Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4222970..4223604 Replicon chromosome
Accession NZ_CP019966
Organism Rhodopseudomonas palustris strain PS3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPPS3_RS19630 Protein ID WP_107345562.1
Coordinates 4222970..4223371 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPPS3_RS19635 Protein ID WP_107345563.1
Coordinates 4223368..4223604 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPPS3_RS19600 4219205..4220023 - 819 WP_107345558.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
RPPS3_RS19605 4220485..4220724 + 240 WP_107345559.1 hypothetical protein -
RPPS3_RS19610 4220851..4221312 - 462 WP_107345560.1 hypothetical protein -
RPPS3_RS19615 4221372..4221854 - 483 WP_107346689.1 transcription elongation factor GreA -
RPPS3_RS19620 4221915..4222418 - 504 WP_107346690.1 mismatch-specific DNA-glycosylase -
RPPS3_RS19625 4222452..4222853 - 402 WP_107345561.1 DUF2147 domain-containing protein -
RPPS3_RS19630 4222970..4223371 - 402 WP_107345562.1 type II toxin-antitoxin system VapC family toxin Toxin
RPPS3_RS19635 4223368..4223604 - 237 WP_107345563.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RPPS3_RS19640 4223668..4224864 - 1197 WP_107345564.1 TrmJ/YjtD family RNA methyltransferase -
RPPS3_RS19645 4225254..4226477 + 1224 WP_107345565.1 NADP-dependent isocitrate dehydrogenase -
RPPS3_RS19650 4226607..4226939 + 333 WP_107345566.1 YnfA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4214385..4223604 9219


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(10-57)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14002.94 Da        Isoelectric Point: 4.6768

>T73626 WP_107345562.1 NZ_CP019966:c4223371-4222970 [Rhodopseudomonas palustris]
VTRYMLDTNILSDLIRNPHGAAVRRIAEVGEGNVCTSIIVAAELRYGCAKSGSVRLTKAVADLLEEIDVLPFEPPADEAY
GAIRSSLEAAGTPIGSNDLLIAAHAKSLGATIVTANTQEFGRVQGLAVENWLA

Download         Length: 402 bp

>T73626 NZ_CP019966:c4223371-4222970 [Rhodopseudomonas palustris]
GTGACGCGCTATATGCTCGATACCAACATTCTCTCCGATCTGATCCGCAATCCGCACGGCGCTGCTGTTCGCCGCATCGC
CGAGGTCGGAGAGGGCAACGTCTGCACGAGTATCATCGTCGCCGCCGAACTCCGCTACGGCTGCGCCAAGAGCGGGTCGG
TCAGATTGACCAAGGCCGTGGCCGATCTGCTCGAGGAAATCGACGTGCTGCCGTTCGAGCCGCCCGCCGACGAAGCCTAT
GGGGCGATCCGCTCATCGCTTGAAGCAGCAGGCACGCCGATCGGCAGCAACGACCTCCTGATCGCAGCTCATGCCAAGTC
GCTCGGTGCGACCATCGTCACCGCGAACACGCAGGAGTTTGGTCGCGTGCAGGGTTTGGCAGTCGAGAACTGGCTGGCGT
GA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8953.47 Da        Isoelectric Point: 8.9339

>AT73626 WP_107345563.1 NZ_CP019966:c4223604-4223368 [Rhodopseudomonas palustris]
MTDRRHVRLFRNGRNQAVRIPVEFEMPGNEAIMHREGDRLVIEPVRKRGLIALLKSMTPLDEPFPVIDDPAPAPEKVL

Download         Length: 237 bp

>AT73626 NZ_CP019966:c4223604-4223368 [Rhodopseudomonas palustris]
ATGACCGATCGGCGCCATGTCCGCCTGTTCCGTAACGGCCGCAATCAGGCCGTTCGCATTCCGGTGGAATTCGAGATGCC
CGGCAACGAGGCGATCATGCACCGCGAGGGGGATCGGCTGGTGATCGAGCCCGTTCGCAAACGCGGACTGATCGCTTTGT
TGAAATCGATGACGCCGCTCGACGAGCCGTTCCCCGTCATCGACGATCCCGCGCCGGCGCCGGAGAAGGTGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References