73204

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 1012036..1013374 Replicon chromosome
Accession NZ_CP019706
Organism Pantoea alhagi strain LTYR-11Z

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag B1H58_RS04660 Protein ID WP_085068211.1
Coordinates 1012036..1012986 (-) Length 317 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A1W6B2R8
Locus tag B1H58_RS04665 Protein ID WP_004186793.1
Coordinates 1012979..1013374 (-) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1H58_RS04630 1007123..1008291 + 1169 WP_157130148.1 IS3 family transposase -
B1H58_RS04635 1008304..1008543 - 240 Protein_894 restriction endonuclease -
B1H58_RS04640 1008540..1009088 - 549 Protein_895 ATPase -
B1H58_RS04645 1009167..1010278 + 1112 WP_157130149.1 IS3 family transposase -
B1H58_RS04650 1010437..1010736 - 300 WP_085068209.1 hypothetical protein -
B1H58_RS04655 1010744..1011568 - 825 WP_085068210.1 hypothetical protein -
B1H58_RS04660 1012036..1012986 - 951 WP_085068211.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
B1H58_RS04665 1012979..1013374 - 396 WP_004186793.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
B1H58_RS04670 1013449..1014261 - 813 WP_085068212.1 DUF4942 domain-containing protein -
B1H58_RS04685 1015461..1015694 - 234 WP_085068215.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1005990..1028653 22663
- inside IScluster/Tn - - 1005990..1017613 11623


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-304)

Antitoxin

Protein of unknown function DUF6088

(7-114)


Sequences

Toxin        


Download         Length: 317 a.a.        Molecular weight: 36098.40 Da        Isoelectric Point: 4.5511

>T73204 WP_085068211.1 NZ_CP019706:c1012986-1012036 [Pantoea alhagi]
MDDLTKLFPDVADALGIESVAIVEKDYYIVELLRLLQPLAFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPVAGFSQ
QYSRGQRKSIRKDIIQTIIETITASDTFRMDEEYPKVTRDEYRYNEIPVRYPQEYAQIPCLRPFIKLELMETDLLEAAEN
RAISSLVMDLTKKGEVVRAFPCATIGSTQAEKLISMMRRTAASMRDVERAVDESLVRHIYDNFCIVREKGADVPVLKRFV
QECIEQDIQRYGAQYPEFCESPVEELKMGLEELASNPVYKERYLQFVTPMVFGESHVSWEEAYACFRITALDVIDA

Download         Length: 951 bp

>T73204 NZ_CP019706:c1012986-1012036 [Pantoea alhagi]
ATGGATGATTTAACAAAGCTATTCCCGGACGTTGCTGATGCTCTGGGCATTGAATCAGTTGCAATTGTAGAGAAAGATTA
TTACATCGTTGAGTTATTGCGATTGCTCCAGCCTCTGGCGTTTGACACACATCAACTGGTTTTTGCCGGTGGAACGGCAT
TGTCAAAAGCGGGGATATCTTTGAACAGGATGTCGGAGGACGTGGACATTAAGCTTGTTCCTGTCGCCGGTTTTTCCCAG
CAATATTCCAGAGGTCAGCGTAAAAGCATCCGTAAGGATATTATTCAGACCATTATCGAAACGATTACAGCCTCAGATAC
GTTTCGCATGGATGAAGAGTATCCAAAGGTTACTCGTGATGAATATCGCTATAATGAAATTCCGGTACGCTACCCGCAGG
AATATGCACAAATTCCCTGTTTAAGGCCATTTATCAAACTGGAACTGATGGAAACGGATTTGCTTGAGGCTGCGGAAAAT
CGTGCTATTAGCTCACTGGTAATGGATCTAACAAAGAAGGGCGAAGTAGTGAGGGCTTTTCCCTGCGCAACTATCGGTAG
CACGCAGGCTGAAAAACTGATCTCGATGATGCGCAGAACGGCTGCAAGTATGCGTGATGTGGAGCGTGCAGTGGATGAGT
CACTGGTGCGTCATATCTACGACAACTTTTGTATTGTTAGAGAAAAAGGTGCTGACGTTCCTGTTTTGAAGCGCTTTGTG
CAGGAATGTATTGAGCAGGATATCCAACGTTACGGTGCTCAGTATCCTGAATTCTGCGAGTCGCCTGTTGAAGAACTAAA
AATGGGGTTGGAAGAACTGGCGAGCAACCCTGTTTATAAGGAACGCTATCTGCAGTTTGTTACACCAATGGTGTTCGGTG
AAAGCCACGTTTCCTGGGAAGAGGCCTATGCCTGTTTTCGCATAACGGCATTGGATGTGATTGATGCATAG

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14400.75 Da        Isoelectric Point: 11.0360

>AT73204 WP_004186793.1 NZ_CP019706:c1013374-1012979 [Pantoea alhagi]
MTIKARIQSRLKRSKRYVFTRDDFKDLAGYDQIGRALRELMKEGQLLKVGYGVYTKARQNAITGKLMPAAPGGSAAVMIE
ALERLKVDYRLAGATSAYNSGKSTQIPASLEIKTSPRFKRTLSVGSSKLNG

Download         Length: 396 bp

>AT73204 NZ_CP019706:c1013374-1012979 [Pantoea alhagi]
ATGACCATAAAAGCTCGTATTCAGTCACGGCTGAAGCGCTCAAAGCGTTATGTTTTCACTCGTGACGATTTCAAAGATCT
TGCTGGCTACGATCAAATAGGCAGAGCACTGCGTGAGCTGATGAAGGAAGGGCAGCTACTGAAAGTAGGCTATGGCGTCT
ACACCAAAGCGCGGCAAAATGCGATTACCGGTAAGCTGATGCCTGCTGCTCCCGGAGGTTCTGCTGCGGTAATGATTGAG
GCGTTGGAACGTCTGAAAGTGGATTACCGTCTGGCAGGAGCAACAAGTGCCTACAACAGTGGTAAATCTACCCAGATCCC
CGCGTCACTTGAAATCAAAACCTCCCCCCGTTTCAAGAGAACATTGTCAGTAGGGAGCAGCAAACTAAATGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1W6B2R8

References