Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5994573..5995092 Replicon chromosome
Accession NZ_CP019871
Organism Pseudomonas syringae pv. tomato strain B13-200

Toxin (Protein)


Gene name relE Uniprot ID F3IS01
Locus tag XJ28_RS29030 Protein ID WP_005760789.1
Coordinates 5994573..5994863 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag XJ28_RS29035 Protein ID WP_002551444.1
Coordinates 5994853..5995092 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XJ28_RS29005 5991535..5992164 + 630 WP_105224095.1 NAD(P)H-dependent oxidoreductase -
XJ28_RS29010 5992221..5992835 - 615 WP_005769904.1 histidine phosphatase family protein -
XJ28_RS29015 5992913..5993254 - 342 WP_003380754.1 hypothetical protein -
XJ28_RS29020 5993609..5994346 + 738 WP_007246584.1 hypothetical protein -
XJ28_RS29030 5994573..5994863 - 291 WP_005760789.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XJ28_RS29035 5994853..5995092 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
XJ28_RS29045 5995268..5995729 - 462 WP_007246583.1 GNAT family N-acetyltransferase -
XJ28_RS29050 5996101..5996595 + 495 WP_010209025.1 hypothetical protein -
XJ28_RS29055 5996635..5997909 - 1275 WP_105224096.1 OprD family porin -
XJ28_RS29060 5998139..5998345 - 207 WP_044392902.1 hypothetical protein -
XJ28_RS29065 5998565..5999671 - 1107 WP_010209016.1 agmatine deiminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11095.92 Da        Isoelectric Point: 10.0984

>T73405 WP_005760789.1 NZ_CP019871:c5994863-5994573 [Pseudomonas syringae pv. tomato]
MTYSLEFDARALKEWGKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLSG

Download         Length: 291 bp

>T73405 NZ_CP019871:c5994863-5994573 [Pseudomonas syringae pv. tomato]
ATGACTTATAGCCTCGAGTTTGATGCGCGAGCTCTGAAGGAATGGGGCAAATTAGGGGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCACCGCGCGTTGAAGCAAATCGTCTGCATGCGTTGCCCGACTGCTACAAAATCA
AACTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGAGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT73405 WP_002551444.1 NZ_CP019871:c5995092-5994853 [Pseudomonas syringae pv. tomato]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT73405 NZ_CP019871:c5995092-5994853 [Pseudomonas syringae pv. tomato]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACTCC
TTCGGAATTGCTGCGTCAAACCCTGCAGTATGTGGCAGAGCGCGGCCAGCTACCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCGTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M3B8F2

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References