Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 982778..983481 Replicon chromosome
Accession NZ_CP019948
Organism Methylocystis bryophila strain S285

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag B1812_RS04465 Protein ID WP_085770515.1
Coordinates 983074..983481 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag B1812_RS04460 Protein ID WP_085770514.1
Coordinates 982778..983065 (+) Length 96 a.a.

Genomic Context

B1812_RS04430B1812_RS04435B1812_RS04440B1812_RS04445B1812_RS04460B1812_RS04465B1812_RS04455B1812_RS04470B1812_RS04475
Location: 978094..978285 (192 bp)
Type: Others
Protein ID: WP_158658595.1
Location: 978371..979612 (1242 bp)
Type: Others
Protein ID: WP_085770510.1
Location: 979780..980427 (648 bp)
Type: Others
Protein ID: Protein_862
Location: 980721..981650 (930 bp)
Type: Others
Protein ID: WP_085770511.1
Location: 982778..983065 (288 bp)
Type: Antitoxin
Protein ID: WP_085770514.1
Location: 983074..983481 (408 bp)
Type: Toxin
Protein ID: WP_085770515.1
Location: 982145..982498 (354 bp)
Type: Others
Protein ID: WP_085770513.1
Location: 983591..985198 (1608 bp)
Type: Others
Protein ID: WP_085770516.1
Location: 985195..986394 (1200 bp)
Type: Others
Protein ID: WP_085770517.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
B1812_RS04430978094..978285+192WP_158658595.1LLM class flavin-dependent oxidoreductase-
B1812_RS04435978371..979612+1242WP_085770510.1SfnB family sulfur acquisition oxidoreductase-
B1812_RS04440979780..980427+648Protein_862LysR family transcriptional regulator-
B1812_RS04445980721..981650+930WP_085770511.1MBL fold metallo-hydrolase-
B1812_RS04455982145..982498-354WP_085770513.1DsrE family protein-
B1812_RS04460982778..983065+288WP_085770514.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
B1812_RS04465983074..983481+408WP_085770515.1PIN domain-containing proteinToxin
B1812_RS04470983591..985198-1608WP_085770516.1efflux transporter outer membrane subunit-
B1812_RS04475985195..986394-1200WP_085770517.1efflux RND transporter periplasmic adaptor subunit-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin

SpoVT-AbrB domain

(18-54)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14918.15 Da        Isoelectric Point: 6.3580

>T73559 WP_085770515.1 NZ_CP019948:983074-983481 [Methylocystis bryophila]
MFCLDTNIVIFALNKRRPWIATRLDNELRAGTALIVPAIVLFELNYGIAKSDRADQARALLDGFLSAGIGQPAFDAEDAR
EAADIRAFLERQGTPIGPFDYLVAAQARRRGAALVTLNRREFERVPGLMVTDWAA

Download         Length: 408 bp

>T73559 NZ_CP019948:983074-983481 [Methylocystis bryophila]
ATGTTTTGTCTCGACACGAACATCGTCATCTTCGCCTTGAACAAGCGGAGGCCCTGGATCGCCACGAGGCTCGATAATGA
GCTGAGGGCGGGAACGGCGCTCATCGTCCCCGCGATCGTGCTGTTCGAGCTCAACTACGGAATCGCCAAGAGCGACCGAG
CCGATCAAGCGCGCGCCCTGCTCGATGGCTTCTTGTCCGCCGGGATAGGCCAGCCGGCCTTCGACGCGGAGGATGCGCGC
GAGGCCGCGGACATAAGGGCGTTCCTCGAACGGCAAGGGACGCCGATCGGCCCCTTCGACTATCTCGTCGCGGCGCAGGC
GCGGCGGCGCGGCGCGGCGCTGGTGACGCTCAACCGCCGCGAGTTCGAGCGCGTGCCCGGCCTGATGGTGACGGATTGGG
CGGCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10494.93 Da        Isoelectric Point: 4.9057

>AT73559 WP_085770514.1 NZ_CP019948:982778-983065 [Methylocystis bryophila]
MTASAGKPAQEKATAKLFMHGRSQAVRLPKEFRFEGKEVRVSKVGDKVILEPLKKEPFDVEAWRGSLDALGARDFLPDGL
PDDPPLEPDDSISFD

Download         Length: 288 bp

>AT73559 NZ_CP019948:982778-983065 [Methylocystis bryophila]
ATGACCGCCAGCGCCGGCAAGCCCGCCCAAGAGAAAGCGACCGCCAAGCTGTTCATGCACGGCCGCAGCCAGGCTGTGCG
CCTGCCGAAGGAGTTCCGCTTCGAGGGGAAAGAGGTGCGCGTCAGCAAGGTAGGCGACAAGGTGATCTTGGAGCCTTTGA
AAAAGGAGCCGTTCGACGTGGAAGCCTGGCGCGGGAGTCTCGACGCCTTGGGCGCGCGGGATTTCTTGCCCGACGGTCTG
CCCGATGATCCGCCCCTCGAGCCCGACGATTCGATATCATTCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References