Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-StbC |
Location | 30023..30690 | Replicon | plasmid pB13-200A |
Accession | NZ_CP019872 | ||
Organism | Pseudomonas syringae pv. tomato strain B13-200 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A0Q0GBP3 |
Locus tag | XJ28_RS30280 | Protein ID | WP_002556038.1 |
Coordinates | 30274..30690 (+) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | E7PUB4 |
Locus tag | XJ28_RS30275 | Protein ID | WP_002556039.1 |
Coordinates | 30023..30277 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XJ28_RS30255 | 25431..26447 | - | 1017 | WP_057425386.1 | ABC transporter permease | - |
XJ28_RS30260 | 26540..28120 | - | 1581 | WP_105224134.1 | ABC transporter substrate-binding protein | - |
XJ28_RS30265 | 28239..28778 | - | 540 | WP_004642348.1 | D-alanyl-D-alanine dipeptidase | - |
XJ28_RS30270 | 28816..29676 | - | 861 | WP_004668209.1 | MurR/RpiR family transcriptional regulator | - |
XJ28_RS30275 | 30023..30277 | + | 255 | WP_002556039.1 | plasmid stabilization protein | Antitoxin |
XJ28_RS30280 | 30274..30690 | + | 417 | WP_002556038.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
XJ28_RS30285 | 30952..32907 | - | 1956 | WP_105224135.1 | relaxase/mobilization nuclease domain-containing protein | - |
XJ28_RS30290 | 32918..33247 | - | 330 | WP_060403683.1 | ribbon-helix-helix protein, CopG family | - |
XJ28_RS30295 | 33682..33960 | + | 279 | WP_105224136.1 | mobilization protein | - |
XJ28_RS30300 | 34034..34234 | - | 201 | WP_105224137.1 | hypothetical protein | - |
XJ28_RS30305 | 34303..35139 | - | 837 | WP_105224138.1 | DUF945 domain-containing protein | - |
XJ28_RS30310 | 35185..35562 | - | 378 | WP_105224139.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..125801 | 125801 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 14865.14 Da Isoelectric Point: 4.6579
>T73406 WP_002556038.1 NZ_CP019872:30274-30690 [Pseudomonas syringae pv. tomato]
MIVLDTNVVSEAMKPESHLAVRAWLNDQAAETLYLSSVTLAELLFGIGALPAGKRKDMLAQALDGLMGLFRDRVLPFDID
AARRYADLAVTAKTCGRGFPTPDGYIAAIAASRDFIVASRDTAPYEAVGVPVINPWEV
MIVLDTNVVSEAMKPESHLAVRAWLNDQAAETLYLSSVTLAELLFGIGALPAGKRKDMLAQALDGLMGLFRDRVLPFDID
AARRYADLAVTAKTCGRGFPTPDGYIAAIAASRDFIVASRDTAPYEAVGVPVINPWEV
Download Length: 417 bp
>T73406 NZ_CP019872:30274-30690 [Pseudomonas syringae pv. tomato]
ATGATCGTCCTCGATACCAACGTCGTTTCCGAGGCGATGAAGCCCGAGTCCCACTTGGCCGTGCGGGCCTGGCTGAACGA
TCAAGCCGCCGAAACGCTATACCTGTCCAGCGTGACGCTGGCCGAGCTGCTGTTTGGCATCGGGGCGCTCCCGGCCGGCA
AGCGCAAGGATATGCTGGCGCAGGCCCTTGACGGTCTAATGGGGCTGTTCAGGGATCGGGTGCTGCCATTCGATATCGAT
GCAGCACGGCGCTATGCCGATCTGGCCGTGACGGCAAAAACCTGCGGGCGAGGATTCCCGACACCTGACGGCTACATCGC
AGCGATTGCGGCATCGCGAGATTTCATCGTGGCGTCACGCGACACTGCACCCTATGAGGCGGTCGGTGTACCCGTCATCA
ATCCGTGGGAAGTGTGA
ATGATCGTCCTCGATACCAACGTCGTTTCCGAGGCGATGAAGCCCGAGTCCCACTTGGCCGTGCGGGCCTGGCTGAACGA
TCAAGCCGCCGAAACGCTATACCTGTCCAGCGTGACGCTGGCCGAGCTGCTGTTTGGCATCGGGGCGCTCCCGGCCGGCA
AGCGCAAGGATATGCTGGCGCAGGCCCTTGACGGTCTAATGGGGCTGTTCAGGGATCGGGTGCTGCCATTCGATATCGAT
GCAGCACGGCGCTATGCCGATCTGGCCGTGACGGCAAAAACCTGCGGGCGAGGATTCCCGACACCTGACGGCTACATCGC
AGCGATTGCGGCATCGCGAGATTTCATCGTGGCGTCACGCGACACTGCACCCTATGAGGCGGTCGGTGTACCCGTCATCA
ATCCGTGGGAAGTGTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9442.84 Da Isoelectric Point: 7.3219
>AT73406 WP_002556039.1 NZ_CP019872:30023-30277 [Pseudomonas syringae pv. tomato]
MAMLTVRNLPDDVHRALRVRAAQHGHSTEAEVREILAIAVKPETRVRLGEALAALGRKIGLTNEDFEVFNQVRDKTPAEP
LRFE
MAMLTVRNLPDDVHRALRVRAAQHGHSTEAEVREILAIAVKPETRVRLGEALAALGRKIGLTNEDFEVFNQVRDKTPAEP
LRFE
Download Length: 255 bp
>AT73406 NZ_CP019872:30023-30277 [Pseudomonas syringae pv. tomato]
ATGGCAATGCTGACAGTACGGAACTTGCCCGACGATGTACACCGCGCGCTACGAGTGCGGGCCGCCCAACACGGGCACAG
CACCGAGGCCGAAGTCCGCGAGATTCTGGCGATCGCAGTCAAGCCGGAGACGCGCGTTCGCCTAGGTGAAGCCTTGGCGG
CATTGGGTCGCAAGATCGGCCTGACGAACGAAGATTTCGAGGTCTTCAACCAAGTGCGAGACAAGACGCCGGCCGAGCCG
CTGAGGTTTGAATGA
ATGGCAATGCTGACAGTACGGAACTTGCCCGACGATGTACACCGCGCGCTACGAGTGCGGGCCGCCCAACACGGGCACAG
CACCGAGGCCGAAGTCCGCGAGATTCTGGCGATCGCAGTCAAGCCGGAGACGCGCGTTCGCCTAGGTGAAGCCTTGGCGG
CATTGGGTCGCAAGATCGGCCTGACGAACGAAGATTTCGAGGTCTTCAACCAAGTGCGAGACAAGACGCCGGCCGAGCCG
CTGAGGTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0Q0GBP3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2G9L5L9 |