Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3287797..3288158 Replicon chromosome
Accession NZ_CP019725
Organism Xanthomonas perforans 91-118

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XPE_RS14715 Protein ID WP_005914328.1
Coordinates 3288024..3288158 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0G8WVL8
Locus tag XPE_RS14710 Protein ID WP_008576433.1
Coordinates 3287797..3287949 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XPE_RS14680 3282869..3283549 - 681 WP_008576441.1 dTMP kinase -
XPE_RS14685 3284018..3284560 - 543 WP_003486615.1 GTPase -
XPE_RS14690 3284557..3285474 - 918 WP_008576439.1 hypothetical protein -
XPE_RS14695 3285571..3285930 - 360 WP_003486613.1 hypothetical protein -
XPE_RS14700 3285994..3286446 - 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
XPE_RS14705 3286767..3287690 + 924 WP_008576436.1 arginase -
XPE_RS14710 3287797..3287949 + 153 WP_008576433.1 entericidin A/B family lipoprotein Antitoxin
XPE_RS14715 3288024..3288158 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XPE_RS14720 3288386..3288595 + 210 WP_003486601.1 CsbD family protein -
XPE_RS14725 3288762..3290051 + 1290 WP_008576429.1 tryptophan--tRNA ligase -
XPE_RS14730 3290102..3291124 + 1023 WP_046932138.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T73221 WP_005914328.1 NZ_CP019725:3288024-3288158 [Xanthomonas perforans 91-118]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T73221 NZ_CP019725:3288024-3288158 [Xanthomonas perforans 91-118]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5137.08 Da        Isoelectric Point: 8.2782

>AT73221 WP_008576433.1 NZ_CP019725:3287797-3287949 [Xanthomonas perforans 91-118]
MKRLLTLMVLALFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT73221 NZ_CP019725:3287797-3287949 [Xanthomonas perforans 91-118]
ATGAAGCGACTGCTGACACTGATGGTGCTGGCCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8WVL8

References