Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
Location | 2735008..2735555 | Replicon | chromosome |
Accession | NZ_CP019725 | ||
Organism | Xanthomonas perforans 91-118 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0G9C4Q2 |
Locus tag | XPE_RS12370 | Protein ID | WP_008574054.1 |
Coordinates | 2735008..2735310 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q3BZM5 |
Locus tag | XPE_RS12375 | Protein ID | WP_008574056.1 |
Coordinates | 2735298..2735555 (-) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XPE_RS12340 | 2730337..2730945 | + | 609 | WP_008574046.1 | NAD(P)H-dependent oxidoreductase | - |
XPE_RS12345 | 2731183..2731893 | - | 711 | WP_008574047.1 | hypothetical protein | - |
XPE_RS12350 | 2732093..2733004 | - | 912 | WP_033478804.1 | LysR family transcriptional regulator | - |
XPE_RS12355 | 2733130..2733867 | + | 738 | WP_008574050.1 | SDR family oxidoreductase | - |
XPE_RS12360 | 2733927..2734826 | + | 900 | WP_008574052.1 | SDR family NAD(P)-dependent oxidoreductase | - |
XPE_RS12370 | 2735008..2735310 | - | 303 | WP_008574054.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
XPE_RS12375 | 2735298..2735555 | - | 258 | WP_008574056.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
XPE_RS12380 | 2735621..2736283 | - | 663 | WP_008574057.1 | hemolysin III family protein | - |
XPE_RS12385 | 2736461..2738956 | + | 2496 | WP_008574058.1 | DEAD/DEAH box helicase | - |
XPE_RS12390 | 2738953..2740410 | + | 1458 | WP_008574059.1 | ribonuclease H-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2724185..2735555 | 11370 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11522.33 Da Isoelectric Point: 9.1267
>T73219 WP_008574054.1 NZ_CP019725:c2735310-2735008 [Xanthomonas perforans 91-118]
MAEIIWSVPALADLDAIADDIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQR
IVLVHVMRWERALRRNRLSR
MAEIIWSVPALADLDAIADDIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQR
IVLVHVMRWERALRRNRLSR
Download Length: 303 bp
>T73219 NZ_CP019725:c2735310-2735008 [Xanthomonas perforans 91-118]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACGACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTCGAGCGATTGATTGAACACCCGGACAGCGGAAGCCGGC
CACAGGAACTCCAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGC
ATCGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACGACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTCGAGCGATTGATTGAACACCCGGACAGCGGAAGCCGGC
CACAGGAACTCCAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGC
ATCGTGCTGGTGCACGTCATGCGGTGGGAGCGCGCGCTTCGCAGGAACCGTCTTTCACGCTAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9686.18 Da Isoelectric Point: 10.0780
>AT73219 WP_008574056.1 NZ_CP019725:c2735555-2735298 [Xanthomonas perforans 91-118]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK
Download Length: 258 bp
>AT73219 NZ_CP019725:c2735555-2735298 [Xanthomonas perforans 91-118]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACCCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGAGCCTATGTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACACATG
GCGCGATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0G9C4Q2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2WGS6 |