Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 4709274..4709860 Replicon chromosome
Accession NZ_CP019966
Organism Rhodopseudomonas palustris strain PS3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag RPPS3_RS21830 Protein ID WP_107345920.1
Coordinates 4709274..4709570 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RPPS3_RS21835 Protein ID WP_107345921.1
Coordinates 4709573..4709860 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPPS3_RS21820 4705040..4706092 + 1053 WP_107345918.1 hypothetical protein -
RPPS3_RS21825 4706153..4709215 + 3063 WP_107345919.1 excinuclease ABC subunit UvrB -
RPPS3_RS21830 4709274..4709570 + 297 WP_107345920.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPPS3_RS21835 4709573..4709860 + 288 WP_107345921.1 putative addiction module antidote protein Antitoxin
RPPS3_RS21840 4709904..4710212 - 309 WP_199852165.1 (2Fe-2S) ferredoxin domain-containing protein -
RPPS3_RS21845 4710535..4711788 - 1254 WP_107345923.1 acetyl-CoA C-acetyltransferase -
RPPS3_RS21850 4712002..4712385 + 384 WP_107345924.1 hypothetical protein -
RPPS3_RS21855 4712870..4713301 + 432 WP_107345925.1 nuclear transport factor 2 family protein -
RPPS3_RS21860 4713509..4713949 + 441 WP_107345926.1 hypothetical protein -
RPPS3_RS24690 4714092..4714238 - 147 WP_199851768.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-88)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11068.68 Da        Isoelectric Point: 9.6850

>T73629 WP_107345920.1 NZ_CP019966:4709274-4709570 [Rhodopseudomonas palustris]
MSTIRKTQEFERWLRNLRDSRARVRILLRLDRLELGNPGDVAPIGEGVSELRVHYGPGYRVYFVERGATLVVLLCGGDKS
SQAADIATAKRLARELED

Download         Length: 297 bp

>T73629 NZ_CP019966:4709274-4709570 [Rhodopseudomonas palustris]
ATGTCGACGATCCGAAAGACGCAAGAGTTCGAGCGCTGGCTGCGAAATCTGAGAGACAGCCGGGCTCGCGTTCGAATCCT
TTTGAGGCTCGATCGGCTGGAGCTAGGGAATCCTGGCGATGTCGCTCCTATTGGCGAGGGTGTCAGCGAGCTCCGCGTCC
ACTACGGGCCAGGTTATCGGGTTTATTTCGTTGAGCGCGGCGCAACTCTGGTCGTACTGCTCTGCGGCGGCGACAAGAGC
TCTCAGGCGGCTGATATCGCCACCGCGAAGCGACTGGCAAGAGAGTTGGAGGATTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 9854.28 Da        Isoelectric Point: 4.5026

>AT73629 WP_107345921.1 NZ_CP019966:4709573-4709860 [Rhodopseudomonas palustris]
MVSTTPFDAADYLDSPEMIADYLTEAFASEDPALITKAIGAVARAKGMSGVAEDTGLSRENLYRALGGGAKPEFATVLKV
LHALGISLVAQPKVA

Download         Length: 288 bp

>AT73629 NZ_CP019966:4709573-4709860 [Rhodopseudomonas palustris]
ATGGTGAGCACGACGCCGTTCGACGCCGCTGACTATCTCGATAGTCCCGAAATGATCGCGGACTATTTGACCGAAGCCTT
CGCATCCGAGGATCCGGCACTCATCACCAAGGCGATTGGCGCTGTCGCGCGCGCCAAGGGTATGAGCGGCGTCGCGGAAG
ACACGGGCCTGTCCCGAGAGAATCTGTACCGCGCGCTCGGCGGCGGCGCGAAACCCGAATTTGCGACCGTGCTGAAGGTG
CTGCACGCACTCGGCATCAGCTTAGTGGCACAGCCGAAGGTCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References