Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1729680..1730296 Replicon chromosome
Accession NZ_CP019967
Organism Rhodopseudomonas palustris strain YSC3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag RPYSC3_RS08065 Protein ID WP_107354812.1
Coordinates 1730000..1730296 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RPYSC3_RS08060 Protein ID WP_107354811.1
Coordinates 1729680..1729997 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPYSC3_RS08035 1725089..1725670 - 582 WP_107354806.1 L,D-transpeptidase -
RPYSC3_RS08040 1725851..1727395 + 1545 WP_107354807.1 acetolactate synthase large subunit -
RPYSC3_RS08045 1727509..1727940 + 432 WP_107354808.1 DUF5413 family protein -
RPYSC3_RS08050 1728109..1728429 - 321 WP_107354809.1 hypothetical protein -
RPYSC3_RS08055 1729000..1729236 + 237 WP_107354810.1 hypothetical protein -
RPYSC3_RS08060 1729680..1729997 - 318 WP_107354811.1 putative addiction module antidote protein Antitoxin
RPYSC3_RS08065 1730000..1730296 - 297 WP_107354812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPYSC3_RS08075 1730740..1732020 - 1281 WP_107354813.1 hypothetical protein -
RPYSC3_RS08080 1732261..1732854 - 594 WP_107343619.1 DUF1134 domain-containing protein -
RPYSC3_RS08085 1732962..1733468 + 507 WP_107354814.1 hypothetical protein -
RPYSC3_RS08090 1733478..1734413 - 936 WP_107354815.1 ketopantoate reductase family protein -
RPYSC3_RS08095 1734499..1735086 + 588 WP_107354816.1 TetR/AcrR family transcriptional regulator C-terminal ligand-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-94)

Antitoxin

Uncharacterized protein HI1420

(8-98)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10967.53 Da        Isoelectric Point: 8.9596

>T73630 WP_107354812.1 NZ_CP019967:c1730296-1730000 [Rhodopseudomonas palustris]
MIDVRETVDFTNWLAALSDLRARLQIVRRIERIAAGNFGDAKSVGGAVKELRIDYGPGYRVYDTRRGDTVVILLCGGDKR
TQSKDIRKAKEIAEALED

Download         Length: 297 bp

>T73630 NZ_CP019967:c1730296-1730000 [Rhodopseudomonas palustris]
ATGATTGACGTTCGCGAAACAGTGGATTTCACGAACTGGCTCGCCGCCTTGAGCGACCTGCGCGCCCGTCTGCAGATCGT
TCGCCGGATCGAGCGGATTGCCGCGGGAAACTTCGGTGATGCCAAATCGGTTGGTGGCGCGGTGAAGGAGCTTCGGATCG
ACTACGGACCGGGCTACCGAGTTTACGACACGCGGCGCGGCGACACCGTCGTCATCCTGCTCTGCGGCGGCGACAAGCGG
ACGCAAAGCAAGGACATCCGGAAGGCTAAGGAAATTGCAGAGGCGTTGGAGGACTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11410.24 Da        Isoelectric Point: 10.7447

>AT73630 WP_107354811.1 NZ_CP019967:c1729997-1729680 [Rhodopseudomonas palustris]
MKVSKLKKFNAAEHLRTPEARAEYLNIVLADGDPNEVRDALNLVARAQGMSAIAKAAGVTREGLYKTLGENGNPEFATIL
RVFGAMGFRLTAELAKNKPRRKAVA

Download         Length: 318 bp

>AT73630 NZ_CP019967:c1729997-1729680 [Rhodopseudomonas palustris]
ATGAAGGTCAGCAAACTGAAGAAGTTCAACGCGGCCGAACACCTTCGTACACCGGAAGCCCGCGCGGAGTATCTGAACAT
CGTTCTCGCCGACGGCGACCCCAACGAAGTGCGTGACGCACTCAATCTCGTCGCTCGCGCGCAGGGCATGAGCGCGATCG
CCAAGGCCGCTGGCGTCACCAGAGAGGGACTCTACAAGACGCTCGGTGAGAACGGTAACCCCGAGTTCGCAACCATCCTC
CGGGTGTTCGGCGCCATGGGATTCCGGTTGACGGCAGAACTGGCCAAAAACAAGCCGAGAAGGAAAGCAGTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References