Detailed information of TA system TA073302

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1273553..1274084
• Replicon: chromosome
• Accession: NZ_CP019781
• Organism: Bartonella sp. WD16.2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BWD162_RS05510
• Protein ID: WP_078705760.1
• Coordinates: 1273553..1273834 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: BWD162_RS05515
• Protein ID: WP_078705761.1
• Coordinates: 1273821..1274084 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BWD162_RS05470	1269070..1269930	+	861	WP_153300997.1	S49 family peptidase	-
BWD162_RS05475	1270131..1270397	+	267	WP_078706121.1	hypothetical protein	-
BWD162_RS05480	1270394..1270759	+	366	WP_078705754.1	head decoration protein	-
BWD162_RS05485	1270773..1271849	+	1077	WP_078705755.1	major capsid protein	-
BWD162_RS05490	1271851..1272195	+	345	WP_078705756.1	hypothetical protein	-
BWD162_RS05495	1272275..1272631	-	357	WP_194284875.1	BrnA antitoxin family protein	-
BWD162_RS05500	1272902..1273219	-	318	WP_078705758.1	type II toxin-antitoxin system HicB family antitoxin	-
BWD162_RS05505	1273209..1273463	-	255	WP_078705759.1	toxin HicA	-
BWD162_RS05510	1273553..1273834	-	282	WP_078705760.1	type II toxin-antitoxin system YafQ family toxin	Toxin
BWD162_RS05515	1273821..1274084	-	264	WP_078705761.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
BWD162_RS05520	1274220..1274741	+	522	WP_153300998.1	hypothetical protein	-
BWD162_RS05525	1274735..1275472	+	738	WP_078705762.1	phage baseplate assembly protein V	-
BWD162_RS05530	1275469..1275810	+	342	WP_078705763.1	GPW/gp25 family protein	-
BWD162_RS05535	1275807..1276631	+	825	WP_078705764.1	baseplate J/gp47 family protein	-
BWD162_RS05540	1276634..1277737	+	1104	WP_078705765.1	phage tail protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1242949..1293878	50929

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-82)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11179.86 Da
• Isoelectric Point: 9.7981

>T73302 WP_078705760.1 NZ_CP019781:c1273834-1273553 [Bartonella sp. WD16.2]
MRTIERTAVFKRDFKREMKGRHRHLLESDLRKIIEALANDQPLEPRHRDHALTGNWSDYRDCHIRPDLVLIYRLINQDRL
VLVRLGSHSELDL

Nucleotide

• Length: 282 bp

>T73302 NZ_CP019781:c1273834-1273553 [Bartonella sp. WD16.2]
ATGCGGACGATTGAGCGTACTGCTGTTTTTAAACGTGATTTCAAGCGTGAAATGAAAGGAAGGCATCGCCACCTTTTAGA
GAGTGATTTGCGCAAAATTATTGAAGCATTAGCCAATGACCAACCGTTAGAACCGCGGCATCGTGATCATGCATTAACCG
GAAATTGGAGTGATTACAGAGACTGCCATATTCGACCTGATTTGGTATTGATTTATCGTTTAATCAATCAGGATAGATTG
GTTTTGGTACGTCTTGGTTCTCATTCTGAACTTGATTTATGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9515.79 Da
• Isoelectric Point: 4.1271

>AT73302 WP_078705761.1 NZ_CP019781:c1274084-1273821 [Bartonella sp. WD16.2]
MVTSRMVQARVPEDIQNAASQVIQASGLSVSDVVRVLMTRIAQDKAIPSVLFQPNAKTLEAFAELETGGLKKFDSVDELF
DDLYADD

Nucleotide

• Length: 264 bp

>AT73302 NZ_CP019781:c1274084-1273821 [Bartonella sp. WD16.2]
ATGGTTACTAGTCGTATGGTTCAAGCACGTGTTCCAGAAGATATTCAGAATGCAGCTAGTCAGGTCATTCAAGCGTCGGG
TTTGTCAGTAAGTGATGTGGTTAGAGTATTGATGACCCGTATCGCGCAAGATAAAGCTATTCCATCAGTGTTGTTTCAAC
CTAATGCAAAAACATTAGAAGCTTTTGCTGAACTCGAAACAGGTGGTTTAAAAAAGTTTGATTCAGTAGACGAATTATTT
GATGATTTGTATGCGGACGATTGA