 [Rhodopseudomonas palustris]
ATGACCGATCGGCGCCATGTCCGTCTGTTCCGTAACGGCCGCAATCAGGCCGTTCGCATTCCGGTGGAATTCGAGATGCC
CGGCAACGAAGCGATCATGCACCGCGAGGGGGATCGGCTGGTGATCGAGCCGGTCCGCAAACGCGGACTGATCGCTTTGT
TGCAATCGATGACGCCGCTCGACGAGCCGTTCCCCGTCATCGACGATCCCGCGCCGGCGCCGGAGAAGGTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References