Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2184609..2184880 Replicon chromosome
Accession NZ_CP019944
Organism Escherichia coli strain DSM 103246

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2184739..2184842 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2184609..2184880 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Eco28_RS11260 2181165..2181827 - 663 WP_000944256.1 exodeoxyribonuclease X -
Eco28_RS11265 2181850..2182506 - 657 WP_021577595.1 carbon-nitrogen hydrolase family protein -
Eco28_RS11270 2182608..2182838 - 231 WP_000916763.1 DNA polymerase III subunit theta -
Eco28_RS11275 2182977..2183351 + 375 WP_021577594.1 CopC domain-containing protein YobA -
Eco28_RS11280 2183355..2184227 + 873 WP_080030105.1 copper homeostasis membrane protein CopD -
Eco28_RS11285 2184240..2184581 + 342 WP_000976472.1 YebY family protein -
- 2184609..2184880 - 272 - - Antitoxin
- 2184739..2184842 + 104 - - Toxin
Eco28_RS11290 2184977..2185633 + 657 WP_000812738.1 protein-serine/threonine phosphatase -
Eco28_RS11295 2185634..2185825 - 192 WP_001296140.1 YebW family protein -
Eco28_RS11300 2185930..2186166 - 237 WP_001295499.1 DUF1480 family protein -
Eco28_RS11305 2186283..2187722 - 1440 WP_080030451.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T73520 NZ_CP019944:2184739-2184842 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT73520 NZ_CP019944:c2184880-2184609 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References