Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 565949..566988 | Replicon | chromosome |
| Accession | NZ_CP019871 | ||
| Organism | Pseudomonas syringae pv. tomato strain B13-200 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | XJ28_RS02895 | Protein ID | WP_007244471.1 |
| Coordinates | 566413..566988 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | A0A2G9KX16 |
| Locus tag | XJ28_RS02890 | Protein ID | WP_005737550.1 |
| Coordinates | 565949..566416 (+) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XJ28_RS02865 | 561689..562819 | - | 1131 | WP_007244475.1 | Fic family protein | - |
| XJ28_RS02870 | 563066..564364 | + | 1299 | WP_007244474.1 | M20 family metallopeptidase | - |
| XJ28_RS02880 | 564535..565128 | - | 594 | WP_007244473.1 | hypothetical protein | - |
| XJ28_RS32395 | 565174..565674 | - | 501 | WP_010208159.1 | hypothetical protein | - |
| XJ28_RS02890 | 565949..566416 | + | 468 | WP_005737550.1 | helix-turn-helix domain-containing protein | Antitoxin |
| XJ28_RS02895 | 566413..566988 | + | 576 | WP_007244471.1 | PIN domain-containing protein | Toxin |
| XJ28_RS02900 | 567169..567420 | + | 252 | WP_005614049.1 | helix-turn-helix domain-containing protein | - |
| XJ28_RS02905 | 567420..568616 | + | 1197 | WP_007244470.1 | type II toxin-antitoxin system HipA family toxin | - |
| XJ28_RS02910 | 568738..569463 | + | 726 | WP_010208166.1 | N-acetylmuramoyl-L-alanine amidase | - |
| XJ28_RS02915 | 569521..569898 | + | 378 | WP_007244468.1 | DUF1311 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 565174..580599 | 15425 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21958.18 Da Isoelectric Point: 5.9343
>T73401 WP_007244471.1 NZ_CP019871:566413-566988 [Pseudomonas syringae pv. tomato]
MRHSPFTAFYDANVLYPAPLRDFLMHLALTGVYRARWSSQIHDEWKRNLLINRPELTREQLDRTSALMDKAVPDGLVSDY
QSLIEGLKLPDADDRHVLAAAIKCNASVIVTFKLKDFPKDVLDTFDMEPLHPDDFIADLWDLDKAAVLEAAQRQRASLRN
PAHSARQYLDKLLQQKLPETVKLLSDFEFLI
MRHSPFTAFYDANVLYPAPLRDFLMHLALTGVYRARWSSQIHDEWKRNLLINRPELTREQLDRTSALMDKAVPDGLVSDY
QSLIEGLKLPDADDRHVLAAAIKCNASVIVTFKLKDFPKDVLDTFDMEPLHPDDFIADLWDLDKAAVLEAAQRQRASLRN
PAHSARQYLDKLLQQKLPETVKLLSDFEFLI
Download Length: 576 bp
>T73401 NZ_CP019871:566413-566988 [Pseudomonas syringae pv. tomato]
ATGAGGCATTCGCCGTTTACAGCTTTCTATGACGCCAACGTCCTATACCCGGCACCGCTTCGTGACTTTCTGATGCACTT
GGCATTGACTGGCGTGTACCGCGCACGCTGGTCTTCTCAAATTCATGACGAGTGGAAGCGCAACCTTCTGATCAATCGTC
CAGAGCTTACCCGTGAGCAACTGGATCGCACGTCTGCGCTGATGGATAAGGCAGTGCCGGACGGTCTGGTATCTGATTAC
CAGTCGCTAATTGAAGGGCTTAAGCTGCCTGACGCCGATGATCGTCATGTGCTGGCGGCTGCAATCAAGTGCAATGCCTC
TGTCATCGTGACATTCAAACTCAAGGACTTTCCGAAAGACGTCCTCGATACGTTCGATATGGAGCCCTTGCACCCGGATG
ATTTCATTGCCGACCTTTGGGATCTCGACAAAGCCGCTGTTCTCGAAGCCGCACAACGGCAGCGAGCATCTTTGAGAAAC
CCGGCACACAGTGCAAGGCAATACCTCGATAAGCTGCTGCAGCAGAAGCTTCCCGAGACTGTAAAACTGCTTTCGGATTT
TGAGTTTCTGATCTGA
ATGAGGCATTCGCCGTTTACAGCTTTCTATGACGCCAACGTCCTATACCCGGCACCGCTTCGTGACTTTCTGATGCACTT
GGCATTGACTGGCGTGTACCGCGCACGCTGGTCTTCTCAAATTCATGACGAGTGGAAGCGCAACCTTCTGATCAATCGTC
CAGAGCTTACCCGTGAGCAACTGGATCGCACGTCTGCGCTGATGGATAAGGCAGTGCCGGACGGTCTGGTATCTGATTAC
CAGTCGCTAATTGAAGGGCTTAAGCTGCCTGACGCCGATGATCGTCATGTGCTGGCGGCTGCAATCAAGTGCAATGCCTC
TGTCATCGTGACATTCAAACTCAAGGACTTTCCGAAAGACGTCCTCGATACGTTCGATATGGAGCCCTTGCACCCGGATG
ATTTCATTGCCGACCTTTGGGATCTCGACAAAGCCGCTGTTCTCGAAGCCGCACAACGGCAGCGAGCATCTTTGAGAAAC
CCGGCACACAGTGCAAGGCAATACCTCGATAAGCTGCTGCAGCAGAAGCTTCCCGAGACTGTAAAACTGCTTTCGGATTT
TGAGTTTCTGATCTGA
Antitoxin
Download Length: 156 a.a. Molecular weight: 17233.75 Da Isoelectric Point: 5.2911
>AT73401 WP_005737550.1 NZ_CP019871:565949-566416 [Pseudomonas syringae pv. tomato]
MSSADATRTVLPGEKEIAAAVESSRQLAAFLTTKCDTQRIELVDETQQREVVELPMFALRLLGEILSELALGNAVKVVPI
HAELTTQEAADMLNVSRPHLVKMLDQGMLPHTKTGRHRRVKFADLMSYKQQRDQASREAMDELAAQAQELGMGYE
MSSADATRTVLPGEKEIAAAVESSRQLAAFLTTKCDTQRIELVDETQQREVVELPMFALRLLGEILSELALGNAVKVVPI
HAELTTQEAADMLNVSRPHLVKMLDQGMLPHTKTGRHRRVKFADLMSYKQQRDQASREAMDELAAQAQELGMGYE
Download Length: 468 bp
>AT73401 NZ_CP019871:565949-566416 [Pseudomonas syringae pv. tomato]
ATGAGCAGCGCAGACGCCACTCGCACCGTTCTTCCTGGGGAGAAAGAAATCGCTGCGGCGGTTGAATCAAGTCGGCAATT
AGCCGCGTTTCTTACAACGAAATGTGACACCCAGCGCATTGAGCTTGTGGACGAAACGCAACAGCGCGAAGTCGTCGAGC
TGCCTATGTTTGCGCTCCGTTTGCTCGGCGAAATTCTCAGTGAGCTTGCGCTGGGTAACGCCGTCAAGGTGGTCCCCATT
CATGCTGAACTCACTACTCAGGAAGCAGCAGACATGCTCAATGTGTCCCGGCCTCATCTGGTGAAGATGCTGGACCAAGG
CATGTTGCCGCACACTAAAACCGGCAGGCACCGCCGAGTCAAATTTGCTGATTTGATGAGCTACAAGCAGCAGCGCGACC
AGGCAAGTCGCGAAGCCATGGACGAGTTAGCCGCGCAAGCCCAAGAACTAGGGATGGGATATGAATGA
ATGAGCAGCGCAGACGCCACTCGCACCGTTCTTCCTGGGGAGAAAGAAATCGCTGCGGCGGTTGAATCAAGTCGGCAATT
AGCCGCGTTTCTTACAACGAAATGTGACACCCAGCGCATTGAGCTTGTGGACGAAACGCAACAGCGCGAAGTCGTCGAGC
TGCCTATGTTTGCGCTCCGTTTGCTCGGCGAAATTCTCAGTGAGCTTGCGCTGGGTAACGCCGTCAAGGTGGTCCCCATT
CATGCTGAACTCACTACTCAGGAAGCAGCAGACATGCTCAATGTGTCCCGGCCTCATCTGGTGAAGATGCTGGACCAAGG
CATGTTGCCGCACACTAAAACCGGCAGGCACCGCCGAGTCAAATTTGCTGATTTGATGAGCTACAAGCAGCAGCGCGACC
AGGCAAGTCGCGAAGCCATGGACGAGTTAGCCGCGCAAGCCCAAGAACTAGGGATGGGATATGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|