Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 2282674..2284086 Replicon chromosome
Accession NZ_CP019947
Organism Pseudomonas sp. CC6-YY-74

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag B2D37_RS10445 Protein ID WP_079202619.1
Coordinates 2283517..2284086 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag B2D37_RS10440 Protein ID WP_079202618.1
Coordinates 2282674..2283513 (-) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B2D37_RS10425 2279107..2280984 - 1878 WP_079202615.1 MFS transporter -
B2D37_RS10430 2281362..2281691 - 330 WP_079202616.1 AzlD domain-containing protein -
B2D37_RS10435 2281691..2282401 - 711 WP_079202617.1 AzlC family ABC transporter permease -
B2D37_RS10440 2282674..2283513 - 840 WP_079202618.1 AraC family transcriptional regulator Antitoxin
B2D37_RS10445 2283517..2284086 - 570 WP_079202619.1 GNAT family N-acetyltransferase Toxin
B2D37_RS10450 2284335..2287817 + 3483 WP_079202620.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(19-151)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21579.95 Da        Isoelectric Point: 10.4306

>T73557 WP_079202619.1 NZ_CP019947:c2284086-2283517 [Pseudomonas sp. CC6-YY-74]
MFKPQLITLQRGALRIEPMLDADIPALVALAEANRQELIHMSGAQRLDWYRQGLLDQREGKALPFVIRLGEQLVGTTRFG
DFMPALPAAEIGWTWLDHSQHGTGLNVMVKYLMLRHAFENWRMVRVQLKTAASNLRAQRAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDQQWPALKQQLEARFSG

Download         Length: 570 bp

>T73557 NZ_CP019947:c2284086-2283517 [Pseudomonas sp. CC6-YY-74]
ATGTTCAAGCCGCAATTGATTACCCTGCAGCGCGGCGCGCTGCGTATCGAACCGATGCTCGATGCCGATATTCCGGCGCT
GGTCGCCCTGGCCGAAGCCAATCGCCAGGAGCTGATCCATATGAGCGGCGCCCAGCGCCTGGATTGGTACCGCCAGGGCC
TGCTCGATCAGCGTGAAGGCAAGGCGCTGCCGTTTGTCATTCGCCTCGGCGAGCAACTGGTGGGCACGACCCGTTTCGGC
GACTTCATGCCGGCGCTGCCCGCCGCCGAGATCGGCTGGACCTGGCTCGATCACAGCCAGCACGGCACCGGCCTGAACGT
CATGGTCAAGTACCTGATGCTGCGCCACGCCTTCGAGAACTGGCGCATGGTGCGCGTGCAGTTGAAAACCGCCGCCAGCA
ACCTGCGTGCGCAGCGCGCGATCGAAAAGCTCGGCGCGCAGCGCGAGGGCGTGTTGCGCAATCATCGCCGGCTGGCCGAC
GGGCGGCTGGATGACAGCGTGCTGTACAGCATCACCGATCAGCAGTGGCCGGCGCTCAAGCAACAGCTGGAGGCGCGTTT
CAGCGGCTGA

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 31232.60 Da        Isoelectric Point: 10.0190

>AT73557 WP_079202618.1 NZ_CP019947:c2283513-2282674 [Pseudomonas sp. CC6-YY-74]
MPSTEVERTRFWTSPELHGVELLHAHYIEQRFTPHVHEGFVFTVIEHGAQSFRHRGGDHLAPVGSMVLINPDELHTGSKA
HEQGWRYRGFYPDNRQIVGVMAELELDAGGLPSFADSVLHDPQLHRMFAELHRLLDSPASALQQQTAWREAILALFQRHA
RIPAGRAPGQEPRAVARAKELLSSQLAEPPSLEALAQAVNLSPFHFARVFRRATGLPPHAWLMQRRLEQARALLKNGCAP
LRVAMQLGFADQSHLGRQFKQTYGVGPGAYRKACRGRPG

Download         Length: 840 bp

>AT73557 NZ_CP019947:c2283513-2282674 [Pseudomonas sp. CC6-YY-74]
ATGCCATCGACTGAGGTTGAGCGCACCCGTTTCTGGACGTCGCCCGAGCTGCACGGGGTCGAGCTGCTGCATGCCCACTA
CATCGAACAACGCTTTACCCCGCATGTGCATGAGGGTTTTGTGTTCACGGTGATCGAGCACGGCGCGCAATCTTTCCGGC
ATCGTGGCGGCGACCACCTGGCGCCGGTCGGCAGCATGGTGCTGATCAATCCGGATGAACTGCACACCGGCTCCAAGGCC
CATGAGCAGGGTTGGCGCTACCGCGGTTTCTACCCCGATAACCGCCAGATCGTCGGAGTGATGGCCGAGCTCGAACTGGA
TGCGGGCGGTCTGCCGTCGTTTGCCGACAGCGTATTGCATGACCCGCAGTTGCACCGCATGTTCGCTGAGTTGCATCGGT
TGCTGGACAGTCCAGCCAGTGCCTTGCAGCAGCAGACCGCCTGGCGCGAGGCGATCCTGGCGTTGTTTCAGCGCCATGCG
CGGATTCCAGCTGGCCGCGCGCCAGGGCAGGAGCCGCGGGCCGTGGCGCGGGCCAAGGAATTGCTGAGCAGCCAGCTCGC
CGAGCCGCCGTCGCTGGAAGCGCTGGCCCAGGCGGTCAACCTGTCACCCTTCCATTTCGCCCGGGTGTTCCGCCGCGCCA
CCGGCTTGCCGCCCCACGCCTGGTTGATGCAGCGCCGGCTGGAGCAGGCCCGCGCTTTGCTGAAAAACGGCTGTGCGCCG
CTGCGCGTGGCCATGCAACTGGGCTTCGCCGATCAAAGCCACCTGGGTCGGCAGTTCAAGCAGACCTATGGCGTCGGCCC
GGGCGCATACCGCAAGGCCTGCCGCGGCCGGCCTGGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References