Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2171524..2171758 | Replicon | chromosome |
| Accession | NZ_CP019953 | ||
| Organism | Escherichia coli M8 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2171525..2171628 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2171524..2171758 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B2H83_RS10700 | 2167791..2168087 | + | 297 | WP_129542093.1 | host-nuclease inhibitor protein Gam | - |
| B2H83_RS10705 | 2168093..2168878 | + | 786 | WP_063119826.1 | phage recombination protein Bet | - |
| B2H83_RS10710 | 2168875..2169555 | + | 681 | WP_129541926.1 | YqaJ viral recombinase family protein | - |
| B2H83_RS10715 | 2169588..2169782 | + | 195 | WP_129542092.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| B2H83_RS10720 | 2169775..2169963 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2169781..2169959 | - | 179 | NuclAT_0 | - | - |
| - | 2169781..2169959 | - | 179 | NuclAT_0 | - | - |
| - | 2169781..2169959 | - | 179 | NuclAT_0 | - | - |
| - | 2169781..2169959 | - | 179 | NuclAT_0 | - | - |
| B2H83_RS10725 | 2170070..2170351 | + | 282 | WP_001311878.1 | excisionase | - |
| B2H83_RS10730 | 2170317..2171393 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2171524..2171758 | + | 235 | - | - | Antitoxin |
| - | 2171525..2171628 | - | 104 | - | - | Toxin |
| B2H83_RS10735 | 2171786..2172127 | - | 342 | WP_000976492.1 | YebY family protein | - |
| B2H83_RS10740 | 2172140..2173012 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| B2H83_RS10745 | 2173016..2173390 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| B2H83_RS10750 | 2173529..2173759 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| B2H83_RS10755 | 2173861..2174517 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein | - |
| B2H83_RS10760 | 2174541..2175203 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2105973..2177260 | 71287 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T73578 NZ_CP019953:c2171628-2171525 [Escherichia coli M8]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT73578 NZ_CP019953:2171524-2171758 [Escherichia coli M8]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
