Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapB(antitoxin) |
Location | 76417..76991 | Replicon | plasmid pB13-200C |
Accession | NZ_CP019874 | ||
Organism | Pseudomonas syringae pv. tomato strain B13-200 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | Q48BC5 |
Locus tag | XJ28_RS31795 | Protein ID | WP_003344395.1 |
Coordinates | 76614..76991 (+) | Length | 126 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | Q48BC4 |
Locus tag | XJ28_RS31790 | Protein ID | WP_004644067.1 |
Coordinates | 76417..76617 (+) | Length | 67 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XJ28_RS31770 | 71930..72493 | - | 564 | WP_010214078.1 | hypothetical protein | - |
XJ28_RS31775 | 72514..72936 | - | 423 | WP_007247232.1 | hypothetical protein | - |
XJ28_RS31780 | 72964..75252 | - | 2289 | WP_105224219.1 | type IV secretory system conjugative DNA transfer family protein | - |
XJ28_RS31785 | 75239..76324 | - | 1086 | WP_060404100.1 | thioredoxin fold domain-containing protein | - |
XJ28_RS31790 | 76417..76617 | + | 201 | WP_004644067.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
XJ28_RS31795 | 76614..76991 | + | 378 | WP_003344395.1 | PIN domain-containing protein | Toxin |
XJ28_RS31800 | 76981..78183 | - | 1203 | WP_105224220.1 | conjugal transfer protein | - |
XJ28_RS31805 | 78276..78923 | - | 648 | WP_007247237.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
XJ28_RS31810 | 78972..81113 | - | 2142 | WP_007247238.1 | DotA/TraY family protein | - |
XJ28_RS31815 | 81142..81744 | - | 603 | WP_007247239.1 | conjugal transfer protein TraX | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..82965 | 82965 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 13633.73 Da Isoelectric Point: 6.4723
>T73409 WP_003344395.1 NZ_CP019874:76614-76991 [Pseudomonas syringae pv. tomato]
VKGVLVDTSVWVEHFRNNSPELVNLLSQDRVLIHPMVIGELACGTPPDRSNTLTDLGDLRGAQQPTVSEVIAFLNTHKLY
GLGCGLVDMTLLASALLSGTALWTLDKRLERLASRMAVSYQPPTH
VKGVLVDTSVWVEHFRNNSPELVNLLSQDRVLIHPMVIGELACGTPPDRSNTLTDLGDLRGAQQPTVSEVIAFLNTHKLY
GLGCGLVDMTLLASALLSGTALWTLDKRLERLASRMAVSYQPPTH
Download Length: 378 bp
>T73409 NZ_CP019874:76614-76991 [Pseudomonas syringae pv. tomato]
GTGAAAGGCGTCCTGGTAGACACCTCCGTTTGGGTTGAGCACTTTCGCAACAACAGTCCAGAACTGGTGAACTTGCTCAG
CCAGGACCGGGTACTCATACACCCCATGGTGATCGGAGAACTGGCGTGTGGTACGCCACCTGATCGTTCGAACACCTTGA
CCGACCTTGGCGACCTACGAGGTGCACAACAACCCACGGTGAGTGAAGTCATCGCCTTTCTGAACACCCACAAGCTCTAC
GGCCTGGGCTGTGGGCTGGTGGATATGACGCTCCTGGCCTCCGCGTTATTGAGCGGCACAGCGCTTTGGACGTTAGACAA
GCGCCTGGAGCGTTTGGCTAGTCGCATGGCCGTGTCTTACCAGCCTCCTACTCACTAG
GTGAAAGGCGTCCTGGTAGACACCTCCGTTTGGGTTGAGCACTTTCGCAACAACAGTCCAGAACTGGTGAACTTGCTCAG
CCAGGACCGGGTACTCATACACCCCATGGTGATCGGAGAACTGGCGTGTGGTACGCCACCTGATCGTTCGAACACCTTGA
CCGACCTTGGCGACCTACGAGGTGCACAACAACCCACGGTGAGTGAAGTCATCGCCTTTCTGAACACCCACAAGCTCTAC
GGCCTGGGCTGTGGGCTGGTGGATATGACGCTCCTGGCCTCCGCGTTATTGAGCGGCACAGCGCTTTGGACGTTAGACAA
GCGCCTGGAGCGTTTGGCTAGTCGCATGGCCGTGTCTTACCAGCCTCCTACTCACTAG
Antitoxin
Download Length: 67 a.a. Molecular weight: 7445.66 Da Isoelectric Point: 7.0102
>AT73409 WP_004644067.1 NZ_CP019874:76417-76617 [Pseudomonas syringae pv. tomato]
MRTTVTIDDALYQRALEVADPAMDKADLFREAVQTFVRIQAAKRLMALGATLPTMEDIARRHEKAL
MRTTVTIDDALYQRALEVADPAMDKADLFREAVQTFVRIQAAKRLMALGATLPTMEDIARRHEKAL
Download Length: 201 bp
>AT73409 NZ_CP019874:76417-76617 [Pseudomonas syringae pv. tomato]
ATGAGAACGACCGTCACCATCGACGATGCGTTGTACCAACGTGCTCTGGAAGTCGCCGATCCGGCGATGGATAAGGCCGA
CCTGTTCCGTGAAGCCGTTCAGACGTTTGTGCGCATTCAAGCAGCTAAACGATTGATGGCCTTAGGGGCCACACTGCCAA
CGATGGAAGACATCGCCCGCCGACACGAGAAGGCACTGTGA
ATGAGAACGACCGTCACCATCGACGATGCGTTGTACCAACGTGCTCTGGAAGTCGCCGATCCGGCGATGGATAAGGCCGA
CCTGTTCCGTGAAGCCGTTCAGACGTTTGTGCGCATTCAAGCAGCTAAACGATTGATGGCCTTAGGGGCCACACTGCCAA
CGATGGAAGACATCGCCCGCCGACACGAGAAGGCACTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8B3GPE2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2S4IKB9 |