Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2735008..2735555 Replicon chromosome
Accession NZ_CP019725
Organism Xanthomonas perforans 91-118

Toxin (Protein)


Gene name relE Uniprot ID A0A0G9C4Q2
Locus tag XPE_RS12370 Protein ID WP_008574054.1
Coordinates 2735008..2735310 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag XPE_RS12375 Protein ID WP_008574056.1
Coordinates 2735298..2735555 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XPE_RS12340 2730337..2730945 + 609 WP_008574046.1 NAD(P)H-dependent oxidoreductase -
XPE_RS12345 2731183..2731893 - 711 WP_008574047.1 hypothetical protein -
XPE_RS12350 2732093..2733004 - 912 WP_033478804.1 LysR family transcriptional regulator -
XPE_RS12355 2733130..2733867 + 738 WP_008574050.1 SDR family oxidoreductase -
XPE_RS12360 2733927..2734826 + 900 WP_008574052.1 SDR family NAD(P)-dependent oxidoreductase -
XPE_RS12370 2735008..2735310 - 303 WP_008574054.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XPE_RS12375 2735298..2735555 - 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
XPE_RS12380 2735621..2736283 - 663 WP_008574057.1 hemolysin III family protein -
XPE_RS12385 2736461..2738956 + 2496 WP_008574058.1 DEAD/DEAH box helicase -
XPE_RS12390 2738953..2740410 + 1458 WP_008574059.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2724185..2735555 11370


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11522.33 Da        Isoelectric Point: 9.1267

>T73219 WP_008574054.1 NZ_CP019725:c2735310-2735008 [Xanthomonas perforans 91-118]
MAEIIWSVPALADLDAIADDIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQR
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T73219 NZ_CP019725:c2735310-2735008 [Xanthomonas perforans 91-118]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACGACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTCGAGCGATTGATTGAACACCCGGACAGCGGAAGCCGGC
CACAGGAACTCCAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGC
ATCGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT73219 WP_008574056.1 NZ_CP019725:c2735555-2735298 [Xanthomonas perforans 91-118]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp

>AT73219 NZ_CP019725:c2735555-2735298 [Xanthomonas perforans 91-118]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G9C4Q2

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References