73314

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3242672..3243014 Replicon chromosome
Accession NZ_CP019797
Organism Stenotrophomonas acidaminiphila strain SUNEO

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0S1B3P0
Locus tag B1L07_RS14605 Protein ID WP_054667984.1
Coordinates 3242672..3242806 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0S1B3Z5
Locus tag B1L07_RS14610 Protein ID WP_054667986.1
Coordinates 3242862..3243014 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1L07_RS14580 3238547..3239479 - 933 WP_104939799.1 MBL fold metallo-hydrolase -
B1L07_RS14585 3239598..3239897 - 300 WP_104940291.1 hypothetical protein -
B1L07_RS14590 3239976..3241274 - 1299 WP_104939800.1 tryptophan--tRNA ligase -
B1L07_RS14595 3241384..3242181 + 798 WP_104939801.1 hypothetical protein -
B1L07_RS14600 3242251..3242472 - 222 WP_054667983.1 CsbD family protein -
B1L07_RS14605 3242672..3242806 - 135 WP_054667984.1 entericidin A/B family lipoprotein Toxin
B1L07_RS14610 3242862..3243014 - 153 WP_054667986.1 entericidin A/B family lipoprotein Antitoxin
B1L07_RS14615 3243142..3244062 - 921 WP_104939802.1 arginase -
B1L07_RS14620 3244272..3245669 + 1398 WP_104939803.1 oxygen-independent coproporphyrinogen III oxidase -
B1L07_RS14625 3245689..3246444 + 756 WP_104939804.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4626.55 Da        Isoelectric Point: 10.2040

>T73314 WP_054667984.1 NZ_CP019797:c3242806-3242672 [Stenotrophomonas acidaminiphila]
MKRMVALMMLSLFSIAVLSGCNTVAGAGKDVQKAGEKVEDAAKR

Download         Length: 135 bp

>T73314 NZ_CP019797:c3242806-3242672 [Stenotrophomonas acidaminiphila]
ATGAAGCGCATGGTTGCCCTGATGATGCTGTCGCTGTTCTCGATCGCGGTGCTGTCCGGCTGCAATACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCCGGCGAGAAGGTGGAGGACGCAGCCAAGCGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5203.10 Da        Isoelectric Point: 7.7213

>AT73314 WP_054667986.1 NZ_CP019797:c3243014-3242862 [Stenotrophomonas acidaminiphila]
MKRVLMLALLAMFSAGTLSACNTVAGAGKDMQKAGEKVEDKAHDCSDGKC

Download         Length: 153 bp

>AT73314 NZ_CP019797:c3243014-3242862 [Stenotrophomonas acidaminiphila]
ATGAAGCGAGTACTGATGCTGGCCCTGCTGGCCATGTTTTCGGCGGGAACGCTCAGCGCCTGCAACACCGTCGCCGGCGC
CGGCAAGGACATGCAGAAGGCCGGTGAGAAGGTCGAGGACAAGGCCCACGACTGCAGCGACGGCAAGTGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0S1B3P0

Antitoxin

Source ID Structure
AlphaFold DB A0A0S1B3Z5

References