Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2395952..2396480 Replicon chromosome
Accession NZ_CP019948
Organism Methylocystis bryophila strain S285

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag B1812_RS11175 Protein ID WP_085771662.1
Coordinates 2396190..2396480 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B1812_RS11170 Protein ID WP_085771661.1
Coordinates 2395952..2396200 (+) Length 83 a.a.

Genomic Context

B1812_RS11150B1812_RS11160B1812_RS11170B1812_RS11175B1812_RS11195B1812_RS11155B1812_RS11165B1812_RS11185B1812_RS11190
Location: 2391820..2392602 (783 bp)
Type: Others
Protein ID: WP_085771657.1
Location: 2393212..2393916 (705 bp)
Type: Others
Protein ID: WP_085771659.1
Location: 2395952..2396200 (249 bp)
Type: Antitoxin
Protein ID: WP_085771661.1
Location: 2396190..2396480 (291 bp)
Type: Toxin
Protein ID: WP_085771662.1
Location: 2398832..2400265 (1434 bp)
Type: Others
Protein ID: WP_102938196.1
Location: 2392623..2392901 (279 bp)
Type: Others
Protein ID: WP_085771658.1
Location: 2393946..2395688 (1743 bp)
Type: Others
Protein ID: WP_158658714.1
Location: 2396894..2398117 (1224 bp)
Type: Others
Protein ID: WP_085771663.1
Location: 2398240..2398569 (330 bp)
Type: Others
Protein ID: WP_085773664.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B1812_RS111502391820..2392602+783WP_085771657.1ethanolamine ammonia-lyase subunit EutC-
B1812_RS111552392623..2392901-279WP_085771658.1hypothetical protein-
B1812_RS111602393212..2393916+705WP_085771659.1type 1 glutamine amidotransferase domain-containing protein-
B1812_RS111652393946..2395688-1743WP_158658714.1DUF885 domain-containing protein-
B1812_RS111702395952..2396200+249WP_085771661.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
B1812_RS111752396190..2396480+291WP_085771662.1type II toxin-antitoxin system RelE/ParE family toxinToxin
B1812_RS111852396894..2398117-1224WP_085771663.1DNA modification methylase-
B1812_RS111902398240..2398569-330WP_085773664.1protease inhibitor I42 family protein-
B1812_RS111952398832..2400265+1434WP_102938196.1DUF1800 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11381.21 Da        Isoelectric Point: 10.5908

>T73560 WP_085771662.1 NZ_CP019948:2396190-2396480 [Methylocystis bryophila]
MTYELAFLDDALKEWRKLDSTTRDQFKIKLAERLENPKVISARLHGAKERYKIKLRSAGFRLVYEVRDQELIVLVVAVGK
RERNEVYKTAARRRTD

Download         Length: 291 bp

>T73560 NZ_CP019948:2396190-2396480 [Methylocystis bryophila]
ATGACCTATGAGCTCGCCTTTCTTGACGACGCGTTGAAGGAATGGCGCAAGCTGGATAGCACCACTCGAGACCAGTTCAA
GATCAAGCTCGCCGAGCGGCTGGAAAACCCGAAAGTTATCTCCGCTCGTTTGCATGGCGCGAAAGAGCGCTACAAGATCA
AGTTGCGTAGCGCTGGTTTCCGCCTAGTCTATGAAGTTCGCGATCAGGAGTTGATCGTTCTTGTCGTGGCGGTCGGCAAG
CGCGAGCGCAACGAAGTTTACAAGACCGCCGCACGGCGGCGGACGGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8874.12 Da        Isoelectric Point: 4.5494

>AT73560 WP_085771661.1 NZ_CP019948:2395952-2396200 [Methylocystis bryophila]
MAHIVHATTVASISDLKKNPMGTVAAGEGFPVAILNRNEPAFYCIPAKAYEDLLERLEDLELNAVADAREGQAIHKISLD
DL

Download         Length: 249 bp

>AT73560 NZ_CP019948:2395952-2396200 [Methylocystis bryophila]
ATGGCGCATATCGTTCACGCGACCACGGTCGCGAGCATTTCGGATTTGAAGAAGAACCCCATGGGCACCGTTGCCGCCGG
CGAAGGGTTCCCCGTTGCGATCCTCAACCGCAACGAGCCTGCGTTCTATTGCATCCCTGCCAAGGCTTATGAAGATTTGC
TGGAGCGTCTCGAAGACCTCGAGCTGAACGCCGTTGCGGACGCGCGCGAAGGGCAGGCGATCCACAAGATTTCGCTCGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References