Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 29019..29608 Replicon plasmid pVbh_BscR1
Accession NZ_CP019790
Organism Bartonella schoenbuchensis R1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag BscR1v2_RS07770 Protein ID WP_078690368.1
Coordinates 29276..29608 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID N6UD03
Locus tag BscR1v2_RS07765 Protein ID WP_010703162.1
Coordinates 29019..29276 (+) Length 86 a.a.

Genomic Context

BscR1v2_RS08105BscR1v2_RS07755BscR1v2_RS07760BscR1v2_RS07765BscR1v2_RS07770BscR1v2_RS07780BscR1v2_RS07800BscR1v2_RS07805BscR1v2_RS07720BscR1v2_RS08150BscR1v2_RS08100BscR1v2_RS07725BscR1v2_RS07730BscR1v2_RS07735BscR1v2_RS07740BscR1v2_RS07745BscR1v2_RS07750BscR1v2_RS07775BscR1v2_RS07785BscR1v2_RS07790BscR1v2_RS07795BscR1v2_RS07810BscR1v2_RS07815
Location: 25053..25271 (219 bp)
Type: Others
Protein ID: WP_141638309.1
Location: 27960..28348 (389 bp)
Type: Others
Protein ID: Protein_48
Location: 28419..28946 (528 bp)
Type: Others
Protein ID: WP_078690367.1
Location: 29019..29276 (258 bp)
Type: Antitoxin
Protein ID: WP_010703162.1
Location: 29276..29608 (333 bp)
Type: Toxin
Protein ID: WP_078690368.1
Location: 29911..30156 (246 bp)
Type: Others
Protein ID: WP_078690369.1
Location: 32978..33259 (282 bp)
Type: Others
Protein ID: WP_078690372.1
Location: 33277..33576 (300 bp)
Type: Others
Protein ID: WP_078690373.1
Location: 24169..24441 (273 bp)
Type: Others
Protein ID: WP_078690365.1
Location: 24521..24691 (171 bp)
Type: Others
Protein ID: WP_194284961.1
Location: 24898..25053 (156 bp)
Type: Others
Protein ID: WP_010703154.1
Location: 25316..25744 (429 bp)
Type: Others
Protein ID: WP_010703155.1
Location: 25808..25999 (192 bp)
Type: Others
Protein ID: WP_010703156.1
Location: 26141..26434 (294 bp)
Type: Others
Protein ID: WP_010703157.1
Location: 26451..26732 (282 bp)
Type: Others
Protein ID: WP_078690366.1
Location: 27005..27316 (312 bp)
Type: Others
Protein ID: WP_010703159.1
Location: 27329..27652 (324 bp)
Type: Others
Protein ID: Protein_47
Location: 29669..29899 (231 bp)
Type: Others
Protein ID: WP_078690392.1
Location: 30267..30602 (336 bp)
Type: Others
Protein ID: WP_078690393.1
Location: 30817..31122 (306 bp)
Type: Others
Protein ID: WP_078690370.1
Location: 31251..32510 (1260 bp)
Type: Others
Protein ID: WP_078690371.1
Location: 33671..33873 (203 bp)
Type: Others
Protein ID: Protein_59
Location: 33921..34226 (306 bp)
Type: Others
Protein ID: WP_010703129.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BscR1v2_RS07720 (BscR1v2_016500)24169..24441-273WP_078690365.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
BscR1v2_RS08150 (BscR1v2_016510)24521..24691-171WP_194284961.1hypothetical protein-
BscR1v2_RS08100 (BscR1v2_016520)24898..25053-156WP_010703154.1hypothetical protein-
BscR1v2_RS08105 (BscR1v2_016530)25053..25271+219WP_141638309.1hypothetical protein-
BscR1v2_RS07725 (BscR1v2_016540)25316..25744-429WP_010703155.1type II toxin-antitoxin system HicB family antitoxin-
BscR1v2_RS07730 (BscR1v2_016550)25808..25999-192WP_010703156.1hypothetical protein-
BscR1v2_RS07735 (BscR1v2_016560)26141..26434-294WP_010703157.1HigA family addiction module antidote protein-
BscR1v2_RS07740 (BscR1v2_016570)26451..26732-282WP_078690366.1type II toxin-antitoxin system RelE/ParE family toxin-
BscR1v2_RS07745 (BscR1v2_016580)27005..27316-312WP_010703159.1transcriptional regulator-
BscR1v2_RS0775027329..27652-324Protein_47type II toxin-antitoxin system RelE/ParE family toxin-
BscR1v2_RS0775527960..28348+389Protein_48single-stranded DNA-binding protein-
BscR1v2_RS07760 (BscR1v2_016600)28419..28946+528WP_078690367.1hypothetical protein-
BscR1v2_RS07765 (BscR1v2_016610)29019..29276+258WP_010703162.1PemI proteinAntitoxin
BscR1v2_RS07770 (BscR1v2_016620)29276..29608+333WP_078690368.1type II toxin-antitoxin system PemK/MazF family toxinToxin
BscR1v2_RS07775 (BscR1v2_016630)29669..29899-231WP_078690392.1hypothetical protein-
BscR1v2_RS07780 (BscR1v2_016640)29911..30156+246WP_078690369.1type II toxin-antitoxin system HicB family antitoxin-
BscR1v2_RS0778530267..30602-336WP_078690393.1hypothetical protein-
BscR1v2_RS07790 (BscR1v2_016660)30817..31122-306WP_078690370.1hypothetical protein-
BscR1v2_RS07795 (BscR1v2_016670)31251..32510-1260WP_078690371.1hypothetical protein-
BscR1v2_RS07800 (BscR1v2_016680)32978..33259+282WP_078690372.1type II toxin-antitoxin system RelE/ParE family toxin-
BscR1v2_RS07805 (BscR1v2_016690)33277..33576+300WP_078690373.1HigA family addiction module antidote protein-
BscR1v2_RS0781033671..33873-203Protein_59tyrosine-type recombinase/integrase-
BscR1v2_RS07815 (BscR1v2_016700)33921..34226-306WP_010703129.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-virB4 / virB111..5576155761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11844.98 Da        Isoelectric Point: 10.6999

>T73310 WP_078690368.1 NZ_CP019790:29276-29608 [Bartonella schoenbuchensis R1]
MKRGEIWLVSLDPSSGYEQKGTRPVLIVSPEAFNRVTKTPVVLPITSGGSFARTAGFAVSLMGMGLHTTGVIRCDQPRAL
DIGARKGKKLETVPVMIMNEVLAKLSTFLT

Download         Length: 333 bp

>T73310 NZ_CP019790:29276-29608 [Bartonella schoenbuchensis R1]
ATGAAGCGGGGAGAAATTTGGTTAGTATCGCTTGATCCAAGTTCAGGATATGAGCAAAAAGGAACGCGTCCCGTGCTTAT
TGTATCACCAGAAGCATTTAATCGTGTGACTAAAACACCGGTTGTTTTACCCATTACAAGTGGGGGAAGTTTTGCAAGAA
CAGCGGGTTTTGCTGTTTCATTGATGGGAATGGGATTGCACACAACAGGTGTGATACGCTGTGATCAACCACGTGCTCTC
GATATAGGAGCGCGCAAAGGAAAAAAACTAGAAACGGTTCCTGTCATGATTATGAACGAAGTATTAGCTAAGTTGTCAAC
ATTCCTTACGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9370.81 Da        Isoelectric Point: 4.0330

>AT73310 WP_010703162.1 NZ_CP019790:29019-29276 [Bartonella schoenbuchensis R1]
MHTTKLRKVGGSVMLSIPPALLDVLHLVENTEVGLTIDNGCLIVQPQIFPSYTLDELLAQCDPLADLSDEETEWLDAKPV
SRELL

Download         Length: 258 bp

>AT73310 NZ_CP019790:29019-29276 [Bartonella schoenbuchensis R1]
ATGCACACAACGAAATTGCGTAAAGTTGGAGGGTCAGTTATGCTTTCTATACCACCTGCATTACTTGATGTTTTACACCT
CGTTGAAAATACTGAGGTTGGTTTGACTATTGATAATGGGTGTTTAATTGTACAACCTCAGATATTTCCTAGTTATACTC
TTGACGAATTGTTAGCTCAATGTGATCCTTTGGCTGATCTGAGTGATGAGGAAACAGAATGGCTTGATGCTAAACCTGTT
AGTAGAGAGCTCTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBN6UD03

References