Detailed information of TA system TA073313

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 3093028..3093707
• Replicon: chromosome
• Accession: NZ_CP019797
• Organism: Stenotrophomonas acidaminiphila strain SUNEO

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: B1L07_RS13845
• Protein ID: WP_104939686.1
• Coordinates: 3093279..3093707 (+)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A0S1B352
• Locus tag: B1L07_RS13840
• Protein ID: WP_054667729.1
• Coordinates: 3093028..3093279 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B1L07_RS13825	3088290..3088808	+	519	WP_054667724.1	hypothetical protein	-
B1L07_RS13830	3088970..3089524	+	555	WP_104939684.1	queuosine precursor transporter	-
B1L07_RS13835	3090124..3092928	-	2805	WP_104939685.1	bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase	-
B1L07_RS13840	3093028..3093279	+	252	WP_054667729.1	hypothetical protein	Antitoxin
B1L07_RS13845	3093279..3093707	+	429	WP_104939686.1	PIN domain-containing protein	Toxin
B1L07_RS13850	3094011..3095525	+	1515	WP_104939687.1	acetyl-CoA hydrolase/transferase family protein	-
B1L07_RS13855	3095595..3095933	-	339	WP_104939688.1	YegP family protein	-
B1L07_RS13860	3096066..3096326	-	261	WP_104939689.1	GIY-YIG nuclease family protein	-
B1L07_RS13865	3096344..3096787	-	444	WP_158681912.1	hypothetical protein	-
B1L07_RS13870	3096936..3097982	-	1047	WP_104939691.1	3-deoxy-7-phosphoheptulonate synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain toxin (1-141)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15758.15 Da
• Isoelectric Point: 9.2117

>T73313 WP_104939686.1 NZ_CP019797:3093279-3093707 [Stenotrophomonas acidaminiphila]
MRALLDVNVLIALHDSDHVHHHPASAWLRTHIAHGWASCPLTQNGCLRIMSQPGYAKPQPLGSLVSMLARSTSTPFHAFW
PDAISVLDRTHFQHAYIHSPRQLTDLYLLALAVHHGGRLVTFNRHIALSAVAGARPEHLVQL

Nucleotide

• Length: 429 bp

>T73313 NZ_CP019797:3093279-3093707 [Stenotrophomonas acidaminiphila]
ATGCGTGCGTTGCTCGACGTGAACGTGCTGATCGCACTGCACGACAGCGACCACGTCCACCATCACCCTGCCTCGGCCTG
GCTGCGCACGCATATCGCGCATGGCTGGGCCAGTTGTCCGCTTACCCAGAACGGTTGCCTGCGCATCATGTCCCAGCCCG
GATACGCCAAGCCGCAACCGCTGGGCAGCCTGGTGAGCATGCTGGCGCGTTCCACGTCCACGCCCTTCCATGCGTTCTGG
CCAGACGCCATCAGCGTGCTGGATCGCACGCATTTCCAGCACGCCTACATCCACAGTCCGCGACAGTTGACCGATCTGTA
CCTGCTGGCGCTCGCGGTGCACCACGGCGGGCGGCTGGTGACCTTCAACCGGCACATTGCGCTGAGTGCGGTAGCGGGCG
CGCGGCCCGAGCACCTGGTGCAGTTGTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9124.39 Da
• Isoelectric Point: 4.7962

>AT73313 WP_054667729.1 NZ_CP019797:3093028-3093279 [Stenotrophomonas acidaminiphila]
MRTTLDIADDVLFAAKELARREKKPLGQVISELARRAFAQSDAPWGTTGVAEPLADYGIHPLPPRGVVVSNELIDRLRDE
EGI

Nucleotide

• Length: 252 bp

>AT73313 NZ_CP019797:3093028-3093279 [Stenotrophomonas acidaminiphila]
ATGCGCACCACCCTCGACATCGCCGACGACGTGCTGTTTGCCGCCAAGGAGCTGGCACGCCGCGAGAAGAAGCCACTCGG
CCAGGTGATCAGCGAACTGGCGCGGCGGGCGTTCGCCCAGTCCGATGCCCCCTGGGGCACGACCGGCGTGGCCGAACCCC
TGGCCGATTACGGCATTCATCCGCTGCCGCCACGCGGCGTGGTGGTCAGCAATGAACTCATCGACCGCCTGCGCGACGAA
GAGGGCATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0S1B352