Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3834331..3834974 Replicon chromosome
Accession NZ_CP019966
Organism Rhodopseudomonas palustris strain PS3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RPPS3_RS17870 Protein ID WP_107345263.1
Coordinates 3834331..3834723 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RPPS3_RS17875 Protein ID WP_107345264.1
Coordinates 3834720..3834974 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPPS3_RS17855 3829334..3829576 - 243 WP_011159021.1 hypothetical protein -
RPPS3_RS17860 3829913..3831136 + 1224 WP_107345261.1 efflux RND transporter periplasmic adaptor subunit -
RPPS3_RS17865 3831139..3834276 + 3138 WP_107345262.1 multidrug efflux RND transporter permease subunit -
RPPS3_RS17870 3834331..3834723 - 393 WP_107345263.1 PIN domain-containing protein Toxin
RPPS3_RS17875 3834720..3834974 - 255 WP_107345264.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RPPS3_RS17885 3835442..3835855 + 414 WP_107345265.1 nucleotidyltransferase substrate binding protein -
RPPS3_RS17890 3835852..3836184 + 333 WP_107345266.1 nucleotidyltransferase domain-containing protein -
RPPS3_RS17895 3836195..3837388 - 1194 WP_107345267.1 CoA transferase -
RPPS3_RS17900 3837494..3838705 - 1212 WP_107345268.1 ABC transporter substrate-binding protein -
RPPS3_RS17905 3838943..3839557 - 615 WP_107345269.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-115)

Antitoxin

Antitoxin PemI-like

(2-55)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14317.37 Da        Isoelectric Point: 6.6345

>T73625 WP_107345263.1 NZ_CP019966:c3834723-3834331 [Rhodopseudomonas palustris]
VKAFFDTNILVYITTSDPRQQTAATCLSSGGVASVQVLNEFVHVARRKLRQDWPQIEVALKQLRAALDDVLPITLNTHAA
AVVLARDHRLPFHDALIVAAAQEAGCDVLYSEDLQHGRTFGALRVENPFL

Download         Length: 393 bp

>T73625 NZ_CP019966:c3834723-3834331 [Rhodopseudomonas palustris]
GTGAAGGCGTTCTTCGATACGAATATCCTCGTCTACATCACCACTTCGGACCCGCGTCAGCAGACGGCCGCAACTTGCCT
GAGCAGTGGTGGTGTGGCCAGCGTTCAGGTGCTCAACGAATTCGTCCACGTAGCGCGCCGAAAGCTTCGGCAAGACTGGC
CACAGATCGAAGTCGCGCTCAAGCAGCTTCGCGCCGCGCTCGATGACGTACTTCCGATCACTCTAAATACCCACGCCGCG
GCCGTTGTCCTTGCACGCGATCACAGGCTGCCGTTCCACGACGCGCTGATCGTCGCGGCTGCTCAGGAGGCTGGGTGTGA
TGTGCTGTACAGCGAAGACCTGCAGCACGGCCGCACCTTCGGCGCGCTGCGCGTCGAGAATCCGTTTCTGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9870.18 Da        Isoelectric Point: 5.2587

>AT73625 WP_107345264.1 NZ_CP019966:c3834974-3834720 [Rhodopseudomonas palustris]
MQVSKWGNSLAVRLPKALVDKLELKEGDELNVVDIVERTLVVEKENRRKAAVERLSKLQWKLPADYKFDRDEANERYRDE
ANDQ

Download         Length: 255 bp

>AT73625 NZ_CP019966:c3834974-3834720 [Rhodopseudomonas palustris]
ATGCAGGTGTCGAAATGGGGCAATAGCCTCGCCGTTAGGCTGCCCAAAGCTCTGGTCGACAAGCTCGAACTGAAAGAGGG
CGATGAGCTGAACGTGGTCGACATTGTCGAACGAACGCTGGTGGTGGAGAAGGAAAACCGGCGCAAGGCGGCGGTGGAGC
GCCTTTCCAAGCTGCAATGGAAACTTCCTGCCGACTACAAGTTTGATCGCGACGAGGCAAACGAGCGGTATCGCGACGAG
GCGAATGATCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References