Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3863528..3864159 Replicon chromosome
Accession NZ_CP019967
Organism Rhodopseudomonas palustris strain YSC3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPYSC3_RS17870 Protein ID WP_107356304.1
Coordinates 3863528..3863932 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPYSC3_RS17875 Protein ID WP_107357567.1
Coordinates 3863929..3864159 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPYSC3_RS17855 3858543..3858785 - 243 WP_011159021.1 hypothetical protein -
RPYSC3_RS17860 3859122..3860345 + 1224 WP_107356302.1 efflux RND transporter periplasmic adaptor subunit -
RPYSC3_RS17865 3860348..3863485 + 3138 WP_107356303.1 multidrug efflux RND transporter permease subunit -
RPYSC3_RS17870 3863528..3863932 - 405 WP_107356304.1 PIN domain-containing protein Toxin
RPYSC3_RS17875 3863929..3864159 - 231 WP_107357567.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RPYSC3_RS17885 3864615..3865028 + 414 WP_107356305.1 nucleotidyltransferase substrate binding protein -
RPYSC3_RS17890 3865025..3865357 + 333 WP_107356306.1 nucleotidyltransferase domain-containing protein -
RPYSC3_RS17895 3865368..3866561 - 1194 WP_107356307.1 CoA transferase -
RPYSC3_RS17900 3866667..3867878 - 1212 WP_107356308.1 ABC transporter substrate-binding protein -
RPYSC3_RS17905 3868116..3868730 - 615 WP_107356309.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14555.52 Da        Isoelectric Point: 5.1798

>T73632 WP_107356304.1 NZ_CP019967:c3863932-3863528 [Rhodopseudomonas palustris]
VTAFFDTNILVYAQETGAKADRARAVLGGGGRLSVQVLNEFTVVVQRKFGRGWREIAEAIDDALAVSGPPLPLTHDLHVA
ARVLAETCKLSFYDALIVAAAQEAGCEVLYSEDLQHGRSFGTLRVENPFLENPR

Download         Length: 405 bp

>T73632 NZ_CP019967:c3863932-3863528 [Rhodopseudomonas palustris]
GTGACGGCTTTCTTCGATACTAACATTCTAGTCTATGCTCAGGAAACGGGCGCGAAAGCGGACCGTGCACGGGCCGTCTT
GGGCGGCGGTGGCAGGCTCAGCGTTCAAGTGTTGAACGAGTTCACCGTCGTGGTGCAGCGCAAGTTCGGCCGGGGGTGGA
GGGAGATCGCCGAGGCTATCGACGACGCTCTGGCTGTGTCCGGGCCGCCACTGCCTCTGACGCACGATCTGCACGTTGCC
GCTCGCGTGCTCGCTGAGACGTGCAAGCTGTCGTTCTACGACGCGCTGATCGTCGCTGCCGCGCAGGAGGCCGGCTGCGA
GGTGCTGTACAGCGAGGATTTACAGCACGGCCGCAGCTTCGGCACGTTGCGCGTCGAAAATCCGTTTCTGGAAAATCCGC
GATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8939.19 Da        Isoelectric Point: 6.3983

>AT73632 WP_107357567.1 NZ_CP019967:c3864159-3863929 [Rhodopseudomonas palustris]
MKVSRWGNSLAVRLPNALVDKLDLKEGDELNVVDVVERTVVVEKEDRRKAALERMAERKWKLPEGYRFDRDEANER

Download         Length: 231 bp

>AT73632 NZ_CP019967:c3864159-3863929 [Rhodopseudomonas palustris]
ATGAAGGTCTCCAGATGGGGTAATAGCCTTGCCGTCAGGCTGCCGAATGCGCTGGTGGACAAGCTCGATCTGAAAGAGGG
CGACGAGCTCAACGTGGTCGACGTCGTCGAGCGGACGGTGGTGGTCGAGAAGGAGGACAGAAGGAAAGCCGCGCTGGAGC
GCATGGCCGAGCGTAAGTGGAAGTTGCCTGAGGGCTATCGCTTCGATCGTGACGAGGCCAACGAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References